... impairs DNA repair rate in chromatin
FEBS Journal 276 (2009) 6646–6657 ª 2009 The Authors Journal compilation ª 2009 FEBS 6657
The nucleosome-binding protein HMGN2 modulates global
genome repair
Mangalam ... decrease in the CPD content
of the DNA of all the cells, an indication of active
repair of the damaged DNA. However, the removal of
CPDs from the chromat...
... mixing together HIS-OXI1 and GST-PTI1-4
proteins or HIS-PTI1-4 and GST-OXI1 proteins, the
GST-tagged proteins were pulled down with glutathi-
one-agarose beads. The proteins were then detected ... pathogen attack.
The Arabidopsis genome encodes 39 AGC kinases,
of which 23 are classified to the AGC VIII group [8,9].
The AGC kinases were named on the basis of their
homology to the...
... independent
proteins and peptides leads to the disassembly of the
spherical capsid inside the virion. Some of the folded
domains of Gag are then able to reassemble as inde-
pendent proteins. The matrix protein ... involved either in the assembly of the immature
HIV-1 capsid, or in the reassembly of CA into a
mature capsid. The detailed description of the structure
and co...
... polyprotein, yields the matrix protein (MA),
the capsid protein (CA), the nucleocapsid protein
(NC) and p6 proteins, as well as two spacer pep-
tides.
Currently, most of the available drugs in the ... folding of both the CAI peptide and a-helix 9
of CTD during formation of the peptide–
protein and protein protein complexes.
These NMR experiments also allowed the dete...
... [10].
The curve fits to the data points for tadpole narcosis
by the additional alcohols of Table 1 are shown in
Fig. 2 along with the theoretical curves for the
enhancement of agonist binding to the ... constant. The curves for the
nAChR shown on the right were calculated
as described in the Results. The following
fitted curves to the data points (d)for
tadpole narcosis...
... anti-T7) was then used to monitor the location of the
epitope-tagged region with respect to the KdpD protein in
the membrane. The KdpD protein with the epitope tags was
readily digested by proteinase ... and was not digested by the
protease. Taken together, these results suggest that the
second periplasmic loop of the wild-type KdpD protein is
inserted into the membr...
... humans. The RNA genome of
the virus encodes a Gag polyprotein, which is further processed into
matrix, capsid and nucleocapsid proteins. These proteins play a significant
role at several steps in the ... 6118–6127 ª 2009 The Authors Journal compilation ª 2009 FEBS
contains the viral RNA genome coated by the NC
protein. The mature virion can then infect other host
cells. Alon...
... demonstrating: (a) the inability
of the mutant to insert a cofactor, and (b) the specific
origin of the signal in the other samples. The cytosolic
fraction of the complemented wild-type clearly showed
the EPR ... between
the total activity in the nonfractionated cell lysate and
the sum of the individual fractions can be easily
explained by either loss of material or pr...
... example
and then used to generate a prediction for the left-
out example. The meta-classifier is trained using the
predictions of the base-level classifiers as features,
and the true label as given by the ... Under these re-
strictions, RE became an instance of entity labeling,
where the label assigned to an entity (e.g. Father) is
its relation to the topic of the article.
Oth...
... brain. The solubilization of the ICD of
RNF13 and the presence of the putative NLS on the
C-terminal side of the TM domain are consistent with
the possibility that the ICD, released from the mem-
brane ... suggesting
that the N-terminal portion of the protein containing
the HA epitope was lost from these proteins by pro-
teolysis.
To determine which of the RNF13 ba...