Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc
... SRP
pathway, the targeting pathway that is exploited by integral
inner-membrane proteins. Together, these data indicate
that the helix breaker in cleavable signal sequences prevents
recognition by ... The presence of a helix breaker in the hydrophobic core
of signal sequences of secretory proteins prevents recognition
by the sign...
... via the motor cortex and pyramidal tract to the
ventral brain stem. The involuntary path is comprised
of amygdala, thalamic, hypothalamic, and subtha-
lamic areas, in addition to the dorsal ... to be in the range of ten to
twenty-five laughs in one day, and on the situational
laughter scale, a rating of four to seven. Clinically,
laughter history can be obtained...
... responsible for the
downregulation of catalytic activity of a subunit toward
calmodulin and for the activation by polybasic compounds.
The examination of amino-acid alignment in the acidic
region of three ... protein -A Sepharose,
washed and separated by SDS/PAGE. The immunostaining
of Western blot was performed by commercially available,
high affinity anti-(b-gal...
... thermophilic bacteria are usually
stable to heat and chemical denaturants, indicating that they
must have most of the determinants of protein stability.
Initial clues to the relationship between protein ... protein into an artificial one with stability similar
to that of the natural thermophile by replacing a few amino-
acid residues. Therefore, the thermophilic character of...
... Proteins exhibiting ribonuclease
activity appear as colourless bands after proper destaining
treatment. Hydrolysis of adenylyl(3
0
!5
0
)adenosine (ApA)
by a- sarcin and the mutant variants was ... and base on the catalysis by a- sarcin [19,20],
rendered proteins with no detectable activity against ApA
[20]. Cleavage of ApA by a- sarcin is a low-specificity
reaction requ...
... feature allows HA to
maintain conformational stiffness and to retain water.
One gram of HA can bind up to 6 L of water [6]. As a
physical background material, it has functions in
space filling, ... with a mean depth of 8.3 mm of the
infra-bone defects, as revealed by intra-operative probes. Data were obtained at baseline
before treatment and after 10 days, and subsequen...
... different erythrocyte age/density fractions obtained by
isopycnic centrifugation on a Percoll gradient. Methyl esterification in
intact erythrocytes was assayed by incubating them in the presence of
[
3
H]methionine ... erythrocyte
population [5]. These observations indicate that biochemical
alterations that occur naturally during erythrocyte ageing
are part of the mechanism...
... of a ouabain-binding antibody
lowered the NaCl-dependent rise in the amount of ACE
mRNA, which may indicate that the increase in ACE
mRNA is secondary to the activation by brain ÔouabainÕ
[73]. ... activity of the ACE in hypothalamus and pons of Dahl
salt-sensitive rats without a parallel increase in angioten-
sin II levels. Chronic blockade of brain Ôouabain...
... level of Raf/
MAP kinase [3]. Human sprouty family members are
assumed to exert a function similar to inhibitors of the ras/
MAP kinase signaling pathway that are induced by
activated ras itself, ... without any
substantial open reading frame. The longest transcript
(7 kb) harbors five polyadenylation sites (two AATAAA,
and three AATTAAA), nine ATTTA sequences [23], two
Alu-repea...
... accepting
the fee, the doctor has a contractual duty to provide a
Abstract
Medical practitioners have a duty to maintain a certain
standard of care in providing their services. With
critical care ... perform a vaginal hysterectomy that
was beyond the capacity of the registrar in question. As a
result of poor surgical skills, the patient’s fallopian tube
w...