... containing atRE in the presence of
1m
M bipyridine (B) and liposomes containing atRE, in the presence
of 1 m
M bipyridine and 6 mM FeSO
4
(C). The generated retinoids
were analyzed by HPLC. The ... contribute to
providing chromophore to melanopsin to maintain
their light sensitivities. The expression and function of
RPE65c in other cell types in the retina remains to...
... Follistatin, Chordin and Noggin
[12]. These proteins are antagonists of BMP and other
members of the TGF-b family, binding to and inhibit-
ing these signaling molecules from binding to their
receptors ... their
receptors in the extracellular space, thus inhibiting ven-
tralizing activities. Of these proteins, Chordin has a
long-range effect. In Xenopus, expression of the...
... residues directly involved in ligand
binding, presumably abolishing the interaction with
signaling partners. The remaining mutations alter
amino acids located outside the ligand-binding pocket
and ... pro-
tein kinase B (PKB)]. In AKT, a cysteine substitution
of the corresponding R25 in the pleckstrin homology
(PH) domain also results in loss of function [16,17],
thereby...
... reaction of the luciferin ⁄ luciferase mixture, energy
donor (ATP) and oxygen results in the emission of light.
The intensity of the bioluminescence was detected using a
luminometer, and the mitochondrial ... in fatty acid utilization,
increase in glucose utilization) in the murine female
heart. Moreover, our data suggest that these changes
occur in an Akt-indepe...
... integrin-dependent
cell volume sensing and signaling integrates into the
overall context of insulin signaling. Similarly, sensing
of glutamine-induced hepatocyte swelling by integrins
feeds into ... hepatocyte swelling [12,13], insu-
lin-induced hepatocyte swelling is registrated by the
integrin system, leading to a Src-dependent activation
of the p38-type MAPK and thereby inhibit...
... covalently linked hairpins in the membrane
[10]. Importantly, the ion-binding site is not conserved
in hairpin one. If one assumes the same number of
transmembrane helices in V
0
and F
0
, the rotor of
eukaryal ... the densities correspond to the N- and
C-terminal helices of the c ring, respectively. The
C-terminal helices show a clear handedness, and two
of t...
... predicted to originate from an N-glycosyl
linkage between the anomeric carbon of the ribose,
which in the precursor NAD is linked to nicotinamide,
and the amino ⁄ imino group at C6 of the adenine
moiety ... between the anomeric
C1 of this ribose moiety (commonly termed ‘northern
ribose’ while the ribose linked to N9 of adenine is
called the ‘southern’ ribose; Fig. 1)...
... reaction intermediate, resulting in a reduction in
the lag phase of product accumulation, and an increase
in initial rate of product evolution. Furthermore, the
presence of ChlH increases the magnitude ... [14].
The current value is a better estimate of intermediate
accumulation, as the fit in Fig. 3B considers only the
evolution of intermediate. The rate consta...
... definite descrip-
tions and nicknames.
1 Introduction
Most of the existing approaches to opinion mining
propose algorithms that are independent of the text
genre, the topic and the target involved. ... reinforces
the idea that the real challenge in performing opi-
nion mining in certain realistic scenarios, such as
in user comments, is correctly identifying the lea...
... categories.
M
ethod
C
* there is telephone and the books on the desk.
Eb: The word in the beginning of the part which
should be replaced.
Ee: The word in the middle or the end of the part
which ...
word and the one preceding/ the targeted word
and the one following/ the targeted word and the
two preceding/ the targeted word and the two fol...