Tài liệu Báo cáo khoa học: Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity docx

Tài liệu Báo cáo khoa học: Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity docx

Tài liệu Báo cáo khoa học: Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity docx

... of the hairpin loop in mussel defensin activity (Eur. J. Biochem. 270) 2811 From our observations, it is not possible to infer whether the key role of the b-hairpin loop of MGD1 (loop 3) in antimicrobial ... Ôresidues in the protruding domain consisting of the type VI b-turn and the first part of b-strand 3Õ (i.e. the b-hairpin loop and part of...
Ngày tải lên : 20/02/2014, 11:20
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx

Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx

... obtained indicate that the KIND2 domain is necessary and sufficient for the targeting of v-KIND to dendrites of neurons. To investigate the MAP2-binding characteristics of the KIND domain protein ... in the central domain of MAP2 contain the v-KIND binding core module MAP2 consists of three main structural domains: the cAMP-dependent protein kinase regulatory subunit...
Ngày tải lên : 14/02/2014, 19:20
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Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt

Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt

... obese mice In order to gain insights into the potential biologically relevant role of miR-27 in the regulation of adipose tis- sue functions in vivo, we examined the expression of miR-27 in the genetically ... together, these results illustrate a critical and specific role of miR-27 in the regulation of adipogenic differentiation. miR-27 prevents the inducti...
Ngày tải lên : 18/02/2014, 08:20
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Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx

Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx

... and the intersubunit disulfides that link the two subunits of BS-RNase. Monomeric derivatives of the protein are inactive as cytotoxic agents when they are prepared by reductive cleavage of the intersubunit ... for its display of cytotoxic activity [3]. This conclusion was based on the lack of cytotoxic activity in a monomeric derivative of the protein obtaine...
Ngày tải lên : 20/02/2014, 11:20
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Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf

Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf

... that the Trp169– His210 pair functions in the high catalytic activity of this protease at pH9 [10]. Further interest in the aromatic stacking is in the role of the electrostatic properties in enzymatic ... solvent. The aromatic stacking regulates the low activity at neutral pH and the high activity at alkaline pH due to the interference of the hydroge...
Ngày tải lên : 21/02/2014, 03:20
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Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

... disambiguated word meaning. It is the in interaction of the results of these asynchronous processes that the process of comprehension is defined. The processes are independent of the know- ledge ... affected. The study includes off-line picture naming which forces use of articles in all of the above contexts, as well as on-line production of these morph...
Ngày tải lên : 21/02/2014, 20:20
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Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt

Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt

... near the N- and C-termini of the linkers: this suggests that a mobile connection with both the catalytic domain and the binding module is required for the function of the nanomachine. Furthermore, ... C-terminal domain. URLs of the relevant genome databases are given in Table S1. The linker between the core enzyme and its C-terminal domain was defined as the regio...
Ngày tải lên : 14/02/2014, 18:20
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Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf

Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf

... Yer- sinia, the increased synthesis of LcrV triggered by the activation of the system leads to the titration of LcrG, which binds LcrV in a 1 : 1 complex. In turn, this results in a release of the ... by the sug- gestion that pH sensing by Salmonella involves modi- fications in the assembly of the translocon, which affect the pH gradient within the needle,...
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Hsp105b upregulates hsp70 gene expression through signal transducer and activator of transcription-3 pdf

Tài liệu Báo cáo khoa học: Hsp105b upregulates hsp70 gene expression through signal transducer and activator of transcription-3 pdf

... resulting in the induction of Hsp70 expression. STAT3 is required for the induction of hsp70 promoter activity by Hsp105b To further demonstrate that STAT3 plays essential roles in the activation of ... HSF1, binds to the region between )206 and )187 bp of the hsp70 promoter Next, we investigated protein binding to the region between )206 and )187 bp of the hsp70...
Ngày tải lên : 18/02/2014, 06:20
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Tài liệu Báo cáo khoa học: Studies on structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis H37Rv pdf

Tài liệu Báo cáo khoa học: Studies on structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis H37Rv pdf

... WhiB proteins except WhiB2, the amino acid imme- diately after the C-terminal cysteine of the CXXC motif is proline (Fig. S6). In WhiB2 the absence of proline and therefore of the kink might ... out. Interestingly, in WhiB5 despite the insertion of an extra amino acid between the two cysteines of the CXXC motif, the protein retained disulfide reduc- tase acti...
Ngày tải lên : 18/02/2014, 12:20
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