... of Science, Tohoku University, Sendai, Japan;2Fukushima Medical University, Fukushima,Japan;3Hiroshima Prefectural Women&apos ;s University, Hiroshima, Japan;4PHP Laboratory for Molecular ... blood cells, resulting in hemolyticanemia.MATERIALS AND METHODSChemicalsSodium p-hydroxymercuribenzoate (p-MB) was from Sig-ma. Mes, Mops, Hepes, Tris and Caps for buffer systems,2-mercaptoethanol, ... aproton-relay mechanism [6,7].In our previous paper [8], such a nucleophilic displace-ment mechanism w as successfully applied to d etailedpH-dependence studies of the kfand k s values, both forthe...