... correct folding of the recombinant pro-
teins, and the influence of N-glycosylation site occu-
pancy in the structure of the proteins. SPR and
PAGE studies confirm the ability of the nucleolin-
derived ... targeting of its
ligand [13]. Since N-glycosylation interferes with
the structure and the self-interaction properties of the
nucleolin-derived proteins,...
... iden-
tified as the major and the minor forms of the holo-
ACP structure, on the basis of their percentage contri-
butions (65% and 35%, respectively) to the overall
structure of the protein. The structures ... estimated on
the basis of the linear regression of the fraction number of the molecular mass markers cytochrome c (CyC), carbonic anhydrase (CA),...
... or
CtBP2 demonstrated the specificity and the reactivity
of these antibodies (Fig. 2C, top and middle panels;
compare lanes 3 and 4). Immunoprecipitation of total
cell extracts with the FLAG monoclonal ... transiently
transfected in triplicate with 100 ng of the indicated constructs,
350 ng of the pG5-Luc reporter and 50 ng of the pSG5-LacZ vector.
The cells...
... In
addition, they are not representative of all types of
ECs at various developmental stages and in vascular
beds [2]. On the other hand, the use of genetically
Keywords
Cre ⁄ loxP recombination; endothelial ... and
maintenance of murine endothelial cells from various
developmental stages and locations is important for
dissecting molecular and cellular mechanisms of endo...
... terms of the set
of mnemonics (that is, by the nodes in the mnemonic
tree), rather that in terms of the actual nonterminals of
the grammar. It is in this manner that we can obtain
efficient and ... that the geometric mean of the
number of parses per word, or equivalently the total num-
ber of parses for the entire test set, must be held con-
stant over...
...
the statistical tools used to analyze the data and
produce the bias-corrected tags (in section 3),
the case study of improving intercoder agree-
ment (in section 4), and the results of the ... Patterns of Disagreement
A probability model enforces constraints on the
counts in the data. The degree to which the
counts in the data conform to the constraints...
... of
before -and- after studies dealing with single-centre data
[52-56]. Inherent within this type of evidence is the lack of
rigour and generalisability. Furthermore, the magnitude of the
effect of the ... lack of statistical power due to the
large variance in outcome incidence and wide standard
deviation and the lower-than-expected incidence of the
outcome...
...
associated with these diseases
(1-6). Further, oxidative stress plays a major role in the
pathogenesis of both types of diabetes mellitus. High
levels of free radicals and the decline of antioxidant ... Popliteal and pedal
pulses were absent bilaterally with poor capillary re-
fill. The left foot was red and inflamed up to and in-
cluding the medial malleolu...
...
machines" can replace " ;the brain and hand, skill and
experience" of the specialist.
The aim of this study was to verify the reliability
and efficacy of one of these compact portable diode ... the suggestions of scientific literature
on the advantages of the compactness, reliability, ease
of use and affordability of the 980 nm Diode Las...
... of
CBMs.
Results and Discussion
Genetic engineering of the SBS
Residues of the SBS of both XBS and XAN involved
in substrate interaction were selected based on the
crystal structures of XBS and ... result suggests that the
function of the SBS is not merely to bring the enzyme
into contact with insoluble substrates, as is often pro-
posed as one of the funct...