Báo cáo khoa học: Effect of monovalent cations and G-quadruplex structures on the outcome of intramolecular homologous recombination doc

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... affect the association of the substrate with the enzyme in any one of several ways, e.g. through solvation effects on substrates or enzyme active sites and through their effects on the thermodynamic ... (a) the main driving force for the folding is the unfavourable interaction between the osmolyte and the peptide back- bone, and (b) the total contribution of...
Ngày tải lên : 07/03/2014, 00:20
  • 9
  • 547
  • 0
Báo cáo khoa học: X-ray crystallography, CD and kinetic studies revealed the essence of the abnormal behaviors of the cytochrome b5 Phe35fiTyr mutant pdf

Báo cáo khoa học: X-ray crystallography, CD and kinetic studies revealed the essence of the abnormal behaviors of the cytochrome b5 Phe35fiTyr mutant pdf

... while the other one extends into the solvent and does not form any hydrogen bond with the protein atoms. The former propionate displays the conserved conformation in the structures of the Phe35fiTyr ... toward the heme. The mutation from the nonpolar residue Phe35 to the polar residue Tyr35 makes slight changes in the side chain conformation of this residue. Th...
Ngày tải lên : 08/03/2014, 10:20
  • 10
  • 538
  • 0
Báo cáo khóa học: CD38 is expressed as noncovalently associated homodimers on the surface of murine B lymphocytes doc

Báo cáo khóa học: CD38 is expressed as noncovalently associated homodimers on the surface of murine B lymphocytes doc

... stabilize the homodimers (data not shown). These results suggest that the stabilization of CD38 homodimers by crosslinkers depends strongly on the conformation and orientation between the CD38 monomers. It ... expression of CD38 on the plasma membrane and the half-lives of these CD38 mutant proteins on the plasma membrane were significantly reduced. Together, thes...
Ngày tải lên : 23/03/2014, 12:20
  • 10
  • 448
  • 0
Tài liệu Báo cáo khoa học: FGF-2, IL-1b and TGF-b regulate fibroblast expression of S100A8 doc

Tài liệu Báo cáo khoa học: FGF-2, IL-1b and TGF-b regulate fibroblast expression of S100A8 doc

... For other controls, pri- mary or secondary antibodies were omitted. Acknowledgements The authors are obliged to Professor Rolf Howlett for the preparation and donation of wound specimens and Drs ... upstream of the transcrip- tion initiation site, untranslated intron 1 and sequences upstream of exon 1, were used to evaluate activities of deletion constructs after transient...
Ngày tải lên : 19/02/2014, 18:20
  • 17
  • 521
  • 0
Tài liệu Báo cáo khoa học: "An Information-Theory-Based Feature Type Analysis for the Modelling of Statistical Parsing" docx

Tài liệu Báo cáo khoa học: "An Information-Theory-Based Feature Type Analysis for the Modelling of Statistical Parsing" docx

... represents the node, “X” represents the constitute label, the headword or POS of the headword of the node. In the following, the units of PIQ are bits. Conclusion Among the feature types in the same ... possibility to modify the headword) the exact headword information 3.7333 (Y= the headword of the current constitute) Conclusion The predictive informat...
Ngày tải lên : 20/02/2014, 18:20
  • 8
  • 503
  • 0
Báo cáo khoa học: "Constituent-Based Morphological Parsing: A New Approach to the Problem of Word-Recognition" pdf

Báo cáo khoa học: "Constituent-Based Morphological Parsing: A New Approach to the Problem of Word-Recognition" pdf

... Reduplication is the verbal reduplication morpheme. Of interest in this example are regressive Vowel Harmony 4, and, of course, reduplication. The input consists of the stream of segments and a ... cliticization. Also exemplary of the division of duty between the morphophonological parser and the syntactic parser is the dual status of subcategorization...
Ngày tải lên : 08/03/2014, 18:20
  • 8
  • 522
  • 0
Báo cáo khoa học: Energetic coupling along an allosteric communication channel drives the binding of Jun-Fos heterodimeric transcription factor to DNA docx

Báo cáo khoa học: Energetic coupling along an allosteric communication channel drives the binding of Jun-Fos heterodimeric transcription factor to DNA docx

... in concert, their effect is much greater than the sum of the individual parts. Indeed, the effect of the double-alanine substitu- tion of basic residues within the Jun-Fos heterodimer on the ... substitu- tion of all other residues reduces the binding of the Jun-Jun homodimer to DNA by more than one order of magnitude, even though alanine substitution of th...
Ngày tải lên : 22/03/2014, 16:20
  • 15
  • 314
  • 0
Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc

Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc

... indicate that a functional deletion of Synoviolin causes a change in the intracellular trafficking of NCT. Effect of Synoviolin on the production of Ab NCT is one of the essential cofactors of the c-secretase complex. ... most likely that the accumulation of NCT in synoviolin-null cells is a result of the suppression of the degradation of NCT. To further i...
Ngày tải lên : 23/03/2014, 04:20
  • 9
  • 561
  • 0
Báo cáo khoa học: Functional interplay between viral and cellular SR proteins in control of post-transcriptional gene regulation pptx

Báo cáo khoa học: Functional interplay between viral and cellular SR proteins in control of post-transcriptional gene regulation pptx

... binding to a con- sensus element within the long control region of the viral genome, and also functions together with the E1 protein in viral DNA replication [16]. The E2 protein consists of the N-terminal ... inter- actions of SR proteins [1–5]. Reversible phosphoryla- tion of SR proteins is important for assembly and function of the spliceosome and for proper reg...
Ngày tải lên : 23/03/2014, 06:20
  • 10
  • 317
  • 0
Báo cáo khoa học: Direct CIII–HflB interaction is responsible for the inhibition of the HflB (FtsH)-mediated proteolysis of Escherichia coli r32 by kCIII docx

Báo cáo khoa học: Direct CIII–HflB interaction is responsible for the inhibition of the HflB (FtsH)-mediated proteolysis of Escherichia coli r32 by kCIII docx

... ATP-dependence of proteolysis of r 32 by HflB. (Upper) Band corresponding to r 32 on 11% SDS ⁄ PAGE, in the presence or absence of 5 m M ATP. Numbers on the top of each lane indicate the time of digestion ... this mode of antiproteolytic action of CIII a general mode of CIII activity, or does it apply only for CII? We examined the mode of the inhibitory action...
Ngày tải lên : 23/03/2014, 10:20
  • 6
  • 453
  • 0

Xem thêm

Từ khóa: