Báo cáo khoa học: Sirt1 and mir-9 expression is regulated du

Báo cáo khoa học: Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic b-islets ppt

... whether Sirt1 itself was regulated in b-islets during insulin secretion. Our results show, for the ﬁrst time, that Sirt1 expression is altered in insulin- secreting b-islets during GSIS in vivo. Using ... that the amount of Sirt1 protein is regulated (post-transcrip- tionally) during GSIS in insulin- secreting b-islets in vivo. Sirt1 is down -reg...

Ngày tải lên : 06/03/2014, 00:21

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Tài liệu Báo cáo khoa học: Characterization and functional expression of cDNAs encoding thyrotropin-releasing hormone receptor from Xenopus laevis Identiﬁcation of a novel subtype of thyrotropin-releasing hormone receptor ppt

... been cloned and characterized from rats [30,31], mice [32] and ﬁsh [28]. Rat TRHR2 is more widely distributed in the brain than is TRHR1 [33] and they differ in their agonist-induced internalization and ... expressing xTRHR2 and xTRHR1 cDNAs. Distribution of xTRHRs. The distributions of xTRHRs in the brain, liver, testis, urinary bladder, stomach, ventral and dorsal skin...

Ngày tải lên : 21/02/2014, 03:20

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Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx

... including investigations in human tissues, and that this has implications for how to interpret the role of the stud- ied enzymes in health and disease. Results The distribution and relative intensity ... rectum in mice, whereas corresponding rat tissues show expression only in duodenum, colon and rectum. In both mouse and rat, Adh4 is found in the epithelial lining...

Ngày tải lên : 16/03/2014, 11:20

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Báo cáo khoa học: Neuroglobin and cytoglobin expression in mice Evidence for a correlation with reactive oxygen species scavenging doc

... cytoglobin (Cygb) are two new members of the globin family. Ngb is mainly expressed in the cytoplasm of neuronal (brain and retina) and some endocrine tissues, whereas Cygb is detected in the ... neuroglobin and cytoglobin in a situation of chronic hypoxia in mice were examined using real-time quantitative PCR. The kinetics of the hypoxic expression of neuroglobin (brain,...

Ngày tải lên : 23/03/2014, 09:21

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Tài liệu Báo cáo khoa học: Molecular and cellular speciﬁcity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx

... decapeptides. In addition to the antisera r-anti-l (made in rat) and gp-anti-dW4 (produced in guinea pig), two antisera discriminating CHH isomers (gp-anti-pQl made in guinea pig and rb-anti- pQd in rabbit) ... Universite ´ Paris, France Introduction Modiﬁcation of the chirality of a single aminoacyl resi- due within a peptide chain is a subtle and intriguing mechanism that...

Ngày tải lên : 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Structural and biochemical characterization of a human adenovirus 2/12 penton base chimera pptx

... base binding to integrin. The process by which integrin binding may be coupled to structural changes in the penton base, allowing fiber release, is not clear, but could involve changes in the ... fiber binding or fiber release was coupled to changes in the hypervariable loop. Binding assays Owing to difficulties in expressing and purifying the full-length fiber protein, a 75 amino acid...

Ngày tải lên : 19/02/2014, 06:20

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Tài liệu Báo cáo khoa học: Cloning and characterization of CBL-CIPK signalling components from a legume (Pisum sativum) ppt

... proteins contain four Ca 2+ -binding EF hand motifs [9] and functions by interacting and regulating a group of Ser ⁄ Thr protein kinases called CBL-interacting protein kinases Keywords abscisic ... (SD) lacking Leu, Trp, and His (SD-Leu – Trp – His – and containing 15 mm 3-aminotrizole, 3-AT). 3-AT is a competitive inhibitor of histidine and checks any leaky expression of hist...

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khoa học: Diego and friends play again Old planar cell polarity players in new positions doc

... almost cer- tainly relevant to this issue is that the same Ft ⁄ Ds ⁄ Fj module is involved in the proximal-distal patterning of the wing and leg [12,45–48], and hence it is tempting to speculate ... polarity establishment (at least in the wing) is directly coupled to growth and patterning of the tissue (see also [23]). Direct evidence in support of this view is missing...

Ngày tải lên : 20/02/2014, 01:20

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Báo cáo khoa học: Structural and functional aspects of unique type IV secretory components in the Helicobacter pylori cag-pathogenicity island potx

... ﬁndings may indicate that CagD is released into the supernatant during host cell infec- tion by an unknown independent mechanism and then binds to the host cell surface or is incorporated in ... molecule involving a-helix A, the nearby loop, the ﬁrst and last turns of helices E and F, and the C-terminus helices I and J. In addition, there is a lysine-rich N- and C-ter-...

Ngày tải lên : 06/03/2014, 00:21

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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx

... pK a calculations and available structural informa- tion. The results indicate that the pK a of the catalytic acid (Glu144) is ÔcycledÕ during catalysis as a consequence of substrate-binding and release and, ... pK a ,muta- genesis, pH optimum. Chitin, a b-1,4-linked polymer of N-acetylglucosamine (GlcNAc), is degraded in nature by chitinases and b-N- 1-4-acetylhexosaminidases...

Ngày tải lên : 07/03/2014, 14:20

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