... interesting insights into views about financial development and theroleof the state in finance.Despite the crisis experience, 90 percent ofthe country officials and experts surveyed inthe ... underde-veloped institutional and legal settings. What istherole for the state in promoting financial infrastructure? The global financial crisis has highlighted the importance of a resilient financial infrastruc-ture ... markets, the basic measure of efficiency inthe stock market isthe turn-over ratio, that is, the ratio of turnover to capitalization inthe stock market. The ratio-nale of using this variable is...
... protein to be insertedinto the inner membrane, but it is missing a major portion of the domain localized inthe intermembrane space. Acomparison of all the known mammalian ESSS sequences is presented ... likely that the N-terminal domain is involved in protein–protein interactions with other hydrophilic domains of neighboring integral membrane subunits, and interspeciesinteractions are incompatible.From ... more integralmembrane proteins that are m issing inthe V79-G7, V79-G8,and V79-G18 mutants. It must still be determined whetherits absence inthe V79-G18 mutant isthe result ofthe missingESSS...
... theroleof this domain in the processing of membrane-tethered mucins. The mech-anism by which the heavily glycosylated portion of these molecules is released at epithelial surfaces within the ... frag-ments were then cloned into the SpeI ⁄ XhoI sites of the polylinker in MUC1FDTR. The remaining portions of the polylinker introduced leucine and valine residues N-ter-minal to the MUC3 and ... airway, the intestine and pancreatic ducts is of considerable significance inthe pathology of a number of diseases including cystic fibrosis and cancer.Equally important isthe fate ofthe cytoplasmic...
... assisting businesses in their provision of services to governmentCheyney UniversityDisadvantaged Business Enterprise – collaborating with business, industry and government agencies; providing ... UniversityRegional Learning Alliance – workforce development and training/collaborations with business and industry; meeting the training and education needs of businesses within 60 mile radius in Northern Allegheny ... UniversitySmall Business Initiative inthe Frehn Center for Management; offering information and assistance to individuals and groups planning to start a new businessIndirect Contributions...
... whendissecting the effect of GTP on glutamine-dependent CTPsynthesis.As mentioned inthe Introduction, the GTP activation of the E.coli enzyme is proposed to be due mainly to anincrease inthe ... analyzed the steady statekinetics ofthe glutaminase reaction of CTP synthase fromL. lactis in order to distinguish between the effects of GTP on the glutaminase reaction and the CTP synthesisreaction. ... role for GTP activation of CTP synthesis. A mechanism in which GTP only acts to increase the rate of hydrolysis of glutamine has some flaws in explaining the inhibition of DON-labeledenzymewhenassayedwithNH4Cl...
... resolution.Summarizing: summarizing involves extracting the key points from a discussion, organizing them, and restating them concisely.Observing: being able to watch and interpret whatis happening inthe ... 6 What istheroleofthe facilitator?How do facilitators help groups achieve their goals?They do it by • Clarifying and reinforcing the purpose ofthe group• Creating a welcoming and inclusive ... 5. Online Facilitation - 1. TheRoleofthe Facilitator – page 15SummaryFacilitation isthe key to building and sustaining an effective group. The main roleofthe facilitator is to help...
... importance ofthe Gly pair, located inthe vicinity of the active site ofthe cold adapted enzyme and to study itspotential roleinthe establishment of its psychrophiliccharacter.This work uses, in ... of the model, the behavior ofthe G261A variant can beinterpreted in terms of constraints introduced by the Alaside chain. The presence ofthe additional Gly at position261 possibly offers increased ... respectively. By introducing an Ala residue inthe place of Gly it is expected that the conformational flexibility of the main chain can be constrained with a minimum perturba-tion ofthe local structure,...
... smoke, questioning the accuracy of tobacco industry communications, and the declining social acceptability of smoking. Other forms of smoking-relevant advertising include advertisements for ... better in affecting target audience appraisals and indicators of message processing (such as recall ofthe advertisement, thinking more about it, discussing it) compared with other forms of ... Ph.D.Professor of MedicineDepartment of Medicine Division of CardiologyUniversity of California, San FranciscoSan Francisco, CAMarvin E. Goldberg, Ph.D.Irving and Irene Bard Professor of MarketingSmeal...
... watersheds, what isthe geographical scope ofthe factors contributing to or influencing these issues? (Mollinga et al 2007). The alternative option of a situational analysis of an individual ... trains a broad spectrum ofthe planning and engineering community inthe effective implementation of WSUD. The Partnership is proactively securing the implementation ofthe State Planning Policy ... economy. It is expected that the activity ofthe sector will increase in 2010, however this progression will be constrained by the strength ofthe Australian dollar, the increase ofthe price of air...
... sub-unit ofthe G protein and not inthe other case.Although there is discussion inthe literature concern-ing the possibilities of photoconversion of YFP into aCFP-like species during acceptor ... traf-ficking properties. The binding experiments alsopointed to a decrease inthe density ofthe D2R vari-ants inthe cellular membrane; the number of D2receptor binding sites decreased with the ... localization of these proteins inthe cell rather thanfrom the possible roleofthe D2R basic domain inthe mechanism of D1–D2receptor heterodimerization. However, we find that the acidicepitope...
... inthe glutamine (length ofthe side chainmaintained) and asparagine (shorter side chain)mutants, then trapping inthe absence of Vi nowoccurs [39] (Fig. 3); this is also the case when the ... crucial role. Anothernotable feature ofthe single-site IC mutants (including the glutamine substitutions) [39] isthe fact that, in the absence of Vi (± drugs) labeling ofthe enzymes with the ... the trypsin-sensitiveregion situated inthe linker domain of Abcb1a. Fol-lowing trapping inthe absence or presence of Vi andmild-trypsin treatment, the trypsin degradation pro-ducts of the...
... be interpreted bythis hypothesis. The hypothesis will also be extendedto the analysis ofthe possible roleof C-terminalmulti-helix domain in this process.Investigation of bacterial PAL structuresAs ... biosynthesis ofthe photoactive yellow proteinchromophore of these bacteria. The two recently discovered aminomutases, the phe-nylalanine 2,3-aminomutase (PAM) involved in taxolbiosynthesis in ... study the behavior ofthe Tyr110-loop in PAL in moredetail.Results and discussionModeling the active conformation of the essential Tyr110-loop of parsley PALBecause ofthe uncertainty of the...
... clarify the effect ofthe interface mutations on the antigen-binding affinity. To investigate systematically thisunsought relationship between the antigen-bindingaffinity of Fv and the VH⁄ VLinteraction ... However, as a result of covalentlinkage ofthe variable domains through the C-terminalconstant domains, not much is known about the distri-bution ofthe VH–VLinteraction strength in naturalB-cell ... to retain the specificity and affinity to antigen in itself [7,20]. Atleast for these antibodies, theroleofthe VLdomainmight be to increase the affinity by supporting the VHdomain. The phenomenon...
... Cardie, Vincent Ng, David Pierce,Chris Buckley. Ex-amining theroleof statistical and linguistic knowledgesources in a general-knowledge que stion answering sys-tem. In Proceedings ofthe 6th ... example, inthe case of questionQ209: “Who invented the paper clip ?”, the expected answer type is PERSON and so is the subject ofthe verb invented , lexicalized as the nominalization inventor. ... Reims?Q-711 :What are the names ofthe tourist attractions in Reims?Q-712 :What do most tourists visit in Reims?Q-713 :What attracts tourists to Reims?Q-714 :What are tourist attractions in Reims?Q-715:What...
... adopted the investments inthe pulp sector as a government project and have been promoting in several ways the consolidation of this sector in RS. These incentives include public financing lines ... “alleviating” poverty inthe country and allowing farmers to gain access into the cash economy. Policies promoted by this International Financial Institutions are the same old story. If there is ... mainly for the “problems” ofthe Southern area, an economically stagnated region with large areas of land, where cattle raising is declining. The opportunity arose during the last two administrations...