the discovery that micrornas mirnas are synthesized as hairpincontaining precursors and share many features has stimulated the development of several computational approaches for identifying new mirna genes in various animal species
Tài liệu Báo cáo khoa học: Treatment of neutral glycosphingolipid lysosomal storage diseases via inhibition of the ABC drug transporter, MDR1 Cyclosporin A can lower serum and liver globotriaosyl ceramide levels in the Fabry mouse model doc
... the first glycosyl transferase required for the synthesis of most GSLs, including Gb3 (in Fabrydisease) and of course, GlcCer (in Gaucher disease). Byinhibiting this enzyme, the synthesis of ... applied for 30 s; excess staining was removed by immersing sections in distilled water for 4 min and ‘blued’ by immersing in tapwater for 4 min. Sections were then dehydrated for 2 min. in each of ... with 2 mL of chloroform ⁄ methanol (2 : 1 v ⁄ v) per 100 lL of plasma and then partitioned against 1 ⁄ 5 volume of water. The lowerphase was dried under a stream of nitrogen gas and then the residue...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... β-glucosidases in the intestine and can be adminis-tered orally [27]. Therefore, the aim of the present study was to evaluate the inhibitory effect of some thioglycosides synthesized in our ... and luminescence for ATP detection was assessed using a MicroBeta Trilux (PerkinElmer). A standard curve was used to determine the amount of ATP in mg of protein measured from the number of ... used as standard therapeutic agents for the treatment of dia-betes [7]. The mechanism of action of the anti-diabetic agents used for the treatment of type 2 diabetes, in- clude increasing insulin...
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Kết cấu vận luật của thể song thất lục bát trong tiến trình phát triển thể loại ngâm khúc
... lá đan sàng nên chăng? Đan sàng thiếp cũng xin vâng, Tre non đủ lá nên chăng hỡi chàng. [39, 232] (ký hiệu in đậm VD: ôi Vần chân ; ký hiệu in đậm, gạch chân VD: im: vần lưng) Nhƣ vậy, ... các công trình nhƣ : Chinh phụ ngâm khảo thích và giới thiệu (Nhà xuất bản văn hóa HN 1964) của Lại Ngọc Cang; Cung oán ngâm khúc khảo thích chú giải (Hà Nội 1931) của Đinh Xuân Hội; Cung oán ... (N.I.Niculin), Tiếng khóc nhân loại trong tiếng khóc Nguyễn Gia Thiều (Vũ Khiêu), các bài viết của các tác giả Phạm Luận, Đặng Thanh Lê, Nguyễn Lộc… trong các giáo trình văn học Việt Nam về Chinh...
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Lấp đầy khoảng trống giữa thế giới thật và ảo thông qua tiếp thị
... TIẾP THỊ LANTABRAND – Total Brand Solution Tel: (08) 9 409 781 Fax: (08) 9 409 780 info@lantabrand.com www.lantabrand.com 5 Christopher Klaus, người sáng lập ... mọi người tham gia vào xã hội tưởng tượng và những kinh ngiệm kinh doanh trong môi trường ảo. Whyville.net đặt tại Pasadena, California, là thế giới giáo dục ảo cho thanh thiếu niên. Hơn 2,1 ... họ chính là những “kinh nghiệm” hấp dẫn không giống như bất kỳ phương tiện truyền thông nào. Theo Jose Pablo Zaga, ứng viên tiến sĩ tại trường Cao đẳng Công nghệ thông tin, Viện công nghệ...
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Flavor enhancement as a tool for increasing pleasantness and intakeof a snack product among the elderly
... itself instead of that of the products, when they are asked how bored they are with the studied products. In the present study, neither the boredom ratings increased nor the hedonic ratings decreasedduring ... time of the day they wanted. Similarly to the tasting sessions, the odor intensity was rated right after opening the lid, and the pleasantness and flavor intensity after tasting 3–4spoonfuls of the ... in the within-groups degrees of freedomassociated with F-values is due to some missing values in the data of the elderly. In the case of intake, there was alsomissing data from the young. The...
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Nature''s templates - identifying the patterns that control events
... problems are unique, something that experienced managers know intuitively. If reinforcing and balancing feedback and delays are like the nouns and verbs of systems thinking, then the systems ... elements of the reinforcing and balancing loops:8 First, identify the reinforcing process—what is getting better and what is the action of activity leading to improvement? (There may be other ... relieving the stress. The problem comes back, and so does the need for drinking. Insidiously, the shifting the burden structure, if not interrupted, generates forces that are all-too-familiar in...
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Tài liệu NGỮ PHÁP LỚP 12 (CONT) SO THAT/IN ORDER THAT IN ORDER TO/SO AS TO/TO docx
... want to pass the exam. I study hard .I want to pass the exam. -> I study hard in order to pass the exam. NGỮ PHÁP LỚP 12 (CONT) SO THAT/ IN ORDER THAT IN ORDER TO/SO AS TO/TO ... don't want to fail the exam. -> -> I study hard in order not to pass the exam. đúng -> I study hard so as not to /to pass the exam.đúng -> I study hard not to pass the exam. sai ... can't/couldn't. I study hard so that I can pass the exam. I study hard so that I won't fail the exam. I hide the toy so that my mother can't see it. ( tôi giấu món đồ...
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Tài liệu The Culture That Gave Rise To The Current Financial Crisis pptx
... other clients of the manager.(6) In all, measuring up to the 1940 Act standard that funds are in fact “organized, operated, and managed in the interest of their shareholders,” by eliminating ... how the erosion in the conduct, values, and ethics of business that I have described has been fostered by the profound and largely unnoticed—change that has taken place in the nature of our financial ... business corporations in whose shares they invest also honor their own fiduciary duty to the holders of their shares. Finally, it is these two groups that share the responsibility for the prudent stewardship...
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Tài liệu Implement the Methods That Update the Database pptx
... and a string as their parameters, as long as one method has a string as the first parameter, and the other has an integer as the first parameter-like the first two methods in Listing 9.27. It ... of updating and deleting rows in the database, you will need to implement the Save and Delete methods that are defined in the ICustomer interface. To insert new rows into the database, you'll ... otherwise-based on the order of the datatypes in the parameter list, and not the names of the parameters. In other words, you can have two overloaded methods that take an integer and a string...
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Tài liệu ANTHROPOLOGY: AS A SCIENCE AND AS A BRANCH OF UNIVERSITY EDUCATION IN THE UNITED STATES pptx
... The Origin and Subdivisions of Races. Theories of monogenism and polygenism. Doctrine of “geographical provinces” or “areas of characterization.” The continental areas at the date of man’s ... records of the development and the decline of peoples; and what constitutes a “people,” and shapes its destiny, is the very business of Ethnology to explain. So likewise in hygiene and medicine, in ... observation and experimental research, embracing all his nature and all the manifestations of his activity, in the past as well as in the present, the whole co-ordinated in accordance with the inductive...
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Tài liệu THE DISCOVERY OF THE SOURCE OF THE NILE docx
... females, the sons work for the household until they marry, and in after life take care of their parents in the same way as in the first instance the parents took care of them. Twins are usually ... which, scared by the interminable singing, shouting, bell-jingling, horn-blowing, and other such merry noises of the moving caravan, could be seen disappearing in the distance. Leaving the park, ... trader was just then leaving for Zanzibar. In this dilemma it appeared that I must inevitably lose the travelling season, and come in for the droughts and famines. The tide, however, turned in my...
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Tài liệu The Things that Make Me Weak and Strange Get pptx
... started there and had crept up and down as low as 70 and as high as 88, depending on how he was do-ing in the rest of his life. Zbigkrot was active in the gardens, both the bigones where they ... bytes was long gone, butit was the kind of thing that the Order handled on a routine basis: given the timing and other characteristics, Lawrence thought it was probably astream of purchase data ... thoughts and the deepening throb from his face, his knees, the palms of his hands. Hishands and knees had been sanded raw and there was grit and glass and bits of pebble embedded under the skin,...
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Tài liệu Ghost Wave - The Discovery of Cortes Bank and the Biggest Wave on Earth pptx
... front of you. And everything was in motion the boat and the buoys—everything. I remember just sitting out there after the set passed and thinking, We’re in another world.” As if to punctuate the ... gunned the boat’s engine and ran for deeper water just off to the west of the peak, while instinct again took over for Sharp and Hulse. Being caught inside involved the same drill whether you ... me the difference between making a life and making a living. Quinn, for teaching me the meaning of love.Fritz and Lucy, for teaching me the meaning of life. My sincere apologies to anyone I...
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- micrornas mirnas are noncoding regulatory rnas that function via the degradation of target mrnas and inhibition of translation they are found widely in higher eukaryotic organisms
- resulting in dramatic increases in healthcare costs understanding the processes and metabolic perturbations that contribute to the expansion of adipose depots accompanying obesity is central to the development of appropriate therapeutic strategies
- was recently identified in human peripheral blood monocytes treated with monocyte chemotactic protein 1 mcp1 and in human monocytederived macrophages stimulated with interleukin il1b these experiments revealed that the gene undergoes rapid and potent
- and within each tooth category by the morphs into which these teeth appear to fall note that there are occasional duplications of specimen numbers we recognize three major dental morphs one ofthese morph 1 does indeed represent the extant orangutan pong
- the ties that bind
- periurban and urban consumers on the reasons for not consuming organic products the two main reasons advanced is that organic products are expensive according to 60 of the consumers in the transkei
- 625 of periurban consumers and 818 of urban consumers see table 1 the second reason advanced is that organic products are not readily available according to 60 of the consumers in the transkei
- diseases and disorders of the eye are listed as mdc 4
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25