... production of inter-
leukins and secretion of immunoglobulins on the
mucosal surface of the intestine [49,50]. The antibacte-
rial defence of the intestinal mucosa depends in part
on stimulation of CCK ... euge-
nin, indicating that eugenin is indeed acting through
CCK
2
receptors.
To further investigate the interaction of eugenin with
CCK
2
receptors, we investigated...
... various chemokines stimu-
lated mainly by in ammatory cytokines, including IL-1b, TNF-a and
IFN-c. (B) Chemokines expressed in the joint recruit leukocytes into
the joints. In addition to functioning ... a
G-protein that transduces the intracellular signal. The
two major subclasses include the CC chemokines
(where the cysteines are neighboring) and the CXC
chemokine...
... 50–60% of the risk of devel-
oping RA. Thus, environmental factors may explain the remaining risk of
developing RA. A large variety of environmental factors such as infectious
agents, smoking, ... consequences of joint
destruction. Joint surgery is performed more frequently
in female RA patients than in male patients. In addition,
gender in uences the risk, as well a...
... control of their synthesis or activity,
including the inhibition of protein–protein interactions
in the activating signaling cascade of the transcription
factor of interest. Specific inhibitors ... tissue. These compounds bind
to two different intracellular proteins, namely FK506-
binding protein (FKBP) and cyclophilin, and the
drug–protein complex then binds to the interfa...
... attack of
the L-hOrn
3
a-amino group onto l-haOrn
4
. Taking
into account that the synthetases involved in the bio-
synthesis of the DKP-inheriting toxins thaxtomin
and fumitremorgin also contain ... pathogens, the interest in the structural
and functional characterization of these compounds is
growing and may result in the synthesis of specific
inhibitors based on...
... respectively. These
variations of the ratios of the metabolites suggest modifi-
cations in the catalytic mechanism responsible for the
metabolism of DDT.
Substrate binding
The substrate induced binding ... mutated
positions in CYP6A2 (helix J and vicinity of the b sheet 3–3).
These results are also original because this is the first
description of the role of mut...
... all the genes
involved in the pathway in the same operon; the cell
can then respond quickly to changes in the environ-
ment by changing the expression of only a few genes
and using the protein-synthesizing ... by the second gene in the las operon (Fig. 1).
In order to obtain strains with increased PK activity an
additional copy of the pyk gene was recombined...
... shifts the ratio between the strength (indica-
ted by the thickness of the curved arrows) of the cis and trans
interactions in favor of the latter. An increase in the trans inter-
action results in ... pairing between these sequences within
the BX-C plays a role in restricting the extent of loop-
ing-out domains.
Tethering elements
Deletion analysis of the...
... terminal in the grammar. If A
is a terminal then G
A
is the distribution that puts all
of its mass on the unit tree (i.e., tree consisting of a
single node) labeled A. If A is a nonterminal then
G
A
is ... parse of that
string with a PCFG approximation to the adaptor
grammar. This PCFG contains a production for each
adapted subtree in the parses of the other strings i...
... presented in one of
four colors indicating that they:
1. are not part of an NP either in the truth or
in the output of the person's rule set
2. consist of an NP both in the truth and in
the ... recall vs. the number
of appearances in the training set of each tag
sequence for the machine and the mean of the
top 3 students is shown in fi...