Báo cáo hóa học: " The “Excellence in Translational Medicine” and “Bedside-to-Bench” Awards 2008-09" pptx

Tài liệu Báo cáo khoa học: The role in the substrate specificity and catalysis of residues forming the substrate aglycone-binding site of a b-glycosidase docx

Tài liệu Báo cáo khoa học: The role in the substrate specificity and catalysis of residues forming the substrate aglycone-binding site of a b-glycosidase docx

... site. This hypothesis was further investigated by deter- mining the in uence on the glycone binding of the Sfbgly interactions with the aglycone. Thus, the effect of the alteration of the glycone ... b-glycosidases and in designing inhibitors. In addition, another important issue in understand- ing the aglycone specificity is the contribution of the interactions wi...
Ngày tải lên : 18/02/2014, 17:20
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Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx

Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx

... corresponding reduction in protein stability [48,49]. However, in other studies, glycation of C-terminal lysines does not disrupt a-crystallin chaperoning [53] and activity increases when the pro- tein ... or unfavorable, depending on the disease. As a case in point, formation of huntingtin-containing inclusion bodies in Huntington’s disease encourages cell survival, whereas mon...
Ngày tải lên : 19/02/2014, 18:20
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Tài liệu Báo cáo khoa học: "The Thesaurus in Syntax and Semantics" docx

Tài liệu Báo cáo khoa học: "The Thesaurus in Syntax and Semantics" docx

... between the policy of interlingualizing the thesaurus, (that is, of assimilating semantics to syntax) and that of thesaurizing the syntax (that is, of in- cluding syntax within semantics) the linguists ... separation of the particular from the comparative universal range of validity (in MT terminology, of monolingual from interlingual features), and by their separate...
Ngày tải lên : 19/02/2014, 19:20
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Báo cáo khoa học:The principle of flux minimization and its application to estimate stationary fluxes in metabolic networks docx

Báo cáo khoa học:The principle of flux minimization and its application to estimate stationary fluxes in metabolic networks docx

... down-regulated in the anucleated erythrocyte) and the substrates fuelling the reaction are both p resent. On the other hand, despite some s ystematic differences to the r esults of kinetic modelling, the ... lactate. There is no thermodynamic or kinetic principle excluding the existence of such a h ypothetical g lucose-wasting and p yruvate- utilizing metabolic regime . Ho...
Ngày tải lên : 07/03/2014, 15:20
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Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx

Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx

... determined in the presence of 5 lm unlabeled agonist and subtracted from the total binding to calculate the spe- cific binding. Internalization of [ 3 H]BK and [ 3 H]DAK To determine the internalization ... 2004 FEBS The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B 1 and B 2 bradykinin receptors Alexander Faussne...
Ngày tải lên : 07/03/2014, 16:20
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Báo cáo khoa học: The propeptide in the precursor form of carboxypeptidase Y ensures cooperative unfolding and the carbohydrate moiety exerts a protective effect against heat and pressure pot

Báo cáo khoa học: The propeptide in the precursor form of carboxypeptidase Y ensures cooperative unfolding and the carbohydrate moiety exerts a protective effect against heat and pressure pot

... that the cleft of the active site will be located in the interface between the two structural domains of CPY and would be filled by the propeptide, thus uniting the two domains in a body, as if the ... perturbed by the carbohydrate moiety, thus increasing their fluorescence, since they are in close proximity to the carbohydrate-attachment sites, N13, 87, and 368. In...
Ngày tải lên : 07/03/2014, 21:20
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Báo cáo khoa học: The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5d differ in their ability to interact with the small GTPase Rab4 doc

Báo cáo khoa học: The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5d differ in their ability to interact with the small GTPase Rab4 doc

... Rabaptin-5 in the pPC86 vector and the Fig. 9. Mapping of the Rab4 binding site in Rabaptin-5 using the yeast two-hybrid protein–protein interaction assay. Indicated frag- ments of Rabaptin-5 ... chain and the Rab4 binding site of Rabaptin-5 are located in the N-terminal portion of protein. However, some discrepancy exists in the literature concerning the position...
Ngày tải lên : 16/03/2014, 18:20
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Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf

Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf

... [10,12]. Nevertheless, it is not possible to assume that the same is occurring in the mutant R97M, because there is no data on the interactions between the substrate and the arginine residue. Finally, another ... m M Bicine buffer 7.0–8.5). The pH stability of Sfbgly50 was checked by incubation in the same buffers for a time equal to the assay time and then determining...
Ngày tải lên : 23/03/2014, 15:21
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Báo cáo y học: " Regional coordination in medical emergencies and major incidents; plan, execute and teach"

Báo cáo y học: " Regional coordination in medical emergencies and major incidents; plan, execute and teach"

... [10]. The informa- Shows the gold command and control roomFigure 1 Shows the gold command and control room. Gold command and control centre in actionFigure 2 Gold command and control centre in action. BioMed ... anesthesiolo- gist with training in disaster medicine) was created. In this 24/7 system, the RTiB is the POC for the healthcare facili- ties within the r...
Ngày tải lên : 25/10/2012, 09:56
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 Báo cáo y học: "The association of meat intake and the risk of type 2 diabetes may be modified by body weight"

Báo cáo y học: "The association of meat intake and the risk of type 2 diabetes may be modified by body weight"

... anthropometrics and other lifestyle factors. Protocols for the SWHS were approved by the Institutional Review Boards of all institutes involved in the study. Dietary intake and other exposure information ... disease between the baseline and follow-up FFQs, only dietary data from the baseline FFQ were included in this analysis. For other participants the average of...
Ngày tải lên : 31/10/2012, 16:49
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