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ACCELERATING TECHNOLOGY TRANSITION Bridging the Valley of Death for Materials and Processes in Defense Systems potx

ACCELERATING TECHNOLOGY TRANSITION Bridging the Valley of Death for Materials and Processes in Defense Systems potx

ACCELERATING TECHNOLOGY TRANSITION Bridging the Valley of Death for Materials and Processes in Defense Systems potx

... on Accelerating Technology Transition, National Research Council, Washington, D.C., November 24, 2003. ACCELERATING TECHNOLOGY TRANSITION Bridging the Valley of Death for Materials and Processes ... pressure then forces the new technology into production before it is mature enough. The bridge could then break, and the champions and the technology they developed are left in the valley of death ... the beginning in order to ensure meeting the military’s high performance requirements. The challenge in the case of accelerating technology transition in military systems is that the roles in such...
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21st Century Welfare: Presented to Parliament by the Secretary of State for Work and Pensions by Command of Her Majesty pptx

21st Century Welfare: Presented to Parliament by the Secretary of State for Work and Pensions by Command of Her Majesty pptx

... furtherincentivise and encouragehouseholds and familiestomoveinto work and to increase the amount of work they do, by improving the rewards from work at low earnings, and helping them ... promoteresponsibility and positivebehaviour,doingmoretorewardsaving,strengthening the family and, in tandem with improving incentives, reinforcing conditionality; • automate processes and maximiseselfservice,toreduce the scope for fraud,error ... either increasing the incentive to take up work, or to increasing the incentive to increase earnings once in work. Striking a balance between these elements will be important.3. With this in...
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Báo cáo khoa học: The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides pot

Báo cáo khoa học: The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides pot

... RNA. The asterisk indicates the input targetRNA; the arrow indicates the digested product bands. The amount of digested product obtained is indicated at the bottom of the lane s aspercentage of ... of sequence-independent artefacts, most of which are attrib-utable to their ability to bind a number of heparin-bindingproteins [28]. In our search for allele-speci®c inhibitors based on single-nucleotide ... To investigate the nature of the differences in response t o a ntisense ODNs we analyzed the RNase H levels in the cell lines, as RNase H is claimed to be a keycomponent in the mechanism of inhibition...
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Effect of hydrogen peroxide on the destruction of organic contaminants synergism and inhibition in a con

Effect of hydrogen peroxide on the destruction of organic contaminants synergism and inhibition in a con

... l−1) of hydrogen peroxide in the in u-ent, corresponding to OCMR in of 5.33. At these conditions, the degradation of the parent contaminant was 63.1% and the removal of TOC was 38.36%. These minima ... thin film of liquid car-ried by the disk at the interface of the liquid film and the cata-lyst. The maximum volumetric capacity of the reactor vesselis 3.5 l. The catalyst is in the form of composite ... 4-CBA transformation (%), min-eralization to CO2(%) and amount of Cl−released in the solution. On the other hand, a raise of oxygen concentration in the gas phase, and in the absence of hydrogen...
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Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx

Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx

... bycentrifugation at 20 000 g for 30 min at 4 °C. Binding of the fusion proteins to chitin beads via the intein/chitin binding domain, cleavage of the fusion protein (in 20 mMTris/HCl, pH 8.0, ... functions in A. actinomycetemcomitans have anaverage GC content of 48.0% [43]. The GC content of the region essential for the biosynthesis of SPA in the otherserotype strains (b–e) of A. actinomycetemcomitans ... consuming some of the GDP-a-D-mannose, regardless of the addition of the proteins. The peak that appeared at 24.0 min was in agreement with that of authentic NADP+. The reason why the NADP+peak...
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Báo cáo khoa học: Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates potx

Báo cáo khoa học: Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates potx

... Specificinhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and pro-teinase 3: evidence for distinct cleavage sites within the aminoterminal domain of ... substituting Ser for Cys in substrate 12 asa result of the higher electronegative charge of the Oatom of the Ser side-chain compared to that of the sulfur atom in the Cys side-chain; P3¢ Leu for ... Ribbon plot of CG and chymase in irreversible complexes with syn-thetic inhibitors showing ball -and- stick mod-els for the seven residues located in the vicinity of the active site. The molecular...
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the interaction between the frequency of market quotes spread and volatility in forex

the interaction between the frequency of market quotes spread and volatility in forex

... entered in log, rather than in numer-ical, form, and we search for the best fitting transformation of the data using the Box—Cox transformation. Second, in Goodhart and Demos (1990), we argue that there ... dynamics of the VAR are now1.57, 0.86, and 2.13 for the Deutschemark and 1.49, 2.22, and 3.89 for the Yen. Although the systematic dynamics for the number of quotations, for the Yen only, indicates ... predetermined, and reported on another part of the Reuters system, the FXNB page. The stochastic element in such cases is the actual announcement, not the timing of it. In general, the majority of the...
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Quality of care A process for making strategic choices in health systems potx

Quality of care A process for making strategic choices in health systems potx

... to keep in mind the following points. The general evidence-based information on quality is growing, and will increasingly be used – together with other deliberative processes – to inform decision-making ... building a strategy for quality18 In the case of the last of these three situations, the process of decision- making about quality needs to be held in abeyance until there is certainty and ... a proper level of investment in information systems is maintained. Improvements need not depend on high-tech information technology. In some A process for building a strategy for quality...
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The Bottom Line: Accounting for Revenues and Expenditures in Intercollegiate Athletics docx

The Bottom Line: Accounting for Revenues and Expenditures in Intercollegiate Athletics docx

... margins of enrollment, and average cost per student is likely to be a relatively accurate measure of the marginal cost of the student athletes in the program as a whole. Further complicating the ... tuition, then the net cost of athletic aid is simply equal to the size of the student aid award. Otherwise, the average cumulative marginal cost of educating a group of athletes may be either above ... examined to any degree of accuracy. In order to provide some context, however, Table 7 provides profitability data for the schools in the sample assuming student aid costs of zero and including...
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