... al.: Multiplexed methylation profiles of
tumor suppressor genes and clinical outcome in lung cancer. Journal of
Translational Medicine 2010 8:86.
Submit your next manuscript to BioMed Central
and ... panel of candidate gen es selected could
be of clinical relevance for the clinicopathologic staging
of human lung tumors.
MS-MLPA profiles for clinical...
... KOOS
subscale Pain and the VAS-pain were between r = -0.28
and -0.79.
Floor and ceiling effects
Neither floor effects (indicating worst possible score) nor
ceiling effects (indicating best possible ... subscales Pain, Symptoms and ADL of the
KOOS questionnaire. It is plausible that these patients
have few complaints of their knee and have no or minor
clinical signs of OA, wh...
... shown that selected sigma-2
ligands are capable of inducing apoptosis in a multitude
of human and murine cancer cells lines and in animal
models of cancer including pancreas cancer [12,13,15].
The ... representing standard error of the mean.
The sigma-2 ligand, SV119, combined with gemcitabine sup-presses tumor growth and increases survival in model pan-creatic adenocarc...
... carried out and coordinated the study, immunohisto-
chemical examinations of tumor specimens and data
analysis, and drafted the manuscript. ZYZ and JF partici-
pated in the interpretation of data, ... Corresponding author
Abstract
Background: Tumor Protein p53 (p53), cyclin-dependent kinase inhibitor 1A (p21/WAF1), and
murine double minute 2 (MDM2) participate in the re...
... acquisition of
the data, was involved in drafting and revising the manuscript critically for
important intellectual content; NB contributed to the analysis and
interpretation of data, and was involved in ... statistical
analysis and interpretation of data, and drafted the manuscript; ML
participated in the design of the study and the statistical analysis and was
in...
... Counting backward (CB) is an attention-demanding task
frequently used in dual task paradigm involving gait [4].
Compared with other attention-demanding tasks used in
dual-task paradigms involving ... reliability of STV
under single and dual-task conditi ons. The objective of
this study was to examine immediate test-retest reliability
of STV while single and dual tasking in CHI...
... presence of a dominating five-coordinate
high-spin heme coexisting with some six-coordinate high-
spin heme. The A
406
/A
280
ratio (i.e. Reinheitszahl) of
Asn153fiAla varies between 0.46 and 0.48 ... the
cyanide complex and the ferric protein) and the corres-
ponding fit are shown in Fig. 4B. The observed rate of
cyanide binding to the ferric enzyme linearly increased with
the con...
... treatment for pancreatic cancer patients. The
preclinical finding of inhibition of CHK1 as a sensitizing
target for gemcitabine is currently being tested in clinical
trials. Collectively, the data presented ... targeting checkpoint kinase 1 (CHK1). Validation of the screening results was performed in MIA
PaCa-2 and BxPC3 pancreatic cancer cells by examining the dose response of...
... detection, cells were incubated in
PBS with 10 mM glucose containing 5 μM DAF-FM-DA for
30 min at 37°C. After the incubation, cells were washed
and incubated in the presence of either: inhibitors, stimu-
lators, ... (post intravenous
administration of 15 g, 30 g, and 60 g) and time of expo-
sure were established. The infusion of 15 g of ascorbic acid
in 45 min raised the...
... cytokines and chemokines and anti HBsAg serum titers in vaccinated healthy donorsFigure 3
Correlation between expression of genes encoding cytokines and chemokines and anti HBsAg serum titers in ... reverse
transcribed and amplified in the presence of primers and
probes specific for β-actin house keeping gene and genes
encoding different cytokines.
Expression of...