... protease domains,
covering the region from Ala-1 to Leu-200 in the
prototype crayfish astacin, from the C. elegans astacins
and selected other astacin family members were aligned
using
CLUSTAL
[32] ... named after
their occurrence in complement components C1r/C1s,
embryonic sea urchin protein Uegf, and BMP-1 [62].
These domains may be involved in calcium-binding and
prote...
... starting
points for invasion. The concerted process of opening
of the initial double strand and the annealing of the
new duplex finally results in either the replacement of
the original strand or the ... repulsive interactions
within the RNA molecule. The protein thereby
smooths the folding energy landscape. The direction of
the RNA folding reaction (either annealin...
... consonantal doubling rules
in the inflection of English verbs
C. The determination of word-breaking rules as used
in end-of -the- line practices in type composition
D. The determination of parts-of-speech ... have the
property that the internal-consonant string is an ad-
missible initial-consonant string. The words in Class
III
have the mirror image property that...
...
extracted by the methods of the linguist than by
those of the statistician.
The indeterminacy which does exist in lan-
guage is the indeterminacy which arises from
the mapping of a continuous ... Compression
In large measure the coding problems arising
in MT and in library work are the same as
those occurring in other branches of communi-
cation engineering....
... (NFTs) in the brains of
people with DS ⁄ AD than in the brains of people with
sporadic AD (Fig. 2) [19]. DYRK1A phosphorylates
tau protein at the sites that are phosphorylated in AD.
In NFTs, tau protein ... DYRK1A
phosphorylation of tau protein at 11 sites [20,22,43];
the DYRK1A-stimulated, several-fold increase in the
rate of tau protein phosphorylation by GSK-3b...
... alone. The kinase-deficient mutant,
OXI1
K45R
, in which the lysine residue of the ATP bind-
ing domain is mutated to arginine, still interacted with
PTI1-4. These data indicate that the kinase ... of the input was loaded on to the gel
and represents the amount of HIS-tagged proteins used for the
assay. The in vitro binding assays were repeated twice using
recombinant pro...
... with
the N-terminal domain, MA, associated with the inner
layer of the viral membrane, and the remaining
domains forming the innermost protein layers accor-
ding to their positions in Gag: MA, CA-NTD,
CA-CTD, ... Spain
Introduction
During HIV-1 morphogenesis [1,2], the capsid protein
(CA; or p24) participates in two distinct assembly
events. The first occurs inside the...
... of both the CAI peptide and a-helix 9
of CTD during formation of the peptide–
protein and protein protein complexes.
These NMR experiments also allowed the determina-
tion of the CTD binding site. ... 6110–6117 ª 2009 The Author Journal compilation ª 2009 FEBS
Gag polyprotein, yields the matrix protein (MA),
the capsid protein (CA), the nucleocapsid protein
(NC) and...
... employing microscopic lipid-binding con-
stants has previously been taken to explain the enhancement of agonist
binding to the nicotinic acetylcholine receptor by general anaesthetics in
terms of the ... simulate the unknown
narcotic receptor(s) of tadpoles, all other parameters
characterizing the nAChR lipid ⁄ protein interface
remaining constant. The initial analysis assumes...
... multispan-
ning membrane proteins, we have investigated the mechan-
ism of how the sensor kinase protein KdpD inserts into the
membrane. We found that KdpD inserts into the membrane
independently of the ... KdpD-N. The protein
was not accessible to the externally added proteinase K,
indicating that it remains in the cytoplasm. Intriguingly, the
formation of the dimer...