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Results
BPA induces dose dependent apoptosis in acute myeloid
leukemia cells
To understand the potential role of BPA in biological sys-
tems of leukemias we tested the action of BPA in ... activity of these compounds
[17,18]. In the present manuscript, we decided to investi-
gate the effects of different doses of BPA on acute myeloid
l...
... observations
about the role of exosomes in antigen presentation, the
exacerbated production of these vesicles by tumor cells
was initially welcomed as a process potentially involved
in the induction and maintenance ... slow-down thanks to the recovery of specific
immunity and the interruption of paracrine/autocrine
loops in tumor microenvironment. Prior to any clinical...
... days, the the pancreas were isolated for hematoxylin and eosin staining or anti-insulin
immuohistaining. A, Representative morphology of pancreatic islets. a-f: hematoxylin and eosin staining. Arrow ... reduced insulin sensitiv-
ity, combined with reduced insulin secretion. Insulin
resistance forces pancreatic beta cells to produce more
insulin, which ultimately results in exhaustion...
... the sur-
face of cardosin A may be involved in the interaction
between these two proteins. To identify the cardo-
sin A-interacting protein from the pollen of Cynara
cardunculus L, the protein ... fur-
ther the specificity of the interaction, native cardosin B
was used in the binding assays. Despite the high simi-
larity between the two pistil aspartic proteinases...
... mutations in SLC26A4 result-
ing in hearing loss, enlargement of the vestibular aque-
duct (EVA) and iodine organification defect in the thyroid
gland[15]. EVA is always detected in the ears of patients
with ... alone
or in combination with an incomplete partition of the
apical turn of the cochlea as part of Mondini deformity. PS
is differentiated from nonsyndrom...
... and the writing of the
manuscript. FMM participated in designing the study and the writing of the
manuscript. DFS participated in designing the study, coordinating the study
and the writing of the ... thank the staff of the NIH, Clinical Center, Dowling Clinic, Department of
Transfusion Medicine, Clinical Center, NIH for collecting the cells and the Cel...
... according to a
number of parameters, including the degree of required
precision of the person and item estimates, and the target-
ing of the sample. A well targeted sample is one in which
the person ... provides further evidence for the
internal validity of the physical and psychological impact
scales of the MSIS-29, supporting their use in clinical and
researc...
... the line that joined both
epicondyles in the lateral direction. In the hand, the ori-
gin was at the midpoint between radial and ulnar styloid
ofthewrist,theY-axiswasthelinejoiningtheheadof
the ... rotations of the forearm.
In each recording, a complete cycle of the drinking
task was identified. The beginning of the cycle was the
onset o f displacement of...
... entrance of the protein TCP-1a into the
nucleus as well as translocation of nuclear annexin IV from
the nucleus to the cytosol, as deduced from the comparative
analysis of the protein pattern of the ... assessed in more detail,
Rout et al. interpreted the significance of the identification
of the other proteins in three ways: firstly, there are proteins
that...
... also present in the herbicide SSH lib-
raries (including glutamine synthetase and cathepsin).
In our experiments, we tested a cocktail of the three
more common herbicides detected in the French ... binding protein to form LGBP has been shown to
activate the prophenoloxidase cascade. The apolipo-
phorin precursor protein we identified is also involved
in the activation of...