Báo cáo khoa học: X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-b-D-galactopyranoside pdf

Báo cáo khoa học: X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-b-D-galactopyranoside pdf

Báo cáo khoa học: X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-b-D-galactopyranoside pdf

... protein. This kind of protein is exemplified by the Thermus thermophilus protein, PDB entry 2B3B [28]. The mode of binding the monosaccharide is completely different in terms of orientation of the ... calcium site of domain 2 was described earlier, and tight binding of the ion was shown to con- tribute to the integrity of the protein structure [17,22]. The sod...
Ngày tải lên : 23/03/2014, 04:21
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Báo cáo khoa học: Crystal structure of a designed tetratricopeptide repeat module in complex with its peptide ligand pot

Báo cáo khoa học: Crystal structure of a designed tetratricopeptide repeat module in complex with its peptide ligand pot

... conformation. At the N-terminus of the peptide, the alignment diverges more, with the major difference being that the N-terminal Met is signifi- cantly further away from the binding cleft in the CTPR390–MEEVD ... complexes are in the location of the peptide chains relative to the pro- tein (Fig. 5A). The Hsp90 peptide is located in the CTPR390 concave clef...
Ngày tải lên : 29/03/2014, 08:20
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Báo cáo khoa học: Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor potx

Báo cáo khoa học: Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor potx

... calculations for the two interacting molecular surfaces, performed with the program sc from the ccp4 suite [27]. The obtained sc value of 0.400 indicates weak binding of the two entities of the RATE. Therefore, ... of RNase molecules on the cell surface), thereby favoring their endocytosis [19]. The stoichiometry of RI binding to RATEs and the role of the R...
Ngày tải lên : 22/03/2014, 16:21
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Tài liệu Báo cáo khoa học: Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-D-glyceric acid Selective inhibition by structure-based design docx

Tài liệu Báo cáo khoa học: Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-D-glyceric acid Selective inhibition by structure-based design docx

... elsewhere on the pathway of the multistep catalysis, where the OH inter- actions with residues of the active site are not required. Using information on the 3D structure of the enzyme– inhibitor complex, ... structures [24]. Parallel studies of these effects allowed identification of the specific interactions between the inhibitors and the proteins. In the a...
Ngày tải lên : 20/02/2014, 02:21
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Báo cáo khoa học: Solution structure of Cu6 metallothionein from the fungus Neurospora crassa pptx

Báo cáo khoa học: Solution structure of Cu6 metallothionein from the fungus Neurospora crassa pptx

... data. The accu- racy of the structure calculated without these constraints is, however, supported by the similarities of the 800 MHz structures of the a-domain of mouse MT1 compared to the one ... to the average minimized structure, for each set of reintroduced long-range NOEs. Determining the deviation of the generated structure with a reduced number of...
Ngày tải lên : 23/03/2014, 13:20
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Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt

Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt

... The bind- ing of the ®rst CN ± ligand to the iron was thus more easy in the hydrophobic binding pocket of the antibody than the binding of the second one, most probably because of the steric hindrance ... substituents of the meso-phenyl rings being recognized by th e side chains of amino acids of the antibody [36]; (b) in the case of 13G10, one carbox...
Ngày tải lên : 21/02/2014, 03:20
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Báo cáo khoa học: "Minimalist Parsing of Subjects Displaced from Embedded Clauses in Free Word Order Languages" ppt

Báo cáo khoa học: "Minimalist Parsing of Subjects Displaced from Embedded Clauses in Free Word Order Languages" ppt

... those in the “input queue,” and if not, shifting a word from the input queue onto the processing buffer. The distinction is marked, in our notation, by a |: the words and trees before | are in the ... if there is another displaced item in the tree containing the original CH that is compatible with the UNCH feature but displaced from some other phrase. This requ...
Ngày tải lên : 23/03/2014, 19:20
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Tài liệu Báo cáo khoa học: Crystal structure of an ascomycete fungal laccase from Thielavia arenaria – common structural features of asco-laccases ppt

Tài liệu Báo cáo khoa học: Crystal structure of an ascomycete fungal laccase from Thielavia arenaria – common structural features of asco-laccases ppt

... gives the solvent access to the trinuclear centre. However, the channel is blocked by the C-terminal end of the amino acid chain in MaL ⁄rMaL [25,33]. Similarly, in the structure of TaLcc1, the ... DSGL as the last four amino acids penetrating into the channel. The C-terminal processing has been reported for asco-laccases of different origins [37–39]; furthermo...
Ngày tải lên : 14/02/2014, 18:20
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Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt

Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt

... determined the X-ray crystal structure of a truncated form of importin-a lacking the importin-b binding domain, bound to a CLIC4 NLS peptide. The NLS peptide binds to the major binding site in an extended ... cargo binding sites, referred to as the major and minor binding sites [1]. These sites are located in the concave face of the protein near regions of invari...
Ngày tải lên : 14/02/2014, 19:20
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Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf

Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf

... metal-binding site at the interface of the two domains, which consists of four side chains: two (His31 and His79) from the N-terminal domain and two (Asp165 and His169) from the C-terminal domain ... focus on the coordination of the metal cofactor in the active site as well as the changes it experiences in response to different metal cofactors. Finally, by compar...
Ngày tải lên : 14/02/2014, 22:20
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