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utility of current sp c mouse models to explore pathogenic mechanisms and therapy for familial ild

Báo cáo khoa học:

Báo cáo khoa học: "Bench-to-bedside review: The role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury" pot

Báo cáo khoa học

... of the proapoptotic Bax/Bcl-2 ratio, and reduction of caspase-3 signaling, all of which decreased apoptosis Using an in vivo murine model of focal ischemic stroke, administration of mouse APC ... sealed cell-cell contacts Using a cleavage site specific antibody to PAR1, the endothelial protective effects of APC and the endothelial disruptive effects of thrombin could both be blocked, which ... dependent and is therefore a good choice for testing the direct and indirect effects of APC on the lung microvasculature Mice were given acid intratracheally and were then treated with murine APC In...
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Báo cáo khoa học: Intrinsic local disorder and a network of charge–charge interactions are key to actinoporin membrane disruption and cytotoxicity ppt

Báo cáo khoa học: Intrinsic local disorder and a network of charge–charge interactions are key to actinoporin membrane disruption and cytotoxicity ppt

Báo cáo khoa học

... a conformational exchange process on the microsecond–millisecond time scale Fig Comparison of the loop regions located in the mutation face for the X-ray structure of wild-type StnII (A) and for ... in close contact with the membranes, can play critical roles in the overall toxic mechanism of StnII These results are relevant not only for the characterization of the molecular interactions of ... structure and dynamics of its local environment and the four nearby loops but also the conformation of sequence stretches located near the C- terminus of the molecule All these loops and stretches...
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báo cáo hóa học:

báo cáo hóa học:" Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients" potx

Hóa học - Dầu khí

... demographic and clinicopathologic characteristics were calculated for the study cohort Associations between IGFBP-3 and -4 expression and age, gender, tumor thickness, histopathologic subtype, and ... analysis and interpretation of data and the writing of this manuscript PJC performed all statistical analyses FD and HK reviewed all specimens for clinicopathological data and tumor content HY scored ... Debacq-Chainiaux F, Pascal T, Boilan E, Bastin C, Bauwens E, Toussaint O: Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of...
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Báo cáo nghiên cứu nông nghiệp

Báo cáo nghiên cứu nông nghiệp " Increasing the capacity of the Food Crops Research Institute to enhance the Production and Management of Potatoes in the Red River Delta " pot

Báo cáo khoa học

... Outputs and Performance indicators Outputs Performance Indicators ♦ Survey of crops in the first year will achieve the i) Publication of survey results of objective of training FCRI staff to identify ... description Identification of major factors limiting marketable yield Post harvest technology to extend storage and Performance Performance indicators rating Crop Survey to train Publication of ... project manager and actions carried out accordingly 3.6 Technical assistance, training and capacity building The bulk of training provided by the project was through collaborative research Researchers...
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Báo cáo khoa học:

Báo cáo khoa học: "Comparative antibody response of five recombinant antigens in related to bacterial shedding levels and development of serological diagnosis based on 35 kDa antigen for Mycobacterium avium subsp. Paratuberculosis" pot

Báo cáo khoa học

... primers for SOD, forward 5'CAT ATG GCT GAA TAC ACC CTG CCC GA3' and reverse 5'CTC GAG TCA GCC GAA GAT CAG GCC TT3' PCR was performed as previously described [9] The PCR products of each gene were cut ... (85A, 85B and 8 5C) were prepared as previously described (10) The specific primers for 35 kDa, forward 5'CAT ATG ACG TCG GCT CAA AAT G3' and reverse 5'GAA TTC TCA CTT GTA CTC ATG GAA CTG3' The ... rate (1-specificity) that is obtained at each cut-off point) was constructed and the area under the curve (AUC) value was calculated as a measure of the accuracy of the test Also, ELISA was compared...
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Báo cáo y học:

Báo cáo y học: "Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes" ppsx

Báo cáo khoa học

... II collagen Collagen-induced arthritis development and antibody responses to type II collagen in the C5 , C6 , C9 , C1 0, and C1 1 congenic mice Investigation of CIA development in C5 congenic mice ... the offspring The C6 , C1 0 and C1 1 were generated by backcrossing C5 congenic mice to the B10.RIII parental strain followed by intercrossing of the offspring Stars indicate significant differences ... littermate controls for mice with the C5 congenic (a/b) fragment cB10.RIII = littermate controls for mice with the C6 , C9 , C1 0 and C1 1 congenic (a/b) fragment dThe day for onset of disease eMean ± standard...
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Báo cáo y học:

Báo cáo y học: "Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes" doc

Báo cáo khoa học

... II collagen Collagen-induced arthritis development and antibody responses to type II collagen in the C5 , C6 , C9 , C1 0, and C1 1 congenic mice Investigation of CIA development in C5 congenic mice ... the offspring The C6 , C1 0 and C1 1 were generated by backcrossing C5 congenic mice to the B10.RIII parental strain followed by intercrossing of the offspring Stars indicate significant differences ... littermate controls for mice with the C5 congenic (a/b) fragment cB10.RIII = littermate controls for mice with the C6 , C9 , C1 0 and C1 1 congenic (a/b) fragment dThe day for onset of disease eMean ± standard...
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Báo cáo sinh học:

Báo cáo sinh học: "Resistance of livestock to viruses: mechanisms and strategies for genetic engineering" doc

Báo cáo khoa học

... antireceptors may have several domains, each reacting with a different receptor Mutations of receptors may cause a loss of the capacity of a receptor and antireceptor to interact and thus lead to ... through a specific binding of a virion protein, the antireceptor, to a constituent of the cell surface, the receptor Complex viruses, such as vaccinia, may have more than one species of antireceptor ... alteration of the structure or function of the infected cell - the effects may range from cell destruction to subtle, but significant changes in function and antigenic specificity of infected cells...
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báo cáo khoa học:

báo cáo khoa học: " Defining the effect and mediators of two knowledge translation strategies designed to alter knowledge, intent and clinical utilization of rehabilitation outcome measures: a study protocol [NCT00298727]" docx

Báo cáo khoa học

... fundamental to advancing clinical practice and research The current use of patient-oriented outcome measures in research and practice is deficient, despite the fact that health care professionals recognize ... application to clinical reasoning This focus includes the clinician's ability to provide: a rationale for why specific outcome measures were selected for specific patients, an understanding of ... spectrum of behaviors consistent with the Transtheoretical Model of (Readiness to) Change; and To determine the relative importance of potential predictors of change, including characteristics...
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báo cáo khoa học:

báo cáo khoa học: " Utility of EST-derived SSR in cultivated peanut (Arachis hypogaea L.) and Arachis wild species" potx

Báo cáo khoa học

... AAT/ATT ACC/GGT ACG/CTG ACT/ATG AGC/CGT AGG/CCT AGT/ATC CCG/CGG AAAG/CTTT AAAT/ATTT AATC/AGTT AATT/AATT ACAT/ATGT AAAAG/CTTTT AAAAT/ATTTT AGTAT/ATATC AAAAAG/CTTTTT AAGACG/CTGCTT AATAGT/ATCATT AATGAT/ACTATT ... Wild species Di 288 AC/GT AG/CT AT/AT Tri 55 14 218 56 563 AAC/GTT AAG/CTT AAT/ATT ACC/GGT ACG/CTG ACT/ATG AGC/CGT AGG/CCT AGT/ATC CCG/CGG 15 AAAG/CTTT AAAT/ATTT AATC/AGTT AATT/AATT ACAT/ATGT ... twenty-two accessions of cultivated peanut(A.hypogaea L.) corresponding to two subspecies (hypogaea and fastigiata) and sixteen accessions of wild species from seven sections of the genus Arachis were...
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Báo cáo y học:

Báo cáo y học: "Bench-to-bedside review: Mechanisms and management of hyperthermia due to toxicity" doc

Báo cáo khoa học

... Critical Care Medicine of the Society of Critical Care Medicine in collaboration with the Infectious Disease Society of America Crit Care Med 1998, 26:392-408 Lowell BB, Spiegelman BM: Towards ... consequence of uncoupling Hemodialysis is the treatment of choice both for enhancing the clearance and as a possibility to cool down the blood during extracorporeal circulation Besides other clinical ... interactions between drugs It is not an idiopathic drug reaction but a predictable consequence of excess serotonergic agonsim of central and peripheral serotonergic receptors [37] In the central...
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Báo cáo y học:

Báo cáo y học: "Use of the probiotic Lactobacillus plantarum 299 to reduce pathogenic bacteria in the oropharynx of intubated patients: a randomised controlled open pilot study" pps

Báo cáo khoa học

... quantification of total CFU of lactobacilli and identification of Lp299 Viable counts of all lactobacilli were obtained on Rogosa agar (Oxoid, Basingstoke, Hampshire, England) incubated anaerobically ... Serratia species 0 0 0 20 Stenotrophomonas maltophilia 0 0 1 21 Streptococcus agalactiae 1 0 0 22 Enterococcus faecalis 0 3 0 23Enterococcus faecium 1 0 7–23 Enteric bacteria 6 11 17 12 24 Candida ... samples Species Inclusion Tracheal secretions Subsequent Inclusion Subsequent Lp C Lp C Lp C Lp C Haemophilus influenzae 0 2 Moraxella catarrhalis 0 0 1 Beta-Streptococcus group G 1 0 0 Streptococcus...
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Rise of the machines moving from hype to reality in the burgeoning market for machine to machine communication

Rise of the machines moving from hype to reality in the burgeoning market for machine to machine communication

Tổng hợp

... need to experiment through pilots and close attention to customer feedback to understand what customers will accept Firms need to innovate within sectors, but many sceptics remain to be convinced ... devices; highly complex ecosystem to connect between doctors, hospitals, ambulances, care homes and more Example of successful M2M application: Vitality GlowCaps, a connected pillbox that tracks ... pilots and close attention to customer feedback to understand what customers will accept Just as the emergence of social networking has created a debate about the boundaries of privacy in society,...
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Proteomic analysis of the response of murine bone marrow derived macrophages to IFN y stimulation and infection with staphylococcus aureus

Proteomic analysis of the response of murine bone marrow derived macrophages to IFN y stimulation and infection with staphylococcus aureus

Tổng hợp

... ACTB CATB CATS ACTG CATB ACTG CAZA1 CLIC1 CATZ PDIA1 ACTG VA0D2 PDIA1 VIME TBB2A GRP78 VIME SPB6 ARP3 HSP 7C "ACTB, CATZ" ACTB ACTG CATB "ACTG, CATD" ACTG RAB1B ACTB "ACTB, PDIA3" "ACTB, ARPC2" ... stimulation of cytotoxic effector mechanism Antigen-MHC class II molecule complexes are recognized by CD4+ T cells Activation of CD4+ T cells can initiate a T helper cell response, B-cell activation, and ... due to the natural modifications of cell wall components, lipoteichoic acid and membrane phospholipid, for example, D-alanine substitutions of ribitol teichoic acid and lipoteichoic acid and...
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Adapting to Web Standards: CSS and Ajax for Big Site pot

Adapting to Web Standards: CSS and Ajax for Big Site pot

Kỹ thuật lập trình

... Microformats for Conventions, Meaning, and Utility Microformats and POSH Too Much Class Classic Classitis Curing Classitis CSS File Content Structure ... reuse and consistency ❖ Reduced bandwidth use and caching of style and script files ❖ Faster rendering of pages ❖ Cleaner, easier -to- maintain code Part I Introduction ❖ Easier to make accessible for ... introduces more rigid understandings of the specifications Based on further research of the standards, browser manufacturers have attempted to get closer to the strict exactitude of the specifications...
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No Holds Barred Fighting: The Ultimate Guide to Conditioning Elite Exercises and Training for NHB Competition and Total Fitness pot

No Holds Barred Fighting: The Ultimate Guide to Conditioning Elite Exercises and Training for NHB Competition and Total Fitness pot

Du lịch

... to focus on a specific aspect of the twin sports of NHB/submission wrestling and to give thoughtful consideration to the necessary ideas, tactics and strategies pertinent to that facet of focus ... digestible Counting 2-count, push-ups Starting from the top of the exercise, we descend to brush our chest to the floor for a count of and return to the top of the exercise for a count of Push-ups ... ideas on constructing a routine, and of course, specifics to directly complement the NHB/MMA game.This book, while comprehensive in its approach to the topic at hand, is by no stretch of the imagination...
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Báo cáo khoa học:

Báo cáo khoa học: "USING AN ONLINE DICTIONARY TO FIND RHYMING WORDS AND PRONUNCIATIONS FOR UNKNOWN WORDS " doc

Báo cáo khoa học

... COMMAND: DIM1: P O U C RNN DIM2: R Y E HM DIM3: REVERSE insurgency deficiency efficiency inefficiency sufficiency insufficiency proficiency expediency inexpediency resiliency leniency conveniency ... stringency urethra decumbency astringency urethrae recumbency contingency incumbency urethral pungency urethritis redundancy cogency urethroscope fervency emergency urethroscopic conservancy detergency ... urinometric detergency surgeoncy insurgency convergency emergency indeterminacy pertinency impertinency repugnancy permanency impermanency currency trustworthy twopenny company APPLICATION: PRONUNC COMMAND:...
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new riders publishing adapting to web standards css and ajax for big sites

new riders publishing adapting to web standards css and ajax for big sites

Tin học

... Microformats for Conventions, Meaning, and Utility Microformats and POSH Too Much Class Classic Classitis Curing Classitis CSS File Content Structure ... reuse and consistency ❖ Reduced bandwidth use and caching of style and script files ❖ Faster rendering of pages ❖ Cleaner, easier -to- maintain code Part I Introduction ❖ Easier to make accessible for ... introduces more rigid understandings of the specifications Based on further research of the standards, browser manufacturers have attempted to get closer to the strict exactitude of the specifications...
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báo cáo hóa học:

báo cáo hóa học:" Evaluation of the late life disability instrument in the lifestyle interventions and independence for elders pilot (LIFE-P) study" ppt

Hóa học - Dầu khí

... part in an exercise program 0.67 0.66 0.24 Take care of inside of home 0.69 0.59 0.38 c Month 12 Follow-Up One factor Items Two factor One factor Two factor Factor Factor Factor Social role Visit ... 0.74 0.68 0.09 0.57 0.26 0.56 Take care of inside of home 0.68 0.61 0.32 b Month Follow-Up One factor Items Two factor One factor Two factor Factor Factor Factor Social role Personal role Visit friends ... physical activity Detailed inclusion/exclusion criteria and a flow diagram regarding to the specific numbers of individuals screened and reasons for exclusion can be found in an earlier publication...
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