... ª 2009 The Authors Journal compilation ª 2009 FEBS
Nucleolin/C23 mediates the antiapoptotic effect of heat
shock protein 70 during oxidative stress
Bimei Jiang
1
, Bin Zhang
1
, Pengfei Liang
2
, ... among the regulation of nucleo-
lin ⁄ C23, the activation of caspase-3 and the induction
of apoptosis under the setting of oxidative stress and
Hsp...
... is
composed of residues 25–540. The overall structure of the
model of IPU and the mutated residues in this study are
shown in Fig. 3. To elucidate the mechanism of the
substrate recognition of IPU, ... panose (data not
shown).
Prediction of the positions of amino acid residues whose
substitutions resulted in the reduction of the IPU activity
While the study...
... we find: (i) Examination of 50% of the data
in the SLs leads to identification of between 75%
(AdjN) and 80% (PNV) of the TPs. (ii) For the
first 40% of the SLs, and lead to the worst
results, with ... fre-
quency) and the weak measures ( and ).
In the second half of the data in the SLs, how-
ever, there is virtually no difference between ,
, and the other measu...
... bc
1
sub-complex, but the presence
of only one of these two subunits does not substitute
for the other. After the addition of ISP, the binding of
the last subunit (i.e. Qcr10p) finally occurs. These find-
ings ... also
unknown. Furthermore, as in the case of the biogene-
sis of other multi-subunit complexes of the mitochon-
drial respiratory chain, the assistance...
... Fluorescence titration of the FMN domain
with the hMS AD.
Fig. S2. Comparison of the electrostatic potentials of
the surface of the CPR FMN domain and of a model
of the FMN domain of human MSR.
Fig. ... inset). The absorption
spectrum of the purified enzyme was typical of the
hydroxycobalamin form of the enzyme (Fig. 2). The
recovery of the activit...
... Gallery,
London, UK). (B) The colouring of the labellum (specialized median petal) of the flowers of the orchid Ophrys speculum closely resembles
the female wasp Colpa aurea, thus males of the species are ... that Darwin
was aware of neither Gregor Mendel’s laws of inheri-
tance [3] (which went all but unnoticed until their
rediscovery at the turn of the 20th cent...
... terminal in
the sinus gland, as a result of late and progressive
isomerization of the Phe3 of the CHH during the
migration of the secretion vesicles along the axonal
tract [39,41].
The immunohistochemical ... whereas
several somas of the two types were dispersed in the
X organ (Fig. 3A), most likely as a result of arte-
factual displacement of the cell bodi...
... Some of these
features can be traced in the sequences of hcHAT1
and hcHAT2 groups as well as of the ATG proteins
(Fig. 2), indicating evolutionary relationships of all
these enzymes and proteins ... is the
lack of domain B protruding out of the TIM barrel in
the place of loop 3 connecting the b3-strand to the
a3-helix [9,21]. Sharing domain B by rBATs and
GH13 enzy...
... Investigation of the effect of various phytoal-
exins on the activities of BHLmL2 and BHAb indicated that cyclobrassinin
was a competitive inhibitor of both enzymes. On the basis of pH depen-
dence, ... 97% inhibition of
BHLmL2 and BHAb, respectively.
The influence of pH on the activities of the BH
enzymes was investigated in the pH range 6–11. The
pH optima w...
... overexpression approach of
RpCAbr and RpCAtr, we cannot know the functional
effect of changes of some key amino-acids.
Origin and number of nonvertebrate CAs
Although the bootstrap values of the deep branches ... of the CA D. melanogaster
sequences and, on the other hand, the other
D. melanogaster sequences more closely related to the
CAVI vertebrate isoforms (CAa,...