the synthesis of the modified tetrapyrrole known asd1haem requires several dedicated proteins which are coded for by a set of genes that are often found adjacent to the structural gene
... ofa monolayer of inner
circular muscle, which makes its wall weak, as com-
pared tothe small intestine that is formed ofthe inner
circular and outer longitudinal muscle layers. The
vasa ... recta, which supply the mucosa and submucosa
of the colon, penetrate the circular muscle. The
weakness ofthe vascular portals in the circular muscle
possibly causes mucosal herniation into the ... owing to incomplete bowel preparation. The
bleeding was controlled by #3-0 Vycryl intracorporeal
suture, and the invagination ofthe diverticulum was
performed laparoscopically. The recovery was...
... orientation
(Figs2and 3A) .Ofthese,five(ataP3, ataP5, ataP4, ataP10
and ataP7) are highly similar toknown or putative genes
thatareknown or proposed to be implicated in the
biosynthesis ofthe aminonucleoside ... pur
cluster of S. alboniger [6]. They were accordingly named
ataP3, ataP5, ataP4, ataP10 and ataP7. The two additional
ones were named ata12 and ataPKS1 (Figs 2 and 3). All
shared a codon usage and a G+C ... recombinant DNA techniques that are
employed to prepare specific mutants. Therefore, we used
the latter approach to identify the function ofseveral ataP
genes by analyzing the complementation of S. alboniger
strain...
... Chart 3
illustrates the magnitude of DAC bilateral donor
commitments tothe ICT infrastructure in total values and as a share of DAC countries’ total
bilateral sector allocable ODA. Over the ... period 1990 to 2002, the share of aid forthe ICT
infrastructure dropped from a high of 4.5% of total bilateral sector allocable ODA toa low of
only 0.6% in 2002.
The rationale forthe decline ...
recognition ofthe crucial role of basic and advanced communication and information
capabilities as a tool for development. This recognition includes awareness ofthe gaps that
continue to exist in access...
... end
The contact area ofthe Nt amidinium end (NAE) was
investigated by evaluating the interaction energies and
hydrogen positions ofthe end fragment and the bases
of base pair T8 -A2 5 and base ... more
efficiently than do alternating ATAT tracts [6,7],
resulting in a preference for binding tothe DNA
in the order AATT > TAAT ¼ TTAA ¼ ATAT >
TATA [8].
For AATT tracts, binding ofthe drug can be ... bifurcated hydrogen
bonds are formed between the amide nitrogen atoms ofthe drug and the
N3 and O2 atoms ofA and T base pairs, respectively, clearly cataloging
the structure to class I. As the...
... Recorder also allows users to add
utterances of their choice tothe corpus of speech
for the synthetic voice. These utterances are those
the user wants to be synthesized clearly and will
automatically ...
has become intricately associated with their identi-
ty is not only traumatic tothe individual but to
family and friends as well.
A form ofsynthesisthat incorporates the quali-
ties of ... are automatical-
ly stored with broad phonetic labels. The automatic
saving function will reduce the time of recordings
and the potential risk for miscataloging the files.
Currently, the automatic...
... eIF 2a- kinases could be explained by the
innate adaptor function of Nck. For example, Nck is
known to translocate specific effectors toa subset of
activated receptor tyrosine kinases at the plasma
membrane ... mediating
the activation of eIF 2a- kinases.
Nck fails to alter GCN2-mediated eIF2aSer51
phosphorylation
To ascertain thatthe effect of Nck-1 on eIF2aSer51
phosphorylation by eIF 2a- kinases is a general ... activation of these proteins.
In addition to its regulation by eIF 2a- kinases, the lev-
els of eIF2aSer51 phosphorylation are also controlled
by eIF 2a- phosphatase activities that specifically
dephosphorylate...
... Institutional Review Board
and bythe director ofthe hospital. At the time ofthe study
for women to have a companion during labor was not a
policy at that institution, as it is still not forthe majority
of ... one hand there is a general
belief thata labor companion has always positive effects,
there are, , on the other hand still a lot of health facilities
where companions are not allowed, especially ... or fetal distress.
Exclusion criteria were: unavailability ofa companion;
fetal malformation; maternal disease and/or indication
for elective Caesarean section.
The study was approved bythe Institutional...
... in place of saturated fatty
acids. It is possible to increase the content of vitamin E, a natural antioxidant,
and to insert the capability of producing plant-based omega-3 fatty acids
into oil ... therefore, the Þnal assess-
ment of safety is always comparative.
The scientiÞc basis ofthe evaluation process is the concept of “substantial
equivalence.” Regulatory agencies compare GM crops to their ... mutagenesis, create signiÞcant changes in
the genetic makeup of plants and animals due tothe random recombination
and sorting of thousands of genes. As a result of intervention by people, the
hybrid...
... following the uptake of satu-
rated and unsaturated FFAs into the cells. After their
internalization, FFAs are converted to fatty acyl-CoA,
a reaction catalyzed by ACS. Fatty acyl-CoAs are acti-
vated ... manifestation of toxicity. It has to be noted
that TrC was not able to inhibit thapsigargin-induced
Ctrl
3 h
12 h
24 h 36 h
6 h
OA
OA
SA/OA
SA/OA
SA/OA
SA/OA
SA/OA
SA
OA
FL1-Log
Counts
OA
OA
SA
SA
SA
SA
Ctrl
Ctrl
Ctrl
Ctrl
Ctrl
SA ... reticulum
stress-mediated and mitochondrial-mediated apoptosis; (c) the activation of
stearate in the form of stearoyl-CoA was a necessary step forthe lipotoxic
effect; (d) the capacity of cells to produce and accumulate...
... 5¢-ATA
CCATGGACAAAACCCACAGTACAATG
P1OH 5¢-
CATATGCACAAAACCCACAGTAC
P2O 5¢-TAT
GGATCCTTAATTAGAAACAAACTGTCTGA
TAAAC
P2OH 5¢-
CTCGAGATTAGAAACAAACTGTCTGATAAACC
P1Z 5¢-ATA
CCATGGCTGGAGAAGACTTTAAGATC
P1ZH ... 5¢-
CATATGACTGGAGACTTTAAGATC
P2Z 5¢-TAT
GGATCCTCACCACCCAATTTCGGAAAG
P2ZH 5¢-
CTCGAGCCACCCAATTTCGGAAAGT
Table 2. Over-expression plasmids for Sno1p and Snz1p prepared in this
study. Symbols O, Z and ... dehydrogenase at 37 °C for 90 min.
After centrifugation (14 000 g) for 1 min, the absorbance of
the supernatant was read at 363 nm. The absorbance of
the reduced form of APAD (APADH) was linear over the
2–100...
... (–)IRES.
RNA synthesis obtained with the (–)IRES 104 RNA
was only 24% ofthatofthe wild-type (–)IRES RNA,
a value similar tothatofthe (–)IRES 219 RNA. The
fact thatthe (–)IRES 104 can be used as a ... minus-strand
RNA that serves as a template forthesynthesis of
new plus-strand RNA molecules. Initiation of RNA
synthesis at the 3¢-end ofthe plus- and minus-strand
RNA most probably involves interactions ... template by
the recombinant HCV NS5B differed from the data
obtained by Oh et al. [18]. These authors showed that
the 122 nt ofthe 3¢-end ofthe HCV minus-strand
RNA was unable to sustain RNA synthesis. ...