... cell
activity of several LOX inhibitors, including aesculetin (a
nonselective LOX inhibitor), MK886 (an inhibitor of the
5-LOX-activating protein), zileuton (a 5-LOX inhibitor),
baicalein (a 12/15-LOX inhibitor), ... pro-
mote apoptosis. In fact, ROS-induced oxidative stress
and cell death play important roles in the efficacy of many
antineoplastic agents [13,14].
To investigat...
... not die within 24 h of observation.
Determination of lipid peroxidation and nitrite
content
For all of the experimental procedures, 10% (w ⁄ v) homo-
genates of the area of the brain investigated ... (2002)
Attenuating effects of melatonin on pilocarpine-induced
seizures in rats. Comp Biochem Physiol C Pharmacol
Toxicol Endocrinol 131, 521–529.
20 Marinho MMF, Sousa FCF, Bruin V...
... of HCV infec-
tion in the etiopathogenesis of MC, showing the
presence of the viral RNA and/or anti-HCV antibodies
in a range of 70 to 100% of M C [6-8]. Furthermore, the
clinical evolution of ... VK3-20) of circulating APC populations.
Cytokine production in VK3-20-loaded PBMCs
In order to evaluate the impact of the VK3-20 protein
stimulation on the production of cy...
... sim-
ilarity of two arbitrary objects a and b is a function
of the information gained by giving a joint descrip-
tion of a and b in terms of what they have in com-
mon, compared to describing a and ... of the European Chapter of the Associa-
tion for Computational Linguistics.
D. Lin. 1998. An information-theoretic definition
of similarity. In Proc. International Conference...
... final manuscript.
Author Details
1
Institute of Reproductive and Stem Cell Engineering, Central South University,
Changsha 410008, China,
2
Institute of Spine Surgery, 2nd Xiangya Hospital of ... effect of Adel55 in nude mice tumor model by increasing Adel55 spreading and tu-
mor apoptosis. (A) Detection of HSF1 expression, Adel55 spreading or apoptotic rates in tumors. 30 da...
... long-
lasting effects of thiol-directed oxidative stress, and, in
particular, its in uence on the inter-organ exchange of
LMM-SH.
Results
In a first set of experiments, the kinetics of plasma
thiols ... The paucity of information in
this field is due, at least in part, to the intrinsic diffi-
culty in creating reliable animal models of oxidative
stress. Acute carbon...
... –Ca
2+
,
15 min in incubation medium; Ca
2+
, 15 min in incubation medium
plus 3.5 l
M Ca
2+
;H⁄ R, 10 min hypoxia followed by 5 min reoxy-
genation; CSA, 2 l
M cyclosporin A. A volume of 2 mL of the incu-
bation ... sug-
gests that the mitochondrial injury is caused by open-
ing of the mPTP. There is evidence that ADP inhibits
opening of the mPTP by occupying binding sites
locate...
... point to the involve-
ment of oxidative stress in the early stages of symbiosis
breakdown. In fact, several authors have suggested the
involvement of ROS production in the zooxanthella
photoinhibition ... bleaching of the experimental animals occurred
as the heat stress incubation progressed. This result
supports the induction of a bleaching event as a conse-
quence of...