... protein-protein
interactions. THD2 consists of one or more PEST signals
rich in proline, serine and threonine residues, while
THD3 harbors a novel PHD zinc finger- and/ or bromodo-
main-interacting ... purposes)
Journal of Translational Medicine
Open Access
Research
TRIP-Br2 promotes oncogenesis in nude mice and is frequently
overexpressed in multiple human tumo...
... the case of SUI an increase in
intraabdominal pressure (induced by activities such as
coughing, laughing, sneezing, lifting of heavy loads or
using stairs) causes involuntary urinary leakage without
contraction ... the domains of physical well-being,
social well-being, emotional well-being and functional
well-being.
Incontinence Quality of Life Instrument (I-QOL)
The Incontinence Quality...
... found integrin alpha 3, integrin beta 2 and
intercellular adhesion molecule 1 to be upregulated in
adenocarcinomas, while 6 genes, including the desmo-
somal cadherins desmoglein 3 and desmocollin ... 5/
6, and p63 immunostaining in classification of lung carcino-
mas. Appl Immunohistochem Mol Morphol 2007, 15:415-20.
29. Ordóñez NG: Value of cytokeratin 5/6 immunostaining in dis-...
... fail, in vitro and in vivo,toproduce
inflammatory cytokines in response to LPS and are pro-
tected against LPS-induced sepsis in vivo [1 9,22-24].
There is, however, a resounding lac k of experimental
evidence ... Similar to our findings in
human IRAK4-deficient monocytes, a number of che-
mokines were expressed a t similar levels in murine
BMDM from wildtype and IRAK4-ki...
... sequences, in the analysis
and interpretation of data, and helped to draft the manu-
script. LC, BP, PGN, and PN, have been involved in draft-
ing and critically revising the manuscript. LI conceived
and ... of certain TRBJ and TRBV
segments, indicates an important role of the TRB chain in
fine-tuning TR affinity of Melan-A-specific T cells of
melanoma patients and argues...
... immunofluorescence and immunohistochemistry
CAV1 and topoisomerase-alpha protein expression in tis-
sue and cells was studied by Immunofluorescence and
Immunohistochemistry. As shown in Figure 4B and Fig-
ure ... However, increased pro-
liferation was not accompanied by a reduction in cell
death in CAVM1 cells. An intriguing mechanism, in this
regard, is the presence of...
... that CHK1 is essential for maintaining
gemcitabine-induced S-phase arrest whereas CHK2 is not.
This is in accordance with previously published data
[39,40].
Loss-of-function screening using siRNA ... gemcitabine, the standard agent in pancre-
atic cancer chemotherapy. Literature review shows that
combination therapies involving gemcitabine and other
agents, such as axitinib, cispl...
... histo-
chemical staining was made for A, D, E, and F groups. As
a result of staining with antibody of other 3 angiogenesis
related protein, applied to this test, in each tissue, no his-
tochemical staining ... staining as shown in Figure 4A. We observed blue
staining of giant nuclei followed by cancer cell genesis,
and identified cancer genesis in tissue from Group E (Fig-
ure 4B, e...
... immunohistochemical
staining work and analysis, ZXS and LJ conceived the
study, participated in its design and coordination, and
helped draft the manuscript. All authors read and
approved the final ... was
scored independently by two pathologists. If inconsist-
ency existed, a third pathologists served to achieve con-
sensus. In tumor and normal epithelium, the expression
of I...
... ezrin in intercalated duct cells, the tubular complexes of CP and PanINs. (A) Staining of ezrin in the intercalated
duct cells in the paraneoplastic tissues. (B-D) Ezrin-positive staining in ... metastasis was found in the nude
mice treated with the other three cell lines (P > 0.05).
These data indicate that ezrin overexpression can induce
metastasis in vivo in spontane...