Báo cáo khoa học: cAMP response element-binding protein (CREB) is imported into mitochondria and promotes protein synthesis docx

Báo cáo khoa học: cAMP response element-binding protein (CREB) is imported into mitochondria and promotes protein synthesis docx

Báo cáo khoa học: cAMP response element-binding protein (CREB) is imported into mitochondria and promotes protein synthesis docx

... cAMP response element-binding protein (CREB) is imported into mitochondria and promotes protein synthesis Domenico De Rasmo 1 , Anna Signorile 1 , Emilio Roca 1 and Sergio Papa 1,2 1 ... of CREB, cAMP and cPKA on mitochondrial protein synthesis. Mitochondrial protein synthesis was performed in a rat liver mitochondria suspension in the presence of [...
Ngày tải lên : 07/03/2014, 02:20
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Tài liệu Báo cáo khoa học: 1,5-Diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases ppt

Tài liệu Báo cáo khoa học: 1,5-Diamino-2-pentyne is both a substrate and inactivator of plant copper amine oxidases ppt

... dehydrogenation and is hard to reconcile with a particular structure. It should be pointed out that only the peaks with m/z 135.1 and 132.1 are consistent with only the N 1 - and not the N 5 -isomer, and ... French]. 16. Qiao, C. (2004) New copper amino oxidase probes: synthesis, mechanism and enzymolo gy. PhD Thesis, Case Western Reserve University, Cleveland, OH. 17. Torchy, S...
Ngày tải lên : 19/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo⁄maltodextrin-binding protein ppt

Tài liệu Báo cáo khoa học: Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo⁄maltodextrin-binding protein ppt

... but the distance between Od2 of Asp209 and Ng2 of Arg344 is only 10.2 A ˚ .InTliTMBP, the cleft is the smallest among the three proteins (Fig. 7C). The ligand, trehalose, is half-buried, and the ... sugar-binding protein family was found to be located upstream of the TVA II gene, and the affinities of this protein for c-CD were higher than that for maltose [7]. The results sugg...
Ngày tải lên : 19/02/2014, 00:20
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Tài liệu Báo cáo khoa học: Impact of the native-state stability of human lysozyme variants on protein secretion by Pichia pastoris doc

Tài liệu Báo cáo khoa học: Impact of the native-state stability of human lysozyme variants on protein secretion by Pichia pastoris doc

... appear to cause amyloidosis, but Keywords amyloidosis; lysozyme; protein degradation; protein folding; protein secretion Correspondence C. M. Dobson, Department of Chemistry, Lensfield Road, University ... expression of the recently discovered F57I and W64R lysozyme variants from P. pastoris resulted in yields of 0.04 and 0.3 mgÆL )1 , respectively, based on UV–visible (UV-vis) spect...
Ngày tải lên : 19/02/2014, 08:20
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Báo cáo khoa học: Interaction of the general transcription factor TnrA with the PII-like protein GlnK and glutamine synthetase in Bacillus subtilis potx

Báo cáo khoa học: Interaction of the general transcription factor TnrA with the PII-like protein GlnK and glutamine synthetase in Bacillus subtilis potx

... binding affinity of this site is in the milli- molar range, which is considered to be physiologically relevant, and that this signal is then transmitted to TnrA. BIAcore analysis of the GS–TnrA interaction The ... nitrogen- limited conditions [13]. GlnK consists of three 12-kDa monomers, and is a small regulatory protein that belongs to the PII protein family. GlnK homologs bin...
Ngày tải lên : 06/03/2014, 00:21
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Báo cáo khoa học: Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx

Báo cáo khoa học: Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx

... and II (IGF-I and -II) and their affinity for these ligands is modulated by several mechanisms: attachment to the extracellular matrix and post-translational modifica- tions, such as proteolysis, ... during gestation and, as a modula- tor of insulin-like growth factors or by independent mechanisms, regulates embryonic implantation and growth. The protein is phosphorylated and...
Ngày tải lên : 07/03/2014, 00:20
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Báo cáo khoa học: The hinge region operates as a stability switch in cGMP-dependent protein kinase Ia doc

Báo cáo khoa học: The hinge region operates as a stability switch in cGMP-dependent protein kinase Ia doc

... Sigma, Zwijndrecht, the Netherlands) in 50% of mixture B into the ESI-TOF-MS after the gradient had finished. Acknowledgements Martijn Pinkse, Akira Honda, Sander Engels and Christian Nickl are kindly ... 272, 10522–10528. 14 Reed RB, Sandberg M, Jahnsen T, Lohmann SM, Francis SH & Corbin JD (1996) Fast and slow cyclic nucleotide-dissociation sites in cAMP- dependent protein kinas...
Ngày tải lên : 07/03/2014, 09:20
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Báo cáo khoa học: " Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit"

Báo cáo khoa học: " Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit"

... established on this drug was admitted to the ICU. Although we did not prospec- tively look for all missed prescriptions, standard care was for the pharmacist to review admissions and note discrepancies between ... and this may have affected the results. Ideally, the impact of this could be minimised by sampling over a longer period and more frequently, but this was beyond the scope and...
Ngày tải lên : 25/10/2012, 10:39
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Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

... with increased risk of cardiovascular disease, the leading cause of death. Therefore, it is important to understand the molecular basis underly- ing obesity and related metabolic diseases in order ... signal sequence in the N-terminus and ANGPTL6 ⁄ AGF protein is detected in the circulation, indicating that it is secreted [9,13]. ANGPTL6 ⁄ AGF induces angio- genesis and arteriog...
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx

... SR (serine- and arginine-rich proteins) family of splicing factors. CAPER, a SR-like protein, interacts with ERa and the progesterone receptor and modulates the ligand-dependent transcription and alternate ... regulation and mixed lineage leukemia. Acknowledgements We thank Imran Hussain, Sahba Kasiri, Bishakha Shrestha, Saoni Mandal and other Mandal lab mem- bers for useful disc...
Ngày tải lên : 16/02/2014, 14:20
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