... ERK1/2.
Recent observations indicate that activation of Raf by
PMA may trigger the same signaling pathway as oncogenic
Raf, or Raf activation by Ras in combination with tyrosine
phosphorylation [30]. ... therapy as an attractive approach for
anticancer treatment. In this context, activation of the
mitogen-activated protein kinase (MAPK)/extracellular
signal-regulated kinase (ERK...
... structural changes of TRAIL at acidic pH,
as characterized in this study, can induce membrane
binding and subsequent membrane leakage. TRAIL could
lead to membrane leakage induced by intrinsic membrane
interaction ... MG-like state not only enhanced
the binding ability to liposomes, but also increased the
release rate of a fluorescent dye, calcein, encapsulated in
liposomes...
... strip was washed
with three changes of 1 · binding buffer over a period of
30 min and autoradiographed.
In vitro
DNase I footprinting analysis
DNase I f ootprinting analysis to identify protected ... 11
Fig. 2. Appe arance of additional factor i nteracting with )148 to )124 region of c-jun after partial hepatectomy. (A) Timeofappearanceofcomplex
C2 after p artial hepatectomy....
... reform in Finland.
Material and methods
A retrospective observational study was conducted in
the EMCC in East and Central Uusimaa, an area of
southern Finland where the EMCC covers about
300 000 inhabitants. ... 506) of
cases the ambulance was dispatched as a low-priority
assignment (code C & D) and the patient was trans-
ported to the hospital with lights and sirens (co...
... provision of
portal -of- entry primary care as well as secondary specialty
care. They noted that diagnostic uncertainty, complexity,
and discriminant variability are characteristic of chest
pain assessment ... pain,
defined most simply as recurrent episodes of unexplained
retrosternal pain in patients lacking a cardiac abnormality
after a reasonable evaluation, is associated...
... not intro-
duced an MET service using the first year of data as baseline
and the second year as comparator. Finally, an additional and
similar analysis was performed for hospitals that had partici-
pated ... Zealand; ANZICS = Australian and New Zealand Intensive Care Society; ANZICS-APD = Australian and New Zealand
Intensive Care Society Adult Patient Database; APD = Adult Patient Data...
... quality assurance survey
Natalie Chahine-Malus, Thomas Stewart, Stephen E Lapinsky, Ted Marras, David Dancey,
Richard Leung and Sangeeta Mehta
Mount Sinai Hospital, Toronto, Ontario, Canada
Correspondence: ... observational study, no attempt was
made to alter the performance of routine CXRs. Informed
consent was not obtained from patients because this study
was part of an ICU quality ass...
...
Research Paper
Prevention of Pleural Adhesions Using a Membrane Containing Polyeth-
ylene Glycol in Rats
Volkan Karacam
1
, Ahmet Onen
2
, Aydin Sanli
2
, Duygu Gurel
3
, Aydanur Kargi
3
, Sami ... experimental studies have
been performed on this subject. Tanaka et al. have
shown that adhesions may be avoided following
thoracotomy by using a hyaluronate-based absorbable
mem...
... or
Dynasan™ 118 along with soyalecithin as the lipid parts. Different formulation parameters;
including type of Dynasan, soyalicithin:Dynasan ratio, drug:total lipid ratio, and polyvinyl al-
cohol ... Yassin AE, Alsarra IA, Alanazi FK, et al. New targeted-colon
delivery system: in vitro and in vivo evaluation using x-ray
imaging. J Drug Target. 2010; 18: 59-66.
31. Alanazi FK,...