Báo cáo khoa học: Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily ppt

Báo cáo khoa học: Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily ppt

Báo cáo khoa học: Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily ppt

... motif of FhaC. The VRGY tetrad is highly conserved in the TpsB family and, in FhaC, it is located at the tip of L6 reaching the periplasm. Replacement by Ala of the invariant Arg dramatically affects ... against a major con- formational change of the loop. Structural data are available in the Protein Data Bank under the accession numbers 2QDZ (FhaC WT ) a...
Ngày tải lên : 23/03/2014, 03:20
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Báo cáo khoa học: Functional genomics by NMR spectroscopy Phenylacetate catabolism in Escherichia coli docx

Báo cáo khoa học: Functional genomics by NMR spectroscopy Phenylacetate catabolism in Escherichia coli docx

... Consequently, the PaaF and PaaH proteins appear to catalyse reactions in the downstream part of phenylacetate degradation. In the absence of the PaaF and PaaH proteins, catabolism of phenylacetate is ... suggests a role for the PaaG and PaaZ proteins early in the pathway. The other major finding is that C 6 dicarboxylic acids formed later in the pathway are deri...
Ngày tải lên : 23/03/2014, 18:20
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Báo cáo khoa học: Tec family kinases Itk and Rlk⁄ Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates pot

Báo cáo khoa học: Tec family kinases Itk and Rlk⁄ Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates pot

... Schwartzberg National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA Introduction Among the key players in intracellular signaling in lym- phocytes are the Tec family kinases ... cascade of signal- ing events initiated by the activation of the Src-family kinase Lck, which phosphorylates immunoreceptor tyrosine activation motifs on the int...
Ngày tải lên : 28/03/2014, 22:21
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Tài liệu Báo cáo khoa học: Functional and structural analyses of N-acylsulfonamidelinked dinucleoside inhibitors of RNase A ppt

Tài liệu Báo cáo khoa học: Functional and structural analyses of N-acylsulfonamidelinked dinucleoside inhibitors of RNase A ppt

... Discussion Sulfonimides as inhibitors of RNase A We began by determining the ability of three backbone analogs of RNA to inhibit catalysis by RNase A. These analogs have a simple polyanionic backbone with neither a ... USA Introduction Upon catalyzing the cleavage of RNA, RNases operate at the crossroads of transcription and translation. Bovine pancreatic RNase A (EC...
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Functional characterization of an orphan cupin protein from Burkholderia xenovorans reveals a mononuclear nonheme Fe2+-dependent oxygenase that cleaves b-diketones ppt

Tài liệu Báo cáo khoa học: Functional characterization of an orphan cupin protein from Burkholderia xenovorans reveals a mononuclear nonheme Fe2+-dependent oxygenase that cleaves b-diketones ppt

... PCR with GAGCGG CATATGGA AATCAAACCGAAGGTTCGCGA and GAGCGG CATA TGGAAATCAAACCGAAGGTTCGCGA as the forward and reverse oligonucleotide primers, respectively. The primers were designed to introduce ... coordi- nated by an oxygen donor group derived from the carboxylate side chain of either a glutamate or an aspartate. The apparent conflict of this finding with the absence of a c...
Ngày tải lên : 18/02/2014, 06:20
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Báo cáo khoa học: Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus pot

Báo cáo khoa học: Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus pot

... staphy- lococcal adhesins, comprising an N-terminal region that binds fibrinogen and elastin, and a C-terminal domain that interacts with fibronectin. The C-terminal domain of fibronectin-binding ... FEBS Monoclonal antibodies against FnBRs of FnBPB A panel of mouse mAbs was produced against the recombinant repetitive region of FnBPB. Analysis of mAbs binding to the recombina...
Ngày tải lên : 06/03/2014, 22:21
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Báo cáo khoa học: Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan ppt

Báo cáo khoa học: Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan ppt

... are parasitic protozoa belonging to the order Kinetoplast- ida. They are causative agents of several highly disab- ling and often fatal diseases, including African sleeping sickness, Chagas disease ... exhibits another variation in the first steps of the pathway. C18 FAs are elongated to C20, and then a D8 desaturase produces the same kind of C20 FAs that will be the substr...
Ngày tải lên : 07/03/2014, 12:20
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Báo cáo khoa học: Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening docx

Báo cáo khoa học: Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening docx

... (5¢-CGTCAAGGAGAAAAAACCCCGGATCT AAAAAATGGAGCGAAGGAACCACAG-3¢) and (5¢-AG CTGCCTGCAGGTCGACTCTAGAGGATCCTAACCAA TTTTGCTGCC-3¢); for OR17-40 (5¢-CGTCAAGGAG AAAAAACCCCGGATCTAAAAAATGGAGCAGAAAC TCATCTCTGAAGAGGATCTG-3¢) and (5¢-GCATG CCTGCAGGTCGACTCTAGAGGATCTCAAGCCAGT GACCGCCTCCC-3¢); ... coding sequence, using primers (5¢-CGTCAAGGAGAAAAAAC CCCGGATCTAAAA AATGGAGC AGAAA CTCATCTC TGAAGAGGATCTG -3¢) and...
Ngày tải lên : 07/03/2014, 16:20
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Báo cáo khoa học: Functional implications of pigments bound to a cyanobacterial cytochrome b6f complex potx

Báo cáo khoa học: Functional implications of pigments bound to a cyanobacterial cytochrome b6f complex potx

... isolated from strains retaining CrtO, this carotene appears to be in the all-trans form. A characteristic difference in the carotenoid content of the PS1-less mutant and the derived strain lacking echinenone ... Koyama Y, Takii T, Saiki K & Tsukida K (1983) Con- figuration of the carotenoid in the reaction center of photosynthetic bacteria. 2. Comparison of the...
Ngày tải lên : 07/03/2014, 16:20
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Báo cáo khoa học: Functional fine-mapping and molecular modeling of a conserved loop epitope of the measles virus hemagglutinin protein pdf

Báo cáo khoa học: Functional fine-mapping and molecular modeling of a conserved loop epitope of the measles virus hemagglutinin protein pdf

... been partially induced against the linear isoform of the HNE peptide. Although the binding pattern may be somewhat blurred by these antibodies and by the polyclonal nature of the sera, the importance ... [32]. Evenasmallsidechaininposition388wouldresultinsteric hindrance with the main-chain nitrogen atom of K389, damaging the shape of the loop. The above spatial...
Ngày tải lên : 08/03/2014, 08:20
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