Tài liệu Báo cáo khoa học: Evidence for proteasome dysfunction in cytotoxicity mediated by anti-Ras intracellular antibodies pdf

Tài liệu Báo cáo khoa học: Evidence for proteasome dysfunction in cytotoxicity mediated by anti-Ras intracellular antibodies pdf

Tài liệu Báo cáo khoa học: Evidence for proteasome dysfunction in cytotoxicity mediated by anti-Ras intracellular antibodies pdf

... Evidence for proteasome dysfunction in cytotoxicity mediated by anti-Ras intracellular antibodies Alessio Cardinale, Ilaria Filesi, Sonia Mattei and Silvia ... Italy Anti-Ras intracellular antibodies inhibit cell proliferation in vivo by sequestering the antigen and diverting it from its physiological location [Lener, M., Horn, I. R., Cardinale, A., Messina, .....
Ngày tải lên : 21/02/2014, 00:20
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Tài liệu Báo cáo khoa học: Evidence for noncooperative metal binding to the a domain of human metallothionein ppt

Tài liệu Báo cáo khoa học: Evidence for noncooperative metal binding to the a domain of human metallothionein ppt

... tetra- thiolate sites, the choice for the third incoming metal ion would be to form a bridging interaction in the a domain or to form another independent tetrathiolate site in the b domain. It is probable that ... to coordinate to the two-domain ba-MT in a domain-specific manner, with a preference for the a domain, has been construed as being an indicator of cooperative metal binding...
Ngày tải lên : 19/02/2014, 00:20
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Tài liệu Báo cáo khoa học: Evidence for interactions between domains of TatA and TatB from mutagenesis of the TatABC subunits of the twin-arginine translocase docx

Tài liệu Báo cáo khoa học: Evidence for interactions between domains of TatA and TatB from mutagenesis of the TatABC subunits of the twin-arginine translocase docx

... an essential twin-arginine motif in the N-terminal domain [9,10]. They then interact with a translocon in the inner membrane that consists, minimally, of three sub- units (TatABC) in Escherichia ... specificity determinant for protein secretion via the twin-arginine translocation pathway. J Biol Chem 275, 41350–41357. 16 Pop O, Martin U, Abel C & Muller JP (2002) The twin- arginine...
Ngày tải lên : 19/02/2014, 17:20
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Tài liệu Báo cáo khoa học: Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells docx

Tài liệu Báo cáo khoa học: Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells docx

... changes in the cytoskeleton that may occur during the initial 6 h window of infection. We infected RPE cells with K26GFP [27], and stained cells for F-actin, using phalloidin at 30 min and 6 h postinfection, ... FEBS 5281 damine-conjugated phalloidin (Invitrogen) was added for F-actin staining at room temperature for 45 min. Finally, the cells were washed three times with 1· NaCl ⁄ P...
Ngày tải lên : 18/02/2014, 14:20
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

... Diego, CA, USA) binding and PI staining were performed according to [44]. Following incubation with 1.0 lgÆmL )1 annexin V and 4.0 lgÆmL )1 PI for 20 min, cells were analyzed by flow cytometry. Preparation ... detected by Nile red stain- ing as previously described [42]. Cell imaging for Nile red staining was performed by confocal microscopy. Quantifica- tion of lipid droplets was per...
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf

Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf

... protein 1 ⁄ core pro- tein 2) in a large core structure that also includes the chaperone protein Bcs1p. This core structure is then able to sequentially bind the remaining bc 1 subunits in a ... [45] and the transformants were then selected for leucine prototrophy. The double deletion strains were constructed by crossing selected single deletion strains. The resulting diploids were sp...
Ngày tải lên : 18/02/2014, 08:20
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Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt

Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt

... European Bioinformatics Institute’s server (http://www.ebi.ac.uk/) for clu- stalw2 [53] as Phylip-tree type and neighbour-joining clustering [26] using the alignment of complete sequences, including ... cDNA involved in cystine, dibasic, and neutral amino acid transport. J Clin Invest 91, 1959–1963. 26 Saitou N & Nei M (1987) The neighbor-joining method: a new method for reconstruct...
Ngày tải lên : 18/02/2014, 13:20
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Tài liệu Báo cáo khoa học: Progress for dengue virus diseases Towards the NS2B–NS3pro inhibition for a therapeutic-based approach ppt

Tài liệu Báo cáo khoa học: Progress for dengue virus diseases Towards the NS2B–NS3pro inhibition for a therapeutic-based approach ppt

... A synergistic increase in neutralizing antibody titers by Table 1. Vaccines against dengue fever by the Initiative for Vaccine Research, World Health Organization, updated February 2006. Type of vaccine Pharmaceutical company ... also for the correct interaction with the substrate. The binding site of the NS2B cofac- tor could be examined for a view to inhibitor develop- ment, and...
Ngày tải lên : 19/02/2014, 00:20
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Tài liệu Báo cáo khoa học: Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina doc

Tài liệu Báo cáo khoa học: Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina doc

... N-ter- minal or C-terminal histidine tags. For that purpose, a cod- ing sequence for six histidines was introduced by PCR either at the N-terminus, after the ATG, or at the C-termi- nus before the ... protein had a similar activity in crude yeast extract as the untagged protein, indicating that the tag was not interfering with the protein activity. The tagged protein was purified and t...
Ngày tải lên : 19/02/2014, 06:20
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Tài liệu Báo cáo khoa học: "Sentence-For-Sentence Translation: An Example" ppt

Tài liệu Báo cáo khoa học: "Sentence-For-Sentence Translation: An Example" ppt

... outlined in Figure 1. Each Arabic letter has several forms. The particular form selected in any given instance is determined by the preceding and following letters. In general, there- fore, in ... input sentence remains intact, in order and form, as it does in the present program. The only changes which are made are in the form of added elements making grammatical inform...
Ngày tải lên : 19/02/2014, 19:20
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