Tài liệu Báo cáo khoa học: Differential expression of duplicated LDH-A genes during temperature acclimation of weatherfish Misgurnus fossilis Functional consequences for the enzyme ppt

Tài liệu Báo cáo khoa học: Differential expression of duplicated LDH-A genes during temperature acclimation of weatherfish Misgurnus fossilis Functional consequences for the enzyme ppt

Tài liệu Báo cáo khoa học: Differential expression of duplicated LDH-A genes during temperature acclimation of weatherfish Misgurnus fossilis Functional consequences for the enzyme ppt

... 2007 The Authors Journal compilation ª 2007 FEBS 1513 Differential expression of duplicated LDH-A genes during temperature acclimation of weatherfish Misgurnus fossilis Functional consequences for ... white skeletal muscle of weatherfish, Misgurnus fossilis. Two isoforms of LDH-A mRNA were isolated and characterized: a short iso- form (mRNA a ldhÀa ¼...
Ngày tải lên : 19/02/2014, 02:20
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Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt

Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt

... subunits for catalysis, as expected. The tyrosyl radical of the R2F subunit was also monitored during the course of the enzyme assay. Curiously, under conditions where the product was formed, the ... species. Here, the source of the native R2F-protein of the C. ammonia- genes ribonucleotide reductase were transformants from the reintroduction of the nrd...
Ngày tải lên : 15/02/2014, 01:20
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Tài liệu Báo cáo khoa học: Differential effects of Mxi1-SRa and Mxi1-SRb in Myc antagonism ppt

Tài liệu Báo cáo khoa học: Differential effects of Mxi1-SRa and Mxi1-SRb in Myc antagonism ppt

... the possibility existed for dis- tinct functions for these two isoforms. In the present study, we have compared further the Mxi1-SRa and Mxi1-SRb isoforms at the levels of Myc antagonism in the ... assay. Expression constructs were generated encoding Myc-tagged versions of these two isoforms, as well as of the Mxi1-WR isoform that lacks the SID, and shown to give ris...
Ngày tải lên : 18/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism pptx

Tài liệu Báo cáo khoa học: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism pptx

... mark the boundary of the predicted substrate-binding pocket, reveals that some of them are conserved in the inac- tive isoform (i.e. Trp191 and Phe294). Even though the precise role of these ... a metal-ion cofactor and is able to take up the metal from the expressing host during protein synthesis [21,33], we investigated whether the production of the human recombina...
Ngày tải lên : 19/02/2014, 02:20
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Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

... with rabbit anti-mouse Igs for 30 min, followed by a further 30 min with the APAAP conjugate. These steps were repeated for 10 min each to increase the intensity of the sig- nal. After three additional ... loading of HepG2 cells resulted in increased expression of Nor3.2-reactive CD1d molecules at the plasma membrane. Expression of classical MHC class I and II molecule...
Ngày tải lên : 19/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx

... mediates activation of Ras subsequent to the stimulation of G i - and G q - coupled receptors [8,9]. The main mechanism for the activation of Ras- GRF1 is the binding of Ca 2+ ⁄ CaM to the N-terminal IQ ... [17,19]. The smaller iso- forms correspond to N-terminal deletions of the full- length 140 kDa protein. The physiological role of the guanine nucleotide exc...
Ngày tải lên : 19/02/2014, 18:20
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Tài liệu Báo cáo khoa học: Enhanced expression of Mcm proteins in cancer cells derived from uterine cervix docx

Tài liệu Báo cáo khoa học: Enhanced expression of Mcm proteins in cancer cells derived from uterine cervix docx

... several other transformed cell lines, although the extent of the enhancement varied among the cells. The enhanced level of Mcm expression in these transformed cell lines would contribute to the growth ... expressed in the larger nuclei of cancer cells compared with those in basal cells of the normal squamous cell epithelial layer (Fig. 7). The ubiquitous nature of...
Ngày tải lên : 20/02/2014, 23:20
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Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx

Tài liệu Báo cáo khoa học: EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors docx

... up-regulation of survivin expression [52]. The levels of cIAP-2 are down-regulated by gefitinib or erlotinib in intestinal epithelial cells [53]. Furthermore, the expression of cIAP-1 and of X-linked ... family genes and the phos- phorylation state of their proteins, thereby changing the amount and localization of Bcl-2 family members. However, each type of cancer h...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

... assembly of for- oxymithine by a synthetase lacking all E-domains. The lack of sequence information for the S. nitrosporeus genome impeded the identification of a biosynthetic machinery governing foroxymithine ... to the identification of the second siderophore (data not shown). We therefore assume that either the extraction conditions were inadequate for the iso- la...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition pdf

Tài liệu Báo cáo khoa học: Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition pdf

... decreasing the activity of caspase-3 in the three cell lines. Effect of HSS knockdown on CCCP-induced apoptosis To further elucidate the functional role of HSS in CCCP-induced apoptosis, the expression ... are the energy producers of the cell, and are essential for the maintenance of cell life. However, in the last 10 years, it has also become apparent that mit...
Ngày tải lên : 16/02/2014, 09:20
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