Báo cáo khoa học: The organotellurium compound ammonium trichloro(dioxoethylene-o,o¢)tellurate reacts with homocysteine to form homocystine and decreases homocysteine levels in hyperhomocysteinemic mice pptx
... decreased total homocysteine but not total
cysteine levels in hyperhomocysteinemic mice
The ability of AS101 to inhibit homocysteine was next
tested in vivo. C57bL ⁄ 6 mice were divided into four
experimental ... ammonium
trichloro(dioxoethylene-o,o ¢)tellurate reacts with
homocysteine to form homocystine and decreases
homocysteine levels in hyperh...
... specific interactions
between cis-acting elements mainly localized in the
UTRs of the transcript and the trans-acting factors
(RNA-binding proteins and noncoding regulatory
RNAs) that bind to these ... SF2 to
induce the destabilization of the mRNA encoding
PKCI-related protein by direct binding to a purine-rich
sequence present in PKCI-r mRNA 3¢ UTR [15]. On
the other...
... literature: the dominant polymorph
a-chitin (antiparallel packing of the chitin chains);
b-chitin (parallel packing of the chitin chains); and the
minor polymorph c-chitin (mixture of parallel and
antiparallel ... to gain access to and degrade individual
polymer chains. First, the chains are degraded by both
endochitinases, that attack the chitin chain randomly,
and ex...
... determined. In
all five cases, the two RRMs and the interdomain lin-
ker cooperatively bind RNA providing high affinity
and specificity. In the free forms of sex-lethal and
nucleolin, the linkers ... and ⁄ or as a hydrogen bond donor interacting
with the carbonyl oxygen of the protein backbone [38].
Other parts of the RRM domain, such as the b
2
-strand
and the...
... article with title “Franz Kafka” and
to expect the answer in the text on that page. For
the question “Who invented the automobile?” on
the other hand, it is more reasonable to search the
information ... intention
behind this mode of presentation is to prominently
display the piece of information the user is most in-
terested in, but also to present context inf...
... the interaction between
actin and myosin in the actomyosin complex [19,20]. The
acetylation of the N terminus removes a positive charge
and increases the interaction between actin and myosin
compared ... maintained a normal c-actin
distribution within the cell in contrast with the parental KB
cells [9] whereas the ectopic expression of p20 BAP31
(lacking the 8 kD...
... which forms one of the internal borders of the
ligand-binding pocket. The side chain of W318 itself is
directed into the ligand-binding pocket. Thus, the trypto-
phan is in a position to potentially ... into
the ligand-binding pocket cavity (and not interacting with secondary recep-
tor structures or extending to the receptor surface to interact with coactiva-
tors,...
... scaling factor
determined by Fourier self-deconvolving the spectra, deter-
mining the tyrosine band a rea ratios at 1518 cm
À1
,andthen
using this as the scaling factor for subtracting the original
spectra ... baseline-correction was not
used, the first value in the band was subtracted from all
other data points in order to bring the minimum to zero.
Combination of CD an...
... classical secretory proteins
into the endoplasmic reticulum, import of proteins into
mitochondria and peroxisomes, as well as protein import
into and export from the nucleus), are understood in great
detail. ... FGF-1 homodimer in the cyto-
plasm. These are a cleavage product of the transmembrane
protein synaptotagmin consisting of its cytoplasmic domain
(p40-Syt1) and the...
... demonstrate that saratin interferes with inte-
grin a
2
b
1
binding to collagen in addition to inhibiting von Willebrand
factor–collagen binding, presumably by binding to an overlapping epitope
on collagen. ... demonstrates that saratin interferes with integrin
a
2
b
1
binding to collagen, in addition to inhibiting
VWF–collagen binding, presumably by binding to an
overlapp...