The Evolution from Protein Chemistry to Proteomics Basic Science to Clinical Application potx
Progestins and the Mammary Gland From Basic Science to Clinical Applications pdf
... shown to exert their effects throughligand-activated steroid receptors in the mammary epithelium. Approx-imately 10%–15% of the cells within the epithelium coexpress oestro-gen receptor alpha ... cells from this subpopulation had the ability to produce the normal hetero-geneous structure of the gland, suggesting that these cell markers arenot sufficient to completely mark the SC (Shackleton ... Consequently, the CSCs survive and are likely to be responsible for recurrence of the carcinomas. It is therefore es-sential to develop therapies that target the CSC itself. To aid the devel-opment...
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Methamphetamine Addiction From Basic Science to Treatment pptx
... wherewithal to adhere to these treatment regimens, further increas-ing the public health imperative to include MA treatment strategies in the management of these conditions.MA use is against the law. ... understanding of the effects of the drug on the user’s brain and modify their interactions with, and expectations of, their children accordingly. Others may encounter, for the first time and in the face ... moved east toward the end of the 1990s (Kurtz & Inciardi, 2003). The middle stages of the epidemic saw the increase in small-time “cooks” in the United States who used over -the- counter...
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TEXTBOOK OF Hepatology From Basic Science to Clinical Practice doc
... the right from the midline of the anteriorbody wall and the caudal surface of the anterior portion of the diaphragm. Lying in the free edge of the falciform ligament, from the umbilicus to the ... lobes. These landmarks together are customarily con-sidered to form the letter H, and the parts of the liver between the uprights of the letter are the quadrate and caudate (spigelian)lobe. The ... references, to have to search at the end of the chapter to find the original sources. We therefore decided to usemainly short ‘text references’ to enable readers to decide quicklyif they are already...
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RNA Interference Technology FROM BASIC SCIENCE TO DRUG DEVELOPMENT ppt
... powerful tool that has been used to inhibit gene func-tion either by increasing the destruction of mRNA corresponding to the gene,or in some cases, by inhibiting the transcription of the gene or the ... oligoribonucleotides into cells, the stability,concentration, and toxicity of the oligoribonucleotides, and the length of time the oligoribonucleotides remain in the cells. These are challenging ... BiochemistryUniversity of Bristol The School of Medical SciencesUniversity Walk, Bristol BS8 1TDUKE-mail: p.kuwabara@bristol.ac.ukEric Lader, PhD.QIAGEN, Inc.19300 Germantown RdGermantown,...
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MicroRNAs FROM BASIC SCIENCE TO DISEASE BIOLOGY docx
... have been char-acterized from different animals such as the worm Caenorhabditis elegan s,theflyDrosophila, and mammals including the human, the mouse and the rat. The totalnumber of miRNAs in ... regulators in plants and animals (Bartel,2004; Kim, 2005). Among all the categories of endogenous small RNAs, these tinyRNAs have received the most notice (Sontheimer and Carthew, 2005). They ... plant for functional genomic research. It is therefore interesting to * Author to whom correspondence should be addressed.MicroRNAs: From Basic Science to Disease Biology, ed. Krishnarao Appasani....
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Tài liệu HEMATOPOIETIC GROWTH FACTORS IN ONCOLOGY BASIC SCIENCE AND CLINICAL THERAPEUTICS pptx
... DevelopmentHematopoietic Growth Factors in Oncology: Basic Science and Clinical TherapeuticsEdited by: G. Morstyn, M. A. Foote, and G. J. Lieschke © Humana Press Inc., Totowa, NJ6Erythropoietic Factors Clinical ... addition to being used directly to increase neutrophil counts, rHuG-CSF can beused to mobilize precursor cells from the bone marrow to the blood, where they can bemore easily collected. Although the ... unclearwhether this is related to rHuG-CSF use or to a natural progression of the disease thatis only expressed when rHuG-CSF allows the patients to survive long enough to develop symptoms (100,101).4....
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Tài liệu Nutrition in Pediatrics Basic Science and Clinical Applications - THIRD EDITION docx
... to the severity of the zinc depletion, the clinical sequelaeappear to depend on other factors, including the speed ofonset and associated clinical and dietary factors such as protein- energy malnutrition.Decreased ... asindicators of the adequacy of the test amino acid.81Thismethod is based on the idea that the nutritional indispens-ability of an amino acid is attributable to the inability to synthesize ... selected or retained based on their expertise in the topic of their chapter and their willingness to provide the most updated views on the subject.In general, we believe that the third edition will...
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VIRAL ONCOLOGY Basic Science and Clinical Applications pot
... appears to be important, specifi cally in oropharyngeal cancers, such as the tonsils and the base of the tongue. The tonsils mimic the cervix and the anal verge as sites of metaplastic epithelium, ... These allow differentiated epithelial cells to continue to divide when they otherwise would not. They no longer recognize signals from DNA damage through the p53 pathway to go through apoptosis ... tandem with E6 to drive differentiated epithelial cells to continue to divide. E7 is known to bind to many endogenous cell cycle proteins, including pocket proteins retinoblastoma protein (Rb),...
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Textbook of Sports Medicine Basic Science and Clinical Aspects of Sports Injury and Physical Activity pot
... hope the reader of this book will share the research dreams, the clinical interest, and the enthusiasm in relation to the sports medicine topics with that of the authors and the entire editorial ... in their capacity to both store energy and to ex-tract and utilize oxygen. With regards to endurancecapacity, humans are still left with the fact that the sizeof the heart relative to the ... causedby inhibitory feedback from sensory group I and II af-ferents. Sensory Ib afferents from Golgi organs locatedin the muscle–tendon unit converge onto the entiremotoneuron pool together with...
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Tendon Injuries Basic Science and Clinical Medicine pdf
... hand and the flexor digitorum longus in the foot. The oblique fibers of the vastus medialis arise from the tendon of the adductor magnus. The obliquefibers of the vastus lateralis arise from the iliotibial ... in their contribution to the Achilles tendon andin the extent of their fusion. The soleus varies from 3 to 11cm, and the gastrocnemius from 11 to 16cm. As the tendon descends it twists, and the ... between the origin and insertion. The range of motion of a musculotendinous unit and the force applied to the tendon determine the orientationof the fibers, relative to the axis of the tendon.The...
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