... site.
This hypothesis was further investigated by deter-
mining the in uence on the glycone binding of the
Sfbgly interactions with the aglycone. Thus, the effect
of the alteration of the glycone ... b-glycosidases and in designing
inhibitors.
In addition, another important issue in understand-
ing the aglycone specificity is the contribution of the
interactions wi...
... corresponding reduction in protein
stability [48,49]. However, in other studies, glycation
of C-terminal lysines does not disrupt a-crystallin
chaperoning [53] and activity increases when the pro-
tein ... or
unfavorable, depending on the disease. As a case in
point, formation of huntingtin-containing inclusion
bodies in Huntington’s disease encourages cell survival,
whereas mon...
... between the
policy of interlingualizing the thesaurus, (that
is, of assimilating semantics to syntax) and
that of thesaurizing the syntax (that is, of in-
cluding syntax within semantics) the linguists ... separation of the particular from the
comparative universal range of validity (in MT
terminology, of monolingual from interlingual
features), and by their separate...
... down-regulated in the anucleated erythrocyte) and the
substrates fuelling the reaction are both p resent. On the
other hand, despite some s ystematic differences to
the r esults of kinetic modelling, the ... lactate. There is no
thermodynamic or kinetic principle excluding the existence
of such a h ypothetical g lucose-wasting and p yruvate-
utilizing metabolic regime . Ho...
... determined in the presence of 5 lm unlabeled agonist
and subtracted from the total binding to calculate the spe-
cific binding.
Internalization of [
3
H]BK and [
3
H]DAK
To determine the internalization ... 2004 FEBS
The role of helix 8 and of the cytosolic C-termini in
the internalization and signal transduction of B
1
and B
2
bradykinin receptors
Alexander Faussne...
... that the cleft of
the active site will be located in the interface between the
two structural domains of CPY and would be filled by the
propeptide, thus uniting the two domains in a body, as if
the ... perturbed by the carbohydrate moiety, thus
increasing their fluorescence, since they are in close proximity
to the carbohydrate-attachment sites, N13, 87, and 368.
In...
... Rabaptin-5 in the pPC86 vector and the
Fig. 9. Mapping of the Rab4 binding site in Rabaptin-5 using the
yeast two-hybrid protein–protein interaction assay. Indicated frag-
ments of Rabaptin-5 ... chain and the Rab4 binding site of Rabaptin-5 are
located in the N-terminal portion of protein. However,
some discrepancy exists in the literature concerning the
position...
... [10,12].
Nevertheless, it is not possible to assume that the same is
occurring in the mutant R97M, because there is no data on
the interactions between the substrate and the arginine
residue.
Finally, another ... m
M
Bicine buffer 7.0–8.5). The
pH stability of Sfbgly50 was checked by incubation in the
same buffers for a time equal to the assay time and then
determining...
... [10]. The informa-
Shows the gold command and control roomFigure 1
Shows the gold command and control room.
Gold command and control centre in actionFigure 2
Gold command and control centre in action.
BioMed ... anesthesiolo-
gist with training in disaster medicine) was created. In this
24/7 system, the RTiB is the POC for the healthcare facili-
ties within the r...
... anthropometrics and
other lifestyle factors. Protocols for the SWHS were
approved by the Institutional Review Boards of all
institutes involved in the study.
Dietary intake and other exposure information ... disease between the baseline and
follow-up FFQs, only dietary data from the baseline
FFQ were included in this analysis. For other
participants the average of...