... for Parkinson's Research, and by a donation from Marcia and Howard Parven.References1. Beal MF: Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann NY Acad ... theother major C3 cleavage protein, is an anaphylatoxin,increasing vascular permeability. Though C 3a is generallyconsidered to be pro-inflammatory [27-29] because itattracts and activates eosinophils, ... eosinophils, basophils, and mastcells, few of these cells are present in the brain. C 3a may, in fact, limit brain inflammation, by decreasing the pro-duction of inflammatory cytokines and inducing the...