size brain edema or cerebrospinal fluid glutamate concentrations in rats following controlled cortical impact pdf
báo cáo hóa học:" Variables that influence HIV-1 cerebrospinal fluid viral load in cryptococcal meningitis: a linear regression analysis" pot
... stimulation in the cerebrospinal fluid during HIV infection: a longitudinal study Scand J Infect Dis 1994, 26:523-33 Price RW, Staprans S: Measuring the "viral load" in cerebrospinal fluid human ... this organism (or its antigens) could directly enhance viral replication in addition to promoting an inflammatory response in the CNS However, in the clinical setting of our investigation, no correlation ... cellular events in brain parenchyma Therefore, investigations of HIV-1 have used CSF as a surrogate for brain pathophysiologyc events [5,6] HIV-1 is found in the CSF of most infected individuals...
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báo cáo khoa học: " Gingival crevicular fluid MMP-8-concentrations in patients after acute myocardial infarction" pdf
... enzymes in gingival crevicular fluid as diagnostic indicators of periodontitis J Clin Periodont 1994, 21:497-506 10 Sorsa T, Tjäderhane L, Salo T: Matrix metalloproteinases (MMPs) in oral diseases Oral ... disease including gingivitis, bone loss and missing teeth is an independent but relatively weak risk factor for CHD Individuals suffering from periodontal disease have approximately a 24-35% increased ... study, and participated in its design and coordination All authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests Received: 12...
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Báo cáo y học: "Minocycline fails to modulate cerebrospinal fluid HIV infection or immune activation in chronic untreated HIV-1 infection: results of a pilot stud" doc
... important for macrophages in sustaining infection and also, perhaps, in their entry into the CNS, including into the perivascular spaces, meninges and parenchyma Minocycline might, therefore, ... load” in cerebrospinal fluid in human immunodeficiency virus infection: window into brain infection? Ann Neurol 1997, 42(5):675-678 37 Price RW: The two faces of HIV infection of cerebrospinal fluid ... and memory phenotypes in cerebrospinal fluid during HIV infection J Acquir Immune Defic Syndr 2005, 39(1):16-22 43 Tikka T, Fiebich BL, Goldsteins G, Keinanen R, Koistinaho J: Minocycline, a...
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Báo cáo y học: "Herpes simplex 1 encephalitis presenting as a brain haemorrhage with normal cerebrospinal fluid analysis: a case report" pot
... Differences in laboratory findings for cerebrospinal fluid specimens obtained from patients with meningitis or encephalitis due to herpes simplex virus (HSV) documented by detection of HSV DNA Clin Infect ... had temporal abnormalities more commonly hyperintensity lesions in the T2weighted images in one or both inferomedial regions of the temporal lobes, which usually extended to the insular cortex ... autopsy or a brain biopsy were necessary Enrolment in clinical trials of treatment for HSVE sponsored by the Collaborative Antiviral Study Group of the National Institute of Allergy and Infectious...
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Báo cáo hóa học: " Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats" pptx
... after IS induction, n = 15) Five rats in groups and were utilized for determining the brain infarct size The sensorimotor functional test (Corner test) was performed by blinded investigators for each ... by saline injection alone Accordingly, rather than supporting a crucial role of direct cellular participation in limiting brain infarct size and improving neurological function, our findings suggest ... day 21 following acute IS induction, mRNA expressions (Figure 3) of interleukin-18 (IL-18), toll-like receptor (TLR)-4, and plasminogen activator inhibitor (PAI)-1 in BIA, indexes of inflammation,...
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Báo cáo sinh học: "Combination of cyclosporine and erythropoietin improves brain infarct size and neurological function in rats after ischemic stroke" potx
... snap-frozen in liquid nitrogen before being stored at -80°C For immunohistochemical (IHC) staining, the brain tissue was fixed in 4% formaldehyde and embedded in paraffin Additionally, the brain tissue ... reduced in group than in other groups Additional important finding also includes the remarkably increased number of GFAP-positive cells, an indicator of inflammatory cells in ischemic brain, in group ... administration of cyclosporine limits infarct size, attenuates remodeling and preserves left ventricular function in porcine acute anterior infarction Int J Cardiol 2011, 147:79-87 Leu S, Lin YC, Yuen CM,...
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báo cáo hóa học: " Soluble HLA measurement in saliva and cerebrospinal fluid in Caucasian patients with multiple sclerosis: a preliminary study" pdf
... HLA-II levels, in MS has been reported [14] Fainardi et al [15] reported a decrease in sHLA-I concentrations during exacerbations in MS, but an increase in CSF sHLA-I was observed in patients with ... technique after the informed consent was reviewed with the patient and signed Brain MRI was performed using a 1.5 T machine with a standard quadrature head coil The imaging protocol included sagittal ... http://www.jneuroinflammation.com/content/2/1/13 Demonstration of the distribution curves for soluble HLA-II levels in the cerebrospinal fluid (unbroken line) and saliva (dotted Figure line) in multiple...
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báo cáo hóa học: " Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats" pdf
... changing the intracellular content of this protein LPS induces increases in S100B levels in cerebrospinal fluid, but not in serum Anesthetized adult rats received 10 μL ICV of 2.5 μg/μL LPS or ... 0.001) In order to characterize whether the effect of Figure LPS induces increased levels of S100B in cerebrospinal fluid (CSF), but not in serum Intracerebroventricular injection of LPS, or saline ... cerebrospinal fluid and serum changes of this protein in neuroinflammatory diseases and brain disorders in general Moreover, S100B-expressing tissues may be differentially regulated, since LPS...
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báo cáo hóa học: " Lateral fluid percussion injury of the brain induces CCL20 inflammatory chemokine expression in rats" pdf
... washed in PBS, incubated in avidinbiotin complex mixture (ABC,1:100; Vector Laboratories Inc, Burlingame, Ca) for h, washed again and visualized using DAB/peroxide solution (Vector Laboratories Inc) ... traumatic brain injury [34] Furthermore, a recent study identified CCL20 as a dual-acting chemokine with the potential for inhibiting immune reactions and more importantly in attracting inflammatory ... that LFPI-induced brain Page 15 of 16 injury evoked an inflammatory reaction in the injured brain and attracted a population of activated microglia resulting in further damage of the brain The fact...
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Báo cáo khoa học: "Glutamate and GABA concentrations in the cerebellum of novel ataxic mutant Pogo mice" pdf
... mice In H Flohr, Post-lesion Neural Plasticity, pp 431-442, Springer, Berlin/Heidelberg 1988 15 Hawkins, R A., DeJosepf, M R and Hawkins, P A Regional brain glutamate transport in rats at normal ... (Dakopatts Inc., Mississauga, Canada) for hours at room temperature After three additional rinses in TPBS, antibody-binding sites were revealed by a 15 incubation in 0.2% diaminobenzidine in TPBS ... great increase in glutamate level during the pre-convulsive state, and the seizures themselves were blocked by AP5 given intraventricularly 30 mins before seizure induction, in which GABA levels increased...
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Báo cáo y học: "Plasmatic B-Type Natriuretic Peptide and C-Reactive Protein in Hyperacute Stroke as Markers of Ct-Evidence of Brain Edema." pptx
... of treatment in stroke-induced brain edema remains to be elucidated The lack of efficacious treatment so far for stroke-induced brain edema makes our hypothesis Int J Med Sci 2008, worthy of consideration ... of brain edema in stroke at baseline and after 48 hours respectively Given that brain edema may be a life-threatening condition, anti -edema measures could be anticipated in hyperacute stroke in ... subarachnoid hemorrhage [28] In rodent model of subarachnoid hemorrhage the intraventricular administration of ANP reduced the sodium and water accumulation, as well as brain edema [29] In rats with...
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Báo cáo y học: "Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus" ppsx
... without MRI-verified brain pathology This finding, together with increased intrathecal levels of TGF-β, indicates an ongoing destructive parenchymatous process in the SLE brain In addition, the present ... biochemical indices are indirect measures of brain inflammation In contrast to a multitude of studies analyzing local inflammatory response in NPSLE, the evaluation of neuronal damage and the formation ... confirmatory diagnostic test available Several clinical, laboratory, and radiographic test findings are reported to be abnormal in some but not all patients with CNS lupus Magnetic resonance imaging...
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Báo cáo y học: "Association of cerebrospinal fluid anti-ribosomal P protein antibodies with diffuse psychiatric/neuropsychological syndromes in systemic lupus erythematosus" pps
... Figure lacking the C-terminal 22-amino recombinant ribosomal P0 protein Cerebrospinal fluid antibodies toacid sequence lacking the C-terminal 22-amino acid sequence Antibodies to recombinant ribosomal ... (anti-PEX.C22), and to recombinant ribosomal P0 protein lacking the C-terminal 22amino acid sequence (anti-C22-depleted rP0) in cerebrospinal fluid from patients with non-inflammatory neurological diseases ... using a standard serum Non-specific binding activities to HSA for anti-PC22 or those to wells with PBS alone or coating buffer alone for anti-whole P or anti-C22-depleted rP0 were also determined...
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Báo cáo y học: "Cerebrospinal fluid signs of neuronal damage after antiretroviral treatment interruption in HIV-1 infectio" docx
... thereby indicating brain injury in this setting The mechanisms responsible for this rise in NFL remain to be determined Indeed, from a virological perspective, it is uncertain whether the increase in ... application of cerebrospinal fluid neopterin concentrations in HIV infection Pteridines 2004, 15:102-106 Tibbling G, Link H, Öhman S: Principles of albumin and IgG analyses in neurological disorders ... course of changes in salient laboratory findings in the eight subjects (A-H) Time course of changes in salient laboratory findings in the eight subjects (A-H) Sets of three graphs for each subject...
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Báo cáo y học: "Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection" ppt
... as cyclosporin-A, and Th2-type cytokines including interleukin-4 and -10 counteract the production of neopterin [21] The same is true for anti-inflammatory compounds including certain HMG-CoA ... 5,6,7,8-Tetrahydrobiopterin (BH4) Neurons Dephosphorylation Oxidation (e.g., HOCl) Neopterin Macrophage lineage Figure Induction of neopterin formation in brain cells Pro-inflammatory cytokines like interferon-γ ... interest in the future to examine whether neopterin or other CSF immune inflammatory markers might help to understand and clinically distinguish and monitor this disorder [38] CSF Neopterin in...
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báo cáo khoa học: "Hepatic cerebrospinal fluid pseudocyst mimicking hydatid liver disease: a case report" doc
... of the cystic fluid increases, interstitial fluid passes into the cyst, and the cyst increases in size [2] Hydatid disease is endemic in the Middle East The combination of imaging and serology ... resolved, shunt revision following cyst aspiration; or draining the cyst fluid through a explorative laparotomy, unroofing the cyst wall, then shunt revision or repositioning In recent years, laparoscopic ... showing continuity with hepatic tissue [13] The standard treatment of a hepatic pseudocyst secondary to catheter tip migration, in cases with no infection or prominent inflammatory reaction in...
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Báo cáo y học: "Minocycline-induced hypersensitivity syndrome presenting with meningitis and brain edema: a case report'''' doc
... symptoms at discharged form care Discussion Minocycline is widely prescribed for acne vulgaris [4] Minor adverse effects including nausea, vomiting, dizziness, photosensitivity and skin eruption have ... lymphocytic meningitis and cerebral edema have not been described in association with minocycline-induced HS, they have been reported following use of allopurinol [9] Page of (page number not for citation ... and definitively withdrawn for the patient If used, minocycline should be strictly monitored, especially in African or HIV-infected patients Jacques Margery for his help in the publishing process...
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Báo cáo y học: " Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report" pptx
... negative intrathoracic pressure, created during inspiration, coupled with increased hydrostatic intra-abdominal pressure [2] In addition to causing a build-up of ascitic fluid, sub-clinical inflammation ... Furthermore, as demonstrated in a previous case report, CSF ascites can occur despite normal levels of protein in the CSF [10] The finding of CSF ascites in our patient can be used to explain the coincident ... Congenital diaphragmatic defects or weak points in the diaphragm such as the Foramen of Morgagni or Foramen of Bochdalek provide potential conduits Furthermore, one or more microscopic diaphragmatic...
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Báo cáo khoa học: "Cortisol levels in cerebrospinal fluid correlate with severity and bacterial origin of meningitis" pot
... procalcitonin) or cerebrospinal fluid (CSF; for instance, protein, glucose, WBC, lactate, inflammatory cytokines and combinations thereof) has been suggested to improve sensitivity in determining the ... meningitis Moreover, CSF cortisol may help to discriminate bacterial meningitis from aseptic meningitis reliably Finally, our findings support the pathophysiological importance of intrathecal cortisol ... During critical illness, cortisol-binding globulin and albumin blood levels decrease by about 50%, leading to an increase in biologically active free cortisol It is likely that the increase in...
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