... cytoplasm. This induc-
ible nuclear–cytoplasmic translocation of FADD is independent of CD95
internalization, formation of the death- inducing signaling complex, and
caspase-8 activation. In contrast ... differential pathways directing FADD nuclear export and
cytoplasmic trafficking, and identify subcellular compartmentalization of
FADD as a novel regulatory mechanis...
... Haas M, Shapiro JI, Askari A & Xie Z
(2000) Ouabain interaction with cardiac Na+ ⁄ K+-
ATPase initiates signal cascades independent of changes
in intracellular Na+ and Ca2+ concentrations. ... enters the food chain
and accumulates mainly in fishes such as sardines,
herrings and anchovies from tropical seas, causing
neurological and gastrointestinal disturbances asso-
ciated with...
... this strain
and the ability of a cell harboring an individual library member to form a colony on minimal agar media lacking added phenylalanine and tyrosine
reports on the chorismate mutase activity ... dehydrogenase protein com-
plexes were replaced by genes encoding monofunctional
versions of the dehydratase and the dehydrogenase. The
growth of this strain on minimal media lacking...
... can induce
the activation of intracellular cascades such as the
mitogen-activated protein (MAP) kinase – also called
extracellular signal-regulated kinase (ERK) – cascade.
The serine ⁄ threonine ... as
substrate in PCR with the following Ras-GRF1 gene-speci-
fic primers: ON357, 5¢-TGAAACATCACCAACTAAATC
TCCAA-3¢; ON358, 5¢-GACGACTCCATTGTTATAGG
AAAAGAGT-3¢; ON359, 5 ¢-GCCGCTGGAGAAACAG
CA...
... transmembrane domain and the
serine ⁄ threonine kinase domain.
A. Herpin et al. BMP/activin pathway in Crassostrea gigas
FEBS Journal 272 (2005) 3424–3440 ª 2005 FEBS 3427
Daf-1 C. elegans
Crassostrea ... protostomal clade, the lophotrochozoa.
An increasing amount of comparative data from
ecdysozoans as well as from vertebrates suggests
that many of the proteins involved in mesod...
... physical
work environment variables. The Cochran-Armitage
trend test was performed in order to test if a gradual
increase in sickness absence was associated with in-
crease in risk of disability ... stronger among men (OR=3.13) than
among women (OR=2.19) (Table 2).
Additional analysis treating days of sickness ab-
sence during 1990 as a continuous variable showed a
c...
... (ATIS)
spoken language corpus. Preliminary
experiments yield 96% test set parsing
accuracy.
1 Motivation
As soon as a formal grammar characterizes a non-
trivial part of a natural language, ... Using an Annotated Corpus as a Stochastic Grammar
Rens Bod
Department of Computational Linguistics
University of Amsterdam
Spuistraat 134
NL-1012 VB Amsterdam
rens@alf.le...
... N-terminal,
regulatory and C-terminal, catalytic subdomains. The
regulatory domain contains a dimerization site, an
auto-inhibitory motif and several autophosphorylation
sites that have an effect on basal kinase activity, ... lnð
F
u
F
N
Þ¼DG
D
ð2Þ
By using an extrapolation method [43], the DG
H
2
O
D
-values
(conformational stability in absence of denaturant) was
then calculated.
[
3
H...
... was originally described as a PTK c-Abl SH3
domain-binding protein [25]. It contains an N-terminal
PH domain, a central proline-rich region that interacts
with c-Abl, and a C-terminal SH2 domain. ... and ZAP70 proteins of the Syk family of
tyrosine kinases. In addition, 3BP2 plays a positive
adapter function on basal and TCR-mediated NFAT
and AP-1 transcriptional activation i...
... not
necessarily allow us to heal underlying disease processes [2].
An unintended side effect of modern technological advances
has been the plausibility of maintaining moribund patients in a
state of ... to interject physician
paternalism into the surrogate decision-making equation is
ethically unacceptable. Most rational surrogates are unwilling
to continue life support after a re...