Tài liệu Báo cáo khoa học: Proteasome involvement in the degradation of the Gq family of Ga subunits pptx

Tài liệu Báo cáo khoa học: Proteasome involvement in the degradation of the Gq family of Ga subunits pptx

Tài liệu Báo cáo khoa học: Proteasome involvement in the degradation of the Gq family of Ga subunits pptx

... al. Proteasome degradation of G q proteins Proteasome involvement in the degradation of the G q family of Ga subunits Bente B. Johansson, Laura Minsaas and Anna M. Aragay Department of Biomedicine, ... of Ga 16 and Ga q subunits. Therefore the lack of change in the rate of degradation cannot be due to lack of receptor-activa- tion of the...
Ngày tải lên : 20/02/2014, 03:20
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Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx

Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx

... domain, a transmembrane domain and an intracellular tyrosine kinase domain. The binding of a ligand to the extracel- lular domain of the EGFR induces receptor dimeriza- tion, activation of the intracellular ... result in the up-regulation of CDK inhib- itors, including KIP family members and INK4 family members Members of the KIP family can inhibit the catalyti...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor doc

Tài liệu Báo cáo khoa học: Brain angiogenesis in developmental and pathological processes: therapeutic aspects of vascular endothelial growth factor doc

... astrocytes, and the tight junctions of vascular endothelial cells (ECs) in the BBB are well organized with claudins and ZO- proteins through a decrease in angiogenesis signaling and an increase in the stability ... among tissues in the body, and the risk of edema to brain functions should be carefully considered. Brain edema may increase pressure in the cranial cavit...
Ngày tải lên : 18/02/2014, 11:20
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx

Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx

... [17–19]. Pantothenate kinase is an essential regulatory enzyme in co-enzyme A biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine and pantetheine ... destinations. Cells from NPC subjects show a decrease in acid sphingomyelinase activity, leading to the accumulation of sphingomyelin [27]. Because one of the pathways for c...
Ngày tải lên : 18/02/2014, 14:20
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Tài liệu Báo cáo khoa học: Fermentative lifestyle in yeasts belonging to the Saccharomyces complex ppt

Tài liệu Báo cáo khoa học: Fermentative lifestyle in yeasts belonging to the Saccharomyces complex ppt

... amino acid biosynthesis. Much of the generation of NADH during amino acid biosyn- thesis takes place in the mitochondria. Because of the block in the respiratory chain caused by the addition of ... N 2 (containing less than 3 p.p.m. O 2 ) at a flow rate of 0.1 LÆmin )1 per liter of medium, and a stir rate of 500 r.p.m. was maintained. In order to minimize the di...
Ngày tải lên : 19/02/2014, 02:20
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf

Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf

... using the main chain of residues Ser12 fiThr70 in t he structure a lignment. (B) O verlap of the X-ray structure with the 30 °C NMR structure using the main chain of residues Ser12fiThr70 in the ... effect: the binding of AFP causes the ice between the bound proteins to grow as a curved front, where further growth becomes energetically unfavourable [7]. In this pro...
Ngày tải lên : 19/02/2014, 16:20
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Tài liệu Báo cáo khoa học: "Word Order in German: A Formal Dependency Grammar Using a Topological Hierarchy" pptx

Tài liệu Báo cáo khoa học: "Word Order in German: A Formal Dependency Grammar Using a Topological Hierarchy" pptx

... it joins the right bracket. The other rules are identical to those for other domains, with the group containing the pronominal part of the relative pronoun having to join the other part of the ... in the complementizer field. In a sense, the complementizer field acts like the fusion of the Vorfeld and the left bracket of the main domain: The complementi...
Ngày tải lên : 20/02/2014, 18:20
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Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt

Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt

... near the N- and C-termini of the linkers: this suggests that a mobile connection with both the catalytic domain and the binding module is required for the function of the nanomachine. Furthermore, ... spring, allowing the nanomachine (catalytic domain–linker–binding module) to crawl on the substrate surface. The possible functional implications of the linker primary...
Ngày tải lên : 14/02/2014, 18:20
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Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf

Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf

... Yer- sinia, the increased synthesis of LcrV triggered by the activation of the system leads to the titration of LcrG, which binds LcrV in a 1 : 1 complex. In turn, this results in a release of the ... by the sug- gestion that pH sensing by Salmonella involves modi- fications in the assembly of the translocon, which affect the pH gradient within the needle,...
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition pdf

Tài liệu Báo cáo khoa học: Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition pdf

... 000 g for 10 min at 4 °C. The pellet, which contained the mitochondria, was resuspended in 30 lL of Mito-Cyto Buffer. The protein concentration was determined using the bicinchoninic acid method ... sequencing. The NdeI and BamHI restriction sites were used for cloning the PCR fragments into the His-tag vector, pET-15b. The recombinant proteins were generated in the E....
Ngày tải lên : 16/02/2014, 09:20
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