survival and growth of prostate cancer cells in the bone role of the alpha receptor for platelet derived growth factor in supporting early metastatic foci

Báo cáo khoa học: "Effects of propranolol in combination with radiation on apoptosis and survival of gastric cancer cells in vitro" ppsx

Ngày tải lên : 09/08/2014, 09:20

... treatment, the remaining intact cells were incubated at 37°C for 24 hr, and then the cells were washed with cold PBS at 4°C After centrifugation at 1500 rpm for min, 500 μL of 1×binding buffer, μL of ... Analysis of the data and plotting of the figures were performed with the aid of software (Origin Version 7.5 and SPSS Version 13.0) Results Expression of b1- and b2-adrenergic receptors in SGC7901 and ... radiotherapy led to a decrease in gastric cancer cell survival in vitro Adding the drug will enhance the sensitivity of gastric cancer cells to radiation through the inhibition of b-ARs and the...

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Báo cáo khoa học: "The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation" pot

Ngày tải lên : 09/08/2014, 09:20

... low levels of Bcl-2 in the PC3 cells may explain why the radiation-induced down-modulation of Bcl-2 was of minor importance for the response of PC3 -cells to radiotherapy and the combined treatment ... down-regulation of p-Akt may be required for the anti-neoplastic action of small molecule inhibitors of the PI3K/Akt pathway in prostate cancer cells Combined effects of ErPC3 and ionizing radiation in prostate ... alkylphosphocholine perifosine in different solid tumor cells in vitro including lung and prostate cancer [12,14,17,25,26] Altogether, these observations suggest a role of Akt-inhibition for the cytotoxic...

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Báo cáo khoa học: "In vitro studies on the modification of low-dose hyper-radiosensitivity in prostate cancer cells by incubation with genistein and estradiol" pot

Ngày tải lên : 09/08/2014, 09:22

... study were the use of FCS-containing media during genistein incubation and the incubation with higher genistein doses Mechanisms of interaction To search for mechanisms of interaction we investigated ... (figure 1) In contrast, in our passages of PC-3 cells we could not stain any of these receptors Genistein inhibits clonogenic cell survival in LNCaP and PC-3 In PC-3 cells we tested genistein concentrations ... brown staining For easier analysis, staining of the nuclei with DAB was not performed in the presented samples of LNCaP and PC-3 While LNCaP cells showed expression of ER-α and ER-β, PC-3 cells...

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Báo cáo khoa học: " No supra-additive effects of goserelin and radiotherapy on clonogenic survival of prostate carcinoma cells in vitro" ppsx

Ngày tải lên : 09/08/2014, 10:21

... seem to explain the clinically observed increase of overall survival in patients after combined therapy Recent studies investigated the effects of AD and radiotherapy in PC cell lines in vitro [summarized ... incubation and irradiation induced the expression of phosphorylated ERK1/2 in LNCaP cells In PC-3, only the combination of irradiation and goserelin increased the level of phosphorylated ERK1/2 These ... diluted 1:20 in PBSTN; the cells were incubated therein at 4°C overnight After three washes in PBST, the cells were incubated with PBSTN for 30 and then treated with the Histostain SP kit for mouse...

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báo cáo khoa học: " XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells" docx

Ngày tải lên : 10/08/2014, 10:20

... somatostatin indicates a promising strategy for prostate cancer therapy Materials and methods Cell lines and cell culture A human prostate epithelial cell line (RWPE-1) and prostate cancer cell lines ... mRNA and protein by somatostatin and Octreotide in prostate cancer cell lines To examine the regulatory effects of somatostatin and Octreotide on XAF1 mRNA and protein expression, prostate cancer ... mimic the development of prostate cancer clinically Understanding the regulating effects of XAF1 during the whole progression may help us find potential therapeutic strategies for prostate cancer...

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A role for chondroitin sulfate proteoglycan in regulating the survival and growth of neural stem cells

Ngày tải lên : 12/09/2015, 21:26

... chorion (the embryonic portion of the placenta), while the inner cells generate the inner cell mass (ICM) and form the embryo proper including the yolk sac and amnion The trophectoderm and the ICM ... been standardized and many factors including the source of stem cells and the environment into which they are placed will be important in determining the outcome In humans, transplantation of foetal ... rise to the digestive tube and its associated organs including the lungs The ectodermal layer on the outside forms the skin, nerves and pigment cells The mesoderm is in between and forms the blood,...

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Báo cáo khoa học: Altered expression of tumor protein D52 regulates apoptosis and migration of prostate cancer cells potx

Ngày tải lên : 30/03/2014, 02:20

... tissue, survival and proliferation in the host tissue [31] The expression of several genes, such as CARD10 [32] and Vav3 [33], and integrins is important in determining the formation of metastatic cells ... cells [34,35] The expression of murine TPD52 in NIH3T3 cells induces the expression of several genes involved in the promotion of metastasis and the genes responsible for prevention of metastasis ... a role in the development of the epithelial cell phenotype [13] Its expression is controlled by androgens in LNCaP cells [9] The major circulating androgen, testosterone, interacts with the androgen...

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costs and effectiveness of prostate cancer screening in elderly men potx

Ngày tải lên : 01/04/2014, 13:20

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báo cáo hóa học:" High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis" potx

Ngày tải lên : 18/06/2014, 15:20

... effect on the growth and metastasis of cancer cells in the group to which ascorbic acid had been injected before injecting cancer cells into the abdominal cavity Past research on the anticancer ... the beginning of the experiment Group D showed a survival rate of 0% after 25 days, and Group E showed a survival rate of 0% after 28 days from the beginning of the treatment In contrast, F and ... (hypoxia-inducible factor- 1 alpha) is involved in tumor growth as a vector to which cells adapt in hypoxia, and is also involved in cancer metastasis by increasing the expression of other angiogenesis...

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Báo cáo sinh học: " Downregulation of APOBEC3G by Xenotropic Murine Leukemia-Virus Related Virus (XMRV) in Prostate Cancer Cells docx

Ngày tải lên : 18/06/2014, 18:20

... levels of A3G protein XMRV is able to productively replicate in these cells Findings This report builds on and challenges the published data on the absence of A3G protein in prostate epithelial cells ... day before infection Cells were at 50% confluency at the time of infection On the day of infection, fresh media containing µg/ml polybrene was added to the cells and virus was layered on the cells ... cells have the ability to productively infect and replicate in target cells Therefore our findings challenge the notion that the prostate epithelial cell lines were able to produce infectious...

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Báo cáo khoa học nông nghiệp " Effects of Stocking Biomass on Growth, Survival and Production of the Two Sizes of Clam Meretrix lyrata Cultured in the Intertidal Areas And Notes on Hatchery Production of Clam Spat " pot

Ngày tải lên : 21/06/2014, 05:20

... due the fact that the increase in biomass negatively affected the growth and survival of the clams In the bigger stocking size (1.7 cm), the final production of the clam was significant increased ... objective of this research was to evaluate the effect of stocking biomass of the two sizes of M lyrata on growth performance and survival to enhance the production and profit of cultivation The other ... survival rate The biomass gained therefore was reduced accordingly with increasing of stocking biomass although the increase of final production was evident However, SGR and survival of the treatments...

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Báo cáo nghiên cứu khoa học " CLAM CULTURE DEVELOPMENT IN THE INTERTIDAL AREA: EFFECTS OF STOCKING BIOMASS ON GROWTH, SURVIVAL AND PRODUCTION OF THE TWO SIZES CLAM Meretrix lyrata " docx

Ngày tải lên : 22/06/2014, 12:20

... to the fact that the increase in biomass negatively affected the growth and survival of the clams In the bigger stocking size (1.7 cm), the final production of the clam was significantly increased ... The estimation of the economic benefit of clam cultured in the intertidal areas is showed in table The net profit is calculated based on the output cost and input cost and price of the clam The ... growth and production The objective of this research was to evaluate the effect of stocking biomass of the two sizes of M lyrata on growth performance and survival to enhance the production and...

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Báo cáo lâm nghiệp: " Survival and growth of Pinus halepensis Miller seedlings in a semi-arid environment after forest soil transfer, terracing and organic amendments" docx

Ngày tải lên : 08/08/2014, 18:21

... treatments and in a single application at the beginning of the experiment in October 1992 The dose used was 10 kg m in both mechanical and ma-2 nual terraces was experiment, Growth data of the seedlings ... Differences in fertility may explain the observed improvement in P halepensis growth with added USR, but they not explain the better growth of the pines in the mechanical terraces compared to that in the ... amendment was incorporated into the top 30 cm of the whole terrace using a rotovator In the manual terraces, the refuse was only incorporated into the planting holes using a shovel In November...

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Báo cáo y học: "An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue" pot

Ngày tải lên : 09/08/2014, 01:22

... immunofluorescence and 3,3-diaminobenzidine disclosure) for aggrecan and the staining intensity increased with time post injection (Figures and 5b) Aggrecan matrix staining within the vicinity of ... performed the type X collagen and Alizarin red staining, and participated in interpretation of the data AJF participated in interpretation of the data and contributed to the preparation of the ... within a small number of cells in monolayer culture Following injection into NP tissue explants, MSCs stained strongly positive for type II collagen and matrix staining in the vicinity of the injected...

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Báo cáo khoa học: "The alkylphospholipid, perifosine, radiosensitizes prostate cancer cells both in vitro and in vivo" docx

Ngày tải lên : 09/08/2014, 09:20

... Radiosensitization of perifosine in prostate cancer PC-3 cells Cells were irradiated in the absence (control) or in the presence of perifosine and the colony formation assay was conducted Shown are the means and ... are the means and standard deviation of each individual treatment points B, Cells were irradiated in the absence (control) or in the presence of 15 μM and 30 μM perifosine and the colony formation ... alkylphospholipids, including perifosine, are attractive candidates for combination treatment with radiotherapy The aim of this study was to investigate the effect of the combined treatment of perifosine and...

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báo cáo khoa học: "Inhibition of angiogenesis- and inflammation-inducing factors in human colon cancer cells in vitro and in ovo by free and nanoparticle-encapsulated redox dye, DCPIP" pptx

Ngày tải lên : 11/08/2014, 00:22

... μg/ml of DCPIP and DCPIP NPs The GI50, i.e the concentration that inhibits the growth of 50% of the cells, and LC50, i.e the lethal concentration that kills 50% of the cells, were determined to ... angiogenesis in gastric cancer [13], and acquisition of chemotherapeutic resistance in androgenindependent proliferation of prostate cancer cells [14] Finally, there is extensive experimental and clinical ... to indicate that the nuclear transcription factor- κB (NF-κB) is activated during, and therefore links, the processes of angiogenesis, inflammation and carcinogenesis [21-24] Therefore, we investigated...

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EFFECTS OF CHOLINE KINASE ACTIVITY ON PHOSPHOLIPID METABOLISM AND MALIGNANT PHENOTYPE OF PROSTATE CANCER CELLS

Ngày tải lên : 24/08/2014, 10:38

... of choline kinase isoforms Alignment of human choline kinase isoforms (hCKα2, α1, β2), C elegans choline kinase isoform alpha- 2 (cCKA2), mouse choline kinase isoform alpha- 1 and beta (mCKα1 and ... Log10 of (mRNA signal in tumoral cells/ mRNA signal in HMEC) ChKα represents both choline kinase alpha1 and alpha2 while ChKβ represents choline kinase beta isoform Comparison of the isoforms of ... in kidney and liver In future, identification, cloning and characterization of choline transporters in cancer cells will lead to better understanding of their role in carcinogenesis 3.3 Choline...

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Báo cáo y học: "High-Resolution Flow Cytometry: a Suitable Tool for Monitoring Aneuploid Prostate Cancer Cells after TMZ and TMZ-BioShuttle Treatment"

Ngày tải lên : 26/10/2012, 09:48

... ratio of 25 % diploid and 24 % aneuploid cells in the TMZ probe G1-phase: The comparison of the amount of aneuploid and diploid cells in the G1 phase shows a ratio of 49 % and 54% The cells in the ... arrest of diploid cells in the G1 phase, whereas the cells of the aneuploid fraction pass from the G1 into the S phase This finding is confirmed by the investigation of DU 145 cells in the S phase: ... dienophile compound in the DARinv It is connected via the ε-amino-coupling of the lysine spacer to the nuclear address sequence (NLS) At the right site of the table the CPP module in the single letter...

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Báo cáo y học: "Why are some children with early onset of asthma getting better over the years" -aneuploid-prostate-cancer-cells-after-tmz-tmz-bioshuttle-treatment.html#post143974

Ngày tải lên : 26/10/2012, 09:48

... Hospital, including PHC data of the statements made by the mid-wife in her records of the check-up of the mothers during the pregnancy (17) In the follow-up at the age of seven, n= 191 children of the ... those suffering neonatal death and those living outside the region, were included in the study At the age of seven, all of them still living in the region were included in a follow-up of their computerised ... on the role of infection in the education of the immune system of young children, can not solely explain the trends in asthma prevalence or account for potential environmental influences on the...

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