... MINIREVIEWNa+/K+-ATPase as a signal transducerZijian Xie and Amir AskariDepartment of Pharmacology, Medical College of Ohio, Toledo, USANa+/K+-ATPase as an energy transducing ion pump hasbeen ... also to the activation ofp42/44 MAPK (also called ERK1/2) through the Ras/Raf/MAPK kinase/MAPK cascade (where Raf is a MAPKkinase kinase and MEK is a MAPK kinase) [29,30].However, the activation ... 198–200.17. Murata, Y., Matsuda, T., Tamada, K., Hosoi, R., Asano, S.,Takuma, K., Tanaka, K i. & Baba, A. (1996) Ouabain-inducedcell proliferation in cultured rat astrocytes. Jpn. J. Pharmacol....