... competing inter-
ests.
Cumulative survival of patients with Alzheimer's disease with low (solid line) and high (dashed line) initial AOC levelsFigure 2
Cumulative survival of patients with ... also consistent with the finding of lower oxida-
tive resistance of plasma and CSF from AD patients com-
pared with controls [18]. These findings further indicate
that oxidative s...
... deposition of APP is widespread in the brain,
including the cortex and hippocampus. Phosphorylated
tau immunoreactivity is present in neurons and glia in the
cortex and hippocampus, and intracellular ... numerous regulatory proteins including CD59, clus-
terin, vitronectin, C1-inhibitor, C4-binding protein,
decay-activating factor, and Factor H, which inhibit differ-
ent s...
... these
findings. The relative risks for poor outcome of the two
polymorphisms and combination of both were 1.6, 1.84
and 1.80. This effect size was in line with the data pub-
lished by Baugh and ... allele with tuberculosis and (ii) of the -173 C allele
in combination with the -794 CATT
7
microsatellite with
severe malarial anemia, respectively [34,35]. These find-
ings se...
... details
1
Division of Infectious Diseases, Indiana University School of Medicine,
Indianapolis, IN, USA.
2
Moi University School of Medicine, Eldoret, Kenya.
3
Division of Biostatistics, Indiana University ... with the data
analysis, assisted in interpretation of the results and provided final approval
of the manuscript. MG assisted in interpretation of the results and provided
fin...
... left and right legs in the stride interval and its corre-
sponding CV.
Parkinson's disease group
Figure 2 shows an example of the stride intervals meas-
ured during walking with and without ... decreased in the
control group. Stride variability, which is an important
measure of motor performance and gait unsteadiness, is
increased in subjects with a history of fal...
... polymorphisms in the genes encoding IL-1α and IL-1β are also associated with
increased AD risk. Specifically, variations in the promoter region of IL1A and in the coding
region of IL1B influence ... Eldik LJ, Griffin WS:
In vivo and in vitro evidence supporting a role for the inflammatory
cytokine interleukin-1 as a driving force in Alzheimer pathogenesis.
Neurobiol...
... sta-
tistical analysis of Bcl-2 staining in normal, benign, and
cancerous tissue samples. Fisher's exact test was used to
test for associations in extent of epithelial and stromal
staining ... transformation and drug-resistant disease, resulting in poor
clinical outcome. Likewise, studies indicate improved clinical outcome with increased presence of
lymphocytes. Therefore,...
... con-
comitant or single DYS is associated with a considerable
risk for disease progression [20-22]. However, diagnosis
is very difficult because, in the early stages, both lesions
are indistinguisha ble ... Healthcare, Buckinghamshire, United Kingdom) dissolved in
50 ml of solvent to obtain an 8 mmol/L solution was instilled intravesically with a 12 Fr catheter into an empty
bla...
... population in
England. In so doing, we aim to provide evidence on the
relative merits of two prominent multi-attribute utility
measures for those involved in analysing and interpreting
economic ... investigation and took the pri-
mary role in analysing the data and drafting the paper. JM
and HS were the principal clinical investigators for the
original postnatal support worker...
... analysis, and statistical
analysis. TYW participated in the field work and coordination of the field
study and assisted with drafting the manuscript. SFC assisted with recruiting
participants with cognitive ... challenge to individuals with cognitive impairments in wayfinding is how to remain oriented, recall
routines, and trave l in unfamiliar areas in a way rel...