Báo cáo khoa học: Netropsin interactions in the minor groove of d(GGCCAATTGG) studied by a combination of resolution enhancement and ab initio calculations pot
... interactions
FEBS Journal 272 (2005) 3531–3541 ª 2005 FEBS 3533
Netropsin interactions in the minor groove
of d(GGCCAATTGG) studied by a combination of
resolution enhancement and ab initio calculations
Kristof ... (NAE) was
investigated by evaluating the interaction energies and
hydrogen positions of the end fragment and the bases
of bas...
... proteins
contain an N-terminal SAP domain, an SP-RING domain, a SUMO
interaction motif (SIM) and a C-terminal domain (CTD) [39]. (B) Pc2
contains an uncharacterized E3 domain, a ubc9 binding domain and
a ... likely that ubc9 and the UFD of
uba2 interact at the a1 region. (b) The region below
the a1 helix consists mainly of the N-terminal exten-
sion of a1 and...
... fat bodies were collected and RNA lev-
els were analyzed using qPCR. Transcript abundance values for AaEcRA, AaEcRB, AaUSP -A, AaUSP-B, AaE7 5A (A) , AaHR3, AaHR4, AaE78,
AaHR39, AaHR78 (B) and AabFTZ-F 1A, ... biological repli-
cates were analyzed, and Fig. 2 depicts the profile
matching both replicates.
An increase in transcript abundance for AaEcRA,
AaEcRB, AaE7 5A, AaE75B, AaE75...
... m
I
,
m
t2
and m
f
are m-values associated with each of the
identifiable states of the folding pathway and relate to
the amount of solvent-exposed surface area in each of
these states (see Materials and ... general.
Having now established this unequivocally, the
above findings are of particular importance in our abil-
ity to engineer increased protein–protein interac...
... indicat-
ed. The presence of AO, SsaDH and CH
3
-4-aminobutyrate as
substrate were required for maximal activity. In the absence of AO
there was no NADPH produced and with AO, SsaDH and 4-amino-
butyrate ... FEBS
Final steps in the catabolism of nicotine
Deamination versus demethylation of c-N-methylaminobutyrate
Calin-Bogdan Chiribau
1
, Marius Mihasan
1,2
, Petra Gan...
... contains a large number of gaps (Table 1). In the
case of GGA1, there are 9847 gaps remaining. There-
fore, applying the segmentation algorithm to each frag-
ment will fail to unveil the characteristic ... var-
ious intervals of halting parameter values. The Y-axis in the upper
panel shows the cumulative percentage of the values at or below
each interval. The Y-a...
... partic-
ularly facilitated in the brain, as the brain contains
large quantities of oxidizable lipids and metals, and,
moreover, has fewer antioxidant mechanisms than
other tissues [8].
Free radicals ... GSH).
Pilocarpine-induced SE produces several changes in
variables related to the generation and elimination of
oxygen free radicals in adult rats [18,30]. An increase
i...
... 2-cyclohexen-1-one. The H18 1A and
H18 4A enzymes retain activity in reductive and oxidative half-reactions,
and thus do not play an essential role in catalysis. Ligand binding and
catalysis is not substantially ... bond in
close proximity of the N5 atom. A putative flipping
motion of the progesterone molecule along an axis
parallel to the FMN plane aligns the C...
... and the
arrowheads indicate the position of Ga
q
and
Ga
16
. The molecular mass standards are
indicated. The arrow indicates the position
of some unspecific bands.
Proteasome degradation of G
q
proteins ... Johansson et al. Proteasome degradation of G
q
proteins
Proteasome involvement in the degradation of the G
q
family of Ga subunits
Bente B. Johansson, Laura...