Tài liệu Báo cáo khoa học: The solution structure of reduced dimeric copper zinc superoxide dismutase doc

Tài liệu Báo cáo khoa học: The solution structure of reduced dimeric copper zinc superoxide dismutase doc

Tài liệu Báo cáo khoa học: The solution structure of reduced dimeric copper zinc superoxide dismutase doc

... solve the solution structure of the reduced dimeric protein (by using a classical NMR approach) in order to compare the solution structures of the monomeric and dimeric species as well as the solution ... dimeric Cu,Zn SOD (Eur. J. Biochem. 269) 1915 The solution structure of reduced dimeric copper zinc superoxide dismutase The structural ef...
Ngày tải lên : 21/02/2014, 03:20
  • 11
  • 575
  • 0
Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

... present for the last four residues at the C-terminus. The stereochemistry of the model has been assessed using the program procheck [23]. Ninety per cent of the residues fall in the most favoured regions ... mol- ecules. When the R-factor decreased to a value of 0.27 at 2.0 A ˚ resolution, inspection of the electron density map in the enzyme active site clearly rev...
Ngày tải lên : 18/02/2014, 06:20
  • 9
  • 796
  • 0
Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

... A ˚ resolution by the molecular replacement method. The schematic view of the overall structure is shown in Fig. 3A. Theenzymeexistsasadimeroftheabc heterotrimer. There is a noncrystallographic twofold ... twofold axis around the center of Fig. 3A. The structure of an abc heterotrimer unit is shown in Fig. 3B. The central region of the a subunit constitutes the (b/...
Ngày tải lên : 21/02/2014, 03:20
  • 11
  • 602
  • 0
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the DNA. Conservation of spacing is required for optimal pro- moter activity because changing the ... However, as in most other CDE ⁄ CHR promoters, mutation of the CHR results in a smaller remaining cell cycle-regulation than alteration of the CDE [37]. Interestingly,...
Ngày tải lên : 16/02/2014, 09:20
  • 17
  • 876
  • 0
Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc

... involved either in the assembly of the immature HIV-1 capsid, or in the reassembly of CA into a mature capsid. The detailed description of the structure and conformational dynamics of these interfaces, together ... helix 4 of the NTD of a neighboring subunit in the hexamer. Additional contacts involve helix 11 of the CTD and the C-terminal end of helix 7 o...
Ngày tải lên : 18/02/2014, 06:20
  • 12
  • 577
  • 0
Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly ppt

Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly ppt

... at Thr188. The two addi- tional aromatic residues in each monomer, Tyr164 and Fig. 1. Structure of the CTD dimer. X-ray structure of CTD showing the dimeric structure of the domain. The monomers ... the X-ray structure of the nonmu- tated-CTD–CAI complex [28] (Fig. 2A, main panel). The aromatic moiety of Phe3, together with Leu6 and Ile1, are the residues...
Ngày tải lên : 18/02/2014, 06:20
  • 8
  • 593
  • 0
Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

... Furthermore, the pro-peptide of GDF-8 impairs interaction of the mature part with its receptors [16]. In the case of BMP-9, the pro-pep- tide appears not to alter significantly the activity of the mature ... here suggest that the pro-domain of BMP-2 can alter the signalling properties of the growth factor by modulating the ability of the mature part to inter...
Ngày tải lên : 18/02/2014, 06:20
  • 13
  • 892
  • 0
Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc

... into the chitinolytic poten- tial of L. lactis, the present results provide only the third example of the role of family 33 CBPs in the deg- radation of recalcitrant polysaccharides. Furthermore, the ... [10]. Although the occurrence of family 33 CBPs has been known for some time [23], the present results provide only the third demonstration of the accessory fu...
Ngày tải lên : 18/02/2014, 08:20
  • 14
  • 683
  • 0
Tài liệu Báo cáo khoa học: The intracellular region of the Notch ligand Jagged-1 gains partial structure upon binding to synthetic membranes docx

Tài liệu Báo cáo khoa học: The intracellular region of the Notch ligand Jagged-1 gains partial structure upon binding to synthetic membranes docx

... e.g. the case of the association between the N-terminal region of the membrane-bound tyrosine kinase Lck with the cytoplasmic tail of the T-cell coreceptors CD4 or CD8 [37]. In solution, on the ... dispersion of 0.16 p.p.m. (supplementary Figure S1). The lack of chemical shift dispersion in the HN region as well as in the methyl region (data not shown) is an ind...
Ngày tải lên : 18/02/2014, 16:20
  • 12
  • 502
  • 0
Tài liệu Báo cáo khoa học: The conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein Characterization of cold denaturation and urea–protein interactions doc

Tài liệu Báo cáo khoa học: The conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein Characterization of cold denaturation and urea–protein interactions doc

... (enzyme I of the PTS), the first protein in the cascade of proteins forming the PTS, to HPr, the histidine-phosphocarrier protein. HPr is the smallest protein in the protein cascade of the PTS and ... from the fitting of the CD thermal denaturation data to Eqn (1). Fitting of the thermal and urea-denaturation data (using the approach of Pace and Laurents [39]...
Ngày tải lên : 19/02/2014, 12:20
  • 17
  • 612
  • 0

Xem thêm

Từ khóa: