Báo cáo khoa học: The common phospholipid-binding activity of the N-terminal domains of PEX1 and VCP/p97 doc

Tài liệu Báo cáo khoa học: DNA strand exchange activity of rice recombinase OsDmc1 monitored by fluorescence resonance energy transfer and the role of ATP hydrolysis pptx

Tài liệu Báo cáo khoa học: DNA strand exchange activity of rice recombinase OsDmc1 monitored by fluorescence resonance energy transfer and the role of ATP hydrolysis pptx

... between donor and acceptor dyes, will therefore unveil the sta- tus of physical union and separation of complementary strands during renaturation and strand exchange, respectively, and thereby assesses the ... monitor the time course of renaturation and strand exchange activ- ities of OsDmc1. The renaturation activity was found to be stimulated in the presence o...
Ngày tải lên : 19/02/2014, 07:20
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Tài liệu Báo cáo khoa học:Symmetric fluoro-substituted diol-based HIV protease inhibitors Ortho-fluorinated and meta-fluorinated P1/P1¢-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacyy docx

Tài liệu Báo cáo khoa học:Symmetric fluoro-substituted diol-based HIV protease inhibitors Ortho-fluorinated and meta-fluorinated P1/P1¢-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacyy docx

... the antiviral activity and retained the binding efficacy. The flexibility of the target molecule complicates the prediction of an effect caused by a modification on the inhibitor and necessitates structural ... surf ace and has polarity d ifferences. This is documented by the threefold improvement in activity of inhibitors 2 and 6 against the triple mutant M46I,...
Ngày tải lên : 19/02/2014, 16:20
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Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... preferential hydration of the protein domain is the driving force of protein stabiliza- tion or folding [3,4]. Furthermore, the effect of osmolytes on the functional activity of an enzyme has also ... published elsewhere. We have therefore measured the thermodynamic parameters of RNase-A in the presence of these amino acids and amino acid derivatives, and values...
Ngày tải lên : 07/03/2014, 00:20
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Báo cáo khoa học: Akt-dependent phosphorylation negatively regulates the transcriptional activity of dHAND by inhibiting the DNA binding activity pdf

Báo cáo khoa học: Akt-dependent phosphorylation negatively regulates the transcriptional activity of dHAND by inhibiting the DNA binding activity pdf

... phosphorylation of dHAND decreased the transcriptional a ctivity of dHAND/E47 heterodimer. Fig. 6. The effects of A kt expression on the transcriptional activity of dHAND. (A) AU5-d HAND, -dHAND-Ala-X, -dHAND-Ala, ... phosphorylation of these sites might affect the DNA binding and/ or dimerization activities of dHAND. We first analyzed the effect of phosphorylation on...
Ngày tải lên : 07/03/2014, 16:20
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BÀI BÁO CÁO KHOA HỌC TẠI BẮC KINH ATCM 2009 THE SCIENTIFIC REPORT IN BEIJING - CHINA

BÀI BÁO CÁO KHOA HỌC TẠI BẮC KINH ATCM 2009 THE SCIENTIFIC REPORT IN BEIJING - CHINA

... second number then we multiply two numbers together • Press the = key. Answer : 2.232710263 We continue to delete the digit 2 at the first number and the digit 7 at the second number then we multiply ... 1 The number contains the end two digits are digit 1 The number contains the end three digits are digit 1 The number contains the end four digits are digit 1 Answer...
Ngày tải lên : 21/10/2013, 16:11
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Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc

... (black) and sucrose (grey). Doc. S1a. Model structure of C24. Doc. S1b. sbml format of model structure of C24. Doc. S2a. Model structure of Rsch. Doc. S2b. sbml format of model structure of Rsch. Doc. ... concentration c A (t) and the rate constant k. The model code and a detailed description of the model structure are provided in Docs S1a, S1b, S2a,b and S3)....
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma pptx

Tài liệu Báo cáo khoa học: Mouse recombinant protein C variants with enhanced membrane affinity and hyper-anticoagulant activity in mouse plasma pptx

... cooperative binding of Ca 2+ turns the N-terminal part of the Gla domain inside out, exposing the hydrophobic x-loop to solvent and burying the majority of the Gla resi- dues. Of the seven Ca 2+ , the majority ... of bovine prothrombin fragment 1 in complex with Ca 2+ [41], the 10 ⁄ 12 site resides near the x-loop and the linear array of bound calcium ion...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: KCNE4 can co-associate with the IKs (KCNQ1–KCNE1) channel complex ppt

Tài liệu Báo cáo khoa học: KCNE4 can co-associate with the IKs (KCNQ1–KCNE1) channel complex ppt

... membrane. Together, our findings contribute to the understanding of the role of KCNE4 as a potentially important regulator of KCNQ1 and other K V channels. Results Characterization of KCNE4 antibody A ... KCNE proteins, and the overlapping expression patterns of these subunits [22], there may be multiple and diverse KCNE–KCNQ1 interactions within the same cells or tissu...
Ngày tải lên : 18/02/2014, 17:20
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Tài liệu Báo cáo khoa học: Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11⁄hippostasin ppt

Tài liệu Báo cáo khoa học: Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11⁄hippostasin ppt

... RT-PCR to study the tissue-specific use of each promoter. We show the translation initiation site of isoform 2 and different intracellular distribution of isoforms 1 and 2, and discuss the regulatory ... part of isoform 2 mRNA. The third exon, exon 1c, extended from +1379 to +1454. The noncoding exons of exons 1a and 1c contributed to the 5¢ nontranslated region...
Ngày tải lên : 19/02/2014, 06:20
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Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx

Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx

... alog (pH ) pK a2 ), Lim1 is the lower limit of the curve, Lim 2 is the middle limit of the curve and Lim 3 is the upper limit of the curve. Stopped-flow kinetic studies of the oxidative half-reaction ... group on Trp57 of the small subunit to a carbonyl group, and (c) insert a second oxygen atom into the TTQ ring [11]. The essential nat- ure of some of th...
Ngày tải lên : 19/02/2014, 07:20
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