Báo cáo khoa học: Subcellular compartmentalization of FADD as a new level of regulation in death receptor signaling pdf

Báo cáo khoa học: Subcellular compartmentalization of FADD as a new level of regulation in death receptor signaling pdf

Báo cáo khoa học: Subcellular compartmentalization of FADD as a new level of regulation in death receptor signaling pdf

... cytoplasm. This induc- ible nuclear–cytoplasmic translocation of FADD is independent of CD95 internalization, formation of the death- inducing signaling complex, and caspase-8 activation. In contrast ... differential pathways directing FADD nuclear export and cytoplasmic trafficking, and identify subcellular compartmentalization of FADD as a novel regulatory mechanis...
Ngày tải lên : 07/03/2014, 02:20
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Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: a new view of palytoxin toxicity ppt

Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: a new view of palytoxin toxicity ppt

... Haas M, Shapiro JI, Askari A & Xie Z (2000) Ouabain interaction with cardiac Na+ ⁄ K+- ATPase initiates signal cascades independent of changes in intracellular Na+ and Ca2+ concentrations. ... enters the food chain and accumulates mainly in fishes such as sardines, herrings and anchovies from tropical seas, causing neurological and gastrointestinal disturbances asso- ciated with...
Ngày tải lên : 18/02/2014, 14:20
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Tài liệu Báo cáo khoa học: Deciphering enzymes Genetic selection as a probe of structure and mechanism docx

Tài liệu Báo cáo khoa học: Deciphering enzymes Genetic selection as a probe of structure and mechanism docx

... this strain and the ability of a cell harboring an individual library member to form a colony on minimal agar media lacking added phenylalanine and tyrosine reports on the chorismate mutase activity ... dehydrogenase protein com- plexes were replaced by genes encoding monofunctional versions of the dehydratase and the dehydrogenase. The growth of this strain on minimal media lacking...
Ngày tải lên : 19/02/2014, 12:20
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Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

... can induce the activation of intracellular cascades such as the mitogen-activated protein (MAP) kinase – also called extracellular signal-regulated kinase (ERK) – cascade. The serine ⁄ threonine ... as substrate in PCR with the following Ras-GRF1 gene-speci- fic primers: ON357, 5¢-TGAAACATCACCAACTAAATC TCCAA-3¢; ON358, 5¢-GACGACTCCATTGTTATAGG AAAAGAGT-3¢; ON359, 5 ¢-GCCGCTGGAGAAACAG CA...
Ngày tải lên : 19/02/2014, 18:20
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Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

... transmembrane domain and the serine ⁄ threonine kinase domain. A. Herpin et al. BMP/activin pathway in Crassostrea gigas FEBS Journal 272 (2005) 3424–3440 ª 2005 FEBS 3427 Daf-1 C. elegans Crassostrea ... protostomal clade, the lophotrochozoa. An increasing amount of comparative data from ecdysozoans as well as from vertebrates suggests that many of the proteins involved in mesod...
Ngày tải lên : 07/03/2014, 21:20
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Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"

Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"

... physical work environment variables. The Cochran-Armitage trend test was performed in order to test if a gradual increase in sickness absence was associated with in- crease in risk of disability ... stronger among men (OR=3.13) than among women (OR=2.19) (Table 2). Additional analysis treating days of sickness ab- sence during 1990 as a continuous variable showed a c...
Ngày tải lên : 26/10/2012, 10:03
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Tài liệu Báo cáo khoa học: "Using an Annotated Corpus as a Stochastic Grammar" ppt

Tài liệu Báo cáo khoa học: "Using an Annotated Corpus as a Stochastic Grammar" ppt

... (ATIS) spoken language corpus. Preliminary experiments yield 96% test set parsing accuracy. 1 Motivation As soon as a formal grammar characterizes a non- trivial part of a natural language, ... Using an Annotated Corpus as a Stochastic Grammar Rens Bod Department of Computational Linguistics University of Amsterdam Spuistraat 134 NL-1012 VB Amsterdam rens@alf.le...
Ngày tải lên : 22/02/2014, 10:20
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Báo cáo khoa học: The hinge region operates as a stability switch in cGMP-dependent protein kinase Ia doc

Báo cáo khoa học: The hinge region operates as a stability switch in cGMP-dependent protein kinase Ia doc

... N-terminal, regulatory and C-terminal, catalytic subdomains. The regulatory domain contains a dimerization site, an auto-inhibitory motif and several autophosphorylation sites that have an effect on basal kinase activity, ... lnð F u F N Þ¼DG D ð2Þ By using an extrapolation method [43], the DG H 2 O D -values (conformational stability in absence of denaturant) was then calculated. [ 3 H...
Ngày tải lên : 07/03/2014, 09:20
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Báo cáo khoa học: SHP-1 dephosphorylates 3BP2 and potentially downregulates 3BP2-mediated T cell antigen receptor signaling ppt

Báo cáo khoa học: SHP-1 dephosphorylates 3BP2 and potentially downregulates 3BP2-mediated T cell antigen receptor signaling ppt

... was originally described as a PTK c-Abl SH3 domain-binding protein [25]. It contains an N-terminal PH domain, a central proline-rich region that interacts with c-Abl, and a C-terminal SH2 domain. ... and ZAP70 proteins of the Syk family of tyrosine kinases. In addition, 3BP2 plays a positive adapter function on basal and TCR-mediated NFAT and AP-1 transcriptional activation i...
Ngày tải lên : 07/03/2014, 12:20
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Báo cáo khoa học: "Medical treatment for the terminally ill: the ‘risk of unacceptable badness’"

Báo cáo khoa học: "Medical treatment for the terminally ill: the ‘risk of unacceptable badness’"

... not necessarily allow us to heal underlying disease processes [2]. An unintended side effect of modern technological advances has been the plausibility of maintaining moribund patients in a state of ... to interject physician paternalism into the surrogate decision-making equation is ethically unacceptable. Most rational surrogates are unwilling to continue life support after a re...
Ngày tải lên : 25/10/2012, 10:45
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