... is so
long that
clinical
recovery
from
organophosphate exposure
is
usually dependent
on
synthesis
of new
enzyme.
This
process
may
take weeks
to
complete although
clinical
recovery
... effects
of
injected
cholinergic
drugs both peripherally
and on the
central nervous
system.
The
clinically
important actions
of
atropine
at
parasympathetic postganglionic nerve ending...
... respond
to
re-exposure
with clinical manifestations; most
of the UK
popula-
tion
has
antibodies
to
penicillins but,
fortunately,
comparatively
few
react clinically
to
penicillin
administration.
Whilst ... Adrenal
steroid
may be
useful.
DIAGNOSIS
OF
DRUG ALLERGY
This
still
depends
largely
on
clinical criteria,
history,
type
of
reaction, response
to
withdrawal
an...
... absorption
may be
clinically
important
in the
presence
of
coronary heart
disease (see above) although
it is
physiologically
insignificant
in
healthy young adults.
Nicotine
pharmacology
Pharmacokinetics
Nicotine
... legalisation
Dependence
Drugs
and
sport
Tobacco
Dependence
Nicotine
pharmacology
Effects
of
chronic smoking
Starting
and
stopping
use
Passive
smoking
Ethyl...
... as 11
weeks
before
10
consecutive
daily
tests
are
negative
(Ellis
G M et al
1986 Clinical
Pharmacology
and
Therapeutics
38:
572).
40
From
The
Alice
B
Toklas cook
book
1954 ... muscle (other than vascular muscle, which
is
discussed
above)
is
relaxed.
The
only important
clinical
use for
this action
is in
reversible airways
obstruction (asthma), when
the
actio...
... If the
exacerbation
lasts
for
more than
10
days, there
is a
need
for
clinical reassessment.
PNEUMONIAS
The
clinical setting
is a
useful
guide
to the
causal
organism
and
hence
... months.
All
short-course regimens include isoniazid, pyra-
zinamide
and
rifampicin.
After
extensive clinical
trials,
the
following
three have been found
satisfactory:
1.
An
unsupervis...
... effect.
Urinary
tract.
Any
contraction
of the
ureters
is
probably clinically unimportant. Retention
of
urine
may
occur (particularly
in
prostatic hypertrophy)
due to a mix of
spasm
of ... patients
of the
meaning
of the
pain;
it
comprises anxiety
and
fear
(particularly
in
acute
pain)
and
depression (particularly
in
chronic
pain),
which will
be
affected
by
patien...
... low
(1-1.25
mg
p.o.
at
night), increasing
at
approx-
imately
weekly intervals
and
according
to
clinical
response.
Nausea
and
vomiting
are the
commonest adverse
effects;
these
may
respond
... levodopa.
It
became
one of the
most
widely
prescribed drugs
for
Parkinson's disease.
Later
clinical trials, however,
failed
to
confirm
these
effects
and
indeed, c...