... of the structure to explain what was already known about this type of protein is beyond me In an era when experimental details are relegated to ‘Supplemental material’, especially inthe vanity ... stating where the papers were published is a surrogate for actually having read them I’m ashamed to say I’ve done that myself Does being the first into print mean more than publishing the best ... unless they felt the need to beat their competitors and to have their work published ina journal with as high a profile as possible I think that feeling is often self-defeating, as it clearly was...
... whenthe individual has no outward manifestations of the disease In about six weeks after the chancre the so-called secondary symptoms make their appearance They are heralded by headache, pains ... the plant passing into a resting stage from which it awakes the following spring to repeat again its annual cycle If he observes an animal he finds that it similarly develops toa stage of maturity, ... due toa lengthening of the thigh and leg bones In serial homology withthe thigh and leg arethe bones of the arm and we find that these are undergoing an increase in length commensurate with the...
... two activator-binding domains might be an adaptation tothe fact that activators generally bind DNA as dimers, withthe result that two activation domains are available to recruit target factors ... suggest that the predominant coactivating role of SWI ⁄ SNF may be at steps downstream of activator binding rather than as a facilitator of activator binding, although these roles are not mutually ... help to explain how activator proteins are able to form specific interactions withthe large range of structurally distinct factors that they recruit to target genes The Swi1 and Snf5 activator-binding...
... Phosphatase-treated nuclear extracts were assayed for their DNA-binding capacity in standard EMSA UV crosslinking of DNA–protein adduct The EMSA reaction was carried out using ng labelled Jun)25 and ... intestine alkaline phosphatase (shown at the top) prior to its addition to EMSA Lane shows the complex formed between RNE-d treated with heat inactivated alkaline phosphatase (10 U) and labelled ... (15% acrylamide) and analysed by autoradiography changes of · binding buffer over a period of 30 and autoradiographed Affinity purification of the factor(s) interacting withthe )148 to )124 region...
... data analysis and review BR, JB involved in drafting and reviewing the manuscript KFO, TO, ES involved in reviewing the manuscript Acknowledgements Assistance with data for the sample frame was ... Mental health, social functioning, and disability in postwar Afghanistan JAMA 2004, 292(5) :575 -584 Lopes Cardozo B, Vergara A, Agani F, Gotway CA: Mental health, social functioning, and attitudes ... References 10 11 Boas MHA: Northern Uganda IDP Profiling Kampala: UNDP/ GoU/FAFO; 2005 Internally Displaced Camps in Lira and Pader, Northern Uganda A Baseline Health Survey Preliminary Report [http://www.msf.or.jp/news/baseline/Baseline.pdf]...
... shows a ceiling effect inthe patient group, and the subtests have been shown tobe highly discriminatory between the normative group and the patients Further studies are required to ascertain the ... compare patients withthe normal population http://www.hqlo.com/content/4/1/18 writing of the manuscript AT and AE undertook the data analysis and interpretation, and also participated in writing the ... tothe pass score was made until DIF was found tobe absent Due tothe ceiling effect inthe normal population it was necessary to combine some of the subtests for the DIF analysis when comparing...
... from (indicating no pain) to 10 (indicating pain as bad as you can imagine) Higher scores indicate greater pain severity Based on previous analyses, scores of toare considered mild, toare considered ... moderate, and 15 to 21 are considered severe To assess pain intensity, subjects were asked to rate their average pain due to FM over the past 24 hours with an 11-point numeric rating scale ranging ... had tobe between 18 and 65 years of age and were excluded if they had participated in an investigational drug study within 30 days prior tothe survey or had a concomitant illness unrelated to...
... mutants was amplified using primers flanking the gene (5’-GCTCCGCAGTACGTCTTCTAAGCCC-3’ and 5’-GCGAGAATGGAACAATCAATGGACG-3’) and sequenced In addition tothe stop codon, e602 also contains a silent ... ventrally and instead project laterally along the body wall (arrow in (b)) Animals were stained with anti-serotonin antibodies to visualize the HSN neurons Arrowheads indicate the vulva Dotted lines ... using antibodies against GABA; and that of ALA and AVKR neurons using antibodies against FMRF-amide See Materials and methods for details n, number of animals scored terminated prematurely, and...
... Wales witha ratio of 1:4 [1] Table 1: Anatomical location of lymphomatous lymph nodes (n = 62) Anatomical location Number of cases Cervical Inguinal Axillary Intra-abdominal Supraclavicular Submandibular ... endoscopy and laparoscopy in obtaining biopsy material The advent of endoscopic ultrasound-guided FNAC allows targeting of mediastinal and intra-abdominal lymphadenopathy, which can be performed without ... lymphomas, one of the important roles of FNAC is the exclusion of metastatic squamous carcinoma as this requires an alternative therapeutic approach There is a question as tothe accuracy of FNAC in...
... Clinical reminders about required screenings and other tasks initially appear inthe EHR whena patient arrives inthe clinic and a nurse administers an initial screening Whenthe primary care ... implementation and the value added tothe organization by the EHR Participants’ recommendations may help healthcare administrators anticipate barriers to EHR implementation and work to address them, ... data analysis and drafted the manuscript CS conducted data analysis and helped to draft the manuscript LP participated in study design, data collection and analysis, and helped to draft the manuscript...
... drafting the manuscript and inthe review of the literature and in performing the clinical follow-up HG was involved in drafting the manuscript and inthe review of the literature SH participated ... the final draft Do you have a case to share? Submit your case report today • Rapid peer review • Fast publication • PubMed indexing • Inclusion in Cases Database Any patient, any case, can teach ... participated inthe surgery and was involved inthe clinical follow-up JR participated inthe surgery, was involved inthe clinical follow-up and supervised this report All authors read and approved the...
... Administration MedWatch database [10] described 151 complications associated with off-label use of FVIIa, the majority occurring in trauma patients However, MedWatch is a database for voluntary ... continues to hemorrhage Administration of FVIIa is certainly warranted in this patient Life-threatening hemorrhage and coagulopathy in critical care patients carries significant morbidity and mortality, ... mortality, with increased incidence of respiratory failure and renal failure as well as multiple organ dysfunction FVIIa has efficacy in restoring hemostasis Additionally, early administration — before...
... here can be easily accomodated for this case in changing the inequality sign in formula (7) and in taking an opposite argument for «1>(.) in (20) Threshold liability concept and beta binomial approaches ... especially more stable over parities as theoretically expected for such binary traits Using this value in (1 3a and b) leads to !o equal to -2.0242 and -1.8081, and h inthe binary scale to 0.0394 and ... progeny number n are rather less b pronounced These variations (An) in n are proportional to variations (A ) in ETA within the range of values considered For instance, for 7 = 0.75 uu An ?r -m...
... at the same time One of them will probably be used as the principal organizing, but the others are still there, even if they are not taken into accountinthe organization of the material Basing ... what is tobe learnt and why it is tobe learnt A syllabus provides a visible basis for testing, an inevitable part inthe process of language learning and teaching Beside its advantages above, ... as the route There are many constraints emerging on the route in designing syllabus Inthe study, both target and learning needs are taken into accountto determine the aims and objectives of the...
... changed dramatically inthe last two decades “Since the mid1980s there has been renewed interest inthe role of vocabulary in second language learning” (Coady and Huckin, 1997, p.ix) Being aware ... Baude, A Iglesias, M and Inesta, A (2004) to learn integrated English language skills: Listening, Speaking, Reading, and Writing However, Listening and Speaking arethe primary skills which are ... teaching vocabulary is how best to help students understand, retain and use words inthe target language So far, there have been many different approaches to vocabulary teaching and learning Chacón-Beltrán...
... Regional and County Estimates Remaining Uninsured in California under theA ordable Care Act: Regional and County Estimates Jacobs, Watson, Kominski, Roby, Graham-Squire, Kinane, Gans, and Needleman ... transitions are just some of the many ways the state and Exchange can maximize enrollment in health coverage in California Predicted Increase in Medi-Cal Enrollment under theA ordable Care Act: ... otherwise stated, estimates are for 2019 after employers and individuals have fully adjusted tothe changes in coverage availability and responsibilities under the ACA All estimates are for a...
... We assume a moderate increase inthe federal funds rate of about 130 basis points inthe next year Our estimates show that this will lead toa moderate increase in interest rates paid on U.S assets ... financial markets, with their associated legal guarantees and transparency, make the United States an attractive place for for- ting all their “eggs in one basket” (2004, p 2) This, coupled with ... mismeasured: measurement error has created “dark matter” that will keep global financial markets from running into a crisis They suggest that accounting conventions are inadequate and propose to...
... relevant data is not available to determine an average value and variability, the engineer may perform a sensitivity analysis using average parameters and a parameter reduced by one standard deviation, ... penetration to obtain the desired resistance is determined using the resistance factor for the static analysis method, equating the factored static analysis resistance tothe factored dynamic analysis ... concluding the analyses If, on the other hand, the Engineer determines that the calculation results are marginal or that the results are sensitive tothe selected parameter, additional data collection/review...