... ).
The renewed interest in examining the indications for BCG vaccination in the
United States included consideration ofthe wide range of vaccine efficacies deter-
mined by clinical trials and ... to
explore the sources ofthe heterogeneity inthe efficacy ofthe BCG vaccine reported in
the individual studies. Using a model that included the geographic latitude of the
study site andthe data ... resurgence inthe incidence of TB occurred inthe United
States and included increases inthe number of TB cases among adults and children
and outbreaks of multidrug-resistant TB (MDR-TB) involving...
... a
role in managing chest pain from the point of entry, they
must acquire and demonstrate competence in diagnosing
the complaint.
Chest pain can have a multitude of etiologies, involves an
inherently ... set of themes as reached via consensus.
This process involved examining themes for commonal-
ity, classifying them for uniformity, and then reaching
agreement on the final list of six key themes. ... for
chest pain will depend on the nature ofthe condition and
the urgency ofthe situation, that the point of referral may
depend on the familiarity or relationship between the
providers, and that the...
... Framework
Conclusions, including the results
of the November 2001 Workshop
Management Framework - Introd
uced Marine Pests
Management capabilities
and approaches
APEC andthe MRCWG have a rolein liaising ... Pests
Background
Within APEC little is known on the
introduction of marine pests
Little practical information on
measures to prevent introductions
Lack of knowledge in what
individual countries are doing
Need ... NACA to enhance the
effectiveness of existing instruments within
APEC
Institutional arrangements for managing the
marine environment is fragmented in most
economies
Baseline surveys to...
... long way in influencing the target market and marketing approach to drive the
demand of organics. The second LDF 2 identified the person responsible for shopping andthe
location ofthe consumer ... with information that has established
the decline of agriculture generally inthe province. Inthe Ciskei, the second most
preferred shopping place is the Grocery stores mentioned by 23.1% ofthe ... regression andthe
standardized discriminant functions to analyze the resulting data. There is evidence of
growing interest in organic products inthe province, with a sizeable proportion of
respondents...
... points ofthe 11 basis-point decline
in the average expense ratio of funds of funds over the period
(labeled in Figure 13 as “Fall in expense ratios of individual
funds”). By definition, the ... inflation by taking the fee breakpoints available in 2010 and multiplying by the Consumer Price Index
in December 2000 and dividing by the Consumer Price Index in December 2010.
3
The front-end ...
Trends inthe Fees and Expenses of Mutual
Funds, 2010
KEY FINDINGS
»
On average, fees and expenses incurred by investors in long-term mutual funds
declined in 2010. Stock fund investors in 2010...
... percentage
of the assets that the financial professional manages
for an investor, rather than as a percent ofthe dollars
initially invested. Over time, brokers and other financial
professionals ... underlying funds in
which it invests. Since 2005, the average expense ratio for investing in funds of funds
has fallen 18 basis points.
»
The average expense ratio investors paid to hold either index ... including
its investment objective, its level of assets, the average
account balance of its investors, the range of services it
offers, fees that investors may pay directly, and whether
the...
... the majority of rain during the
Southwest monsoon. Generally, the quantity of rainfall decreases with increasing distance
from the sea, but the amount of rainfall andthe length of rainy season ... plantation were interviewed in Thai with the help of a translator. The
basic information of planted clone, area of plantation and age ofthe trees was obtained in this
way. In addition, information ... Research
Institute of Thailand (RRIT) andthe Office ofthe Rubber Replanting Aid Fund (ORRAF).
The RRIT works under the Department of Agriculture (Ministry of Agriculture and
Cooperatives), and its...
... asylum inthe UK has become increasingly
controversial and emotive, successive governments have focused on reducing the number of
asylum applications inthe UK and on increasing the number of asylum ... another and to make sure that they did not imbue
the responses of interviewees with their own meaning and terminology. In some cases the
interpreters had previously worked with the clients and ... though the
resultant frameworks developed for charting and interpreting data were compared. Codes
and frameworks were rooted inthe aims ofthe project and guided by the nature ofthe
interview...
... state
(disordered inthe ligand-free state in YbgJ). In the
absence ofthe ligand, the lid part is separated from
the active site, which leads to a more open active site.
Upon the binding of ligand inthe ... sites of Mglu and Bacillus glutaminase inthe presence and absence of ligands. Backbone atoms ofthe seven conserved
amino acid residues andthe three conserved tyrosine residues in Mglu and Bacillus ... conformations ofthe regions at
100-105 and 303-309 aa inthe N form, and we investi-
gated the following points. First, these areas are not
involved in any contacts with other molecules in crys-
tals...
... once into the idea ofthe children in regard to them, and treated them always as if they
were real persons; often speaking of them and to them, inthe presence ofthe other children, inthe most
serious ... all in his power to make the yoke of obedience light and easily to be
borne.
Influence on the healthful Development ofthe Brain.
Indeed, besides the bearing of these views on the happiness ofthe ... for them to come simply because their mother
CHAPTER IV. 20
commands and signals, without being trained. In all these cases they perceive the necessity of training and
instruction, and understand...
... Ponting CP (1998) Evidence that the
conformation of unliganded human plasminogen is
maintained via an intramolecular interaction between
the lysine-binding site of kringle 5 andthe N-terminal
peptide. ... effective in
elevating Glu-plasminogen–fibrin binding. The actions
of complestatin are canceled by a lysine analog. Thus,
the target of complestatin is Glu-plasminogen, and the
agent promotes its binding ... The surfactin C
action involves modulation of Glu-plasminogen activa-
tion through relaxing the conformation ofthe protein.
Surfactin C increases the intrinsic fluorescence of
Glu-plasminogen, shortens...
... Ca
2+
.
Removing the proposed Ca
2+
-coordinating residues in
positions 1 and 3 ofthe EF-hand motif significantly
compromised the metal-binding capability ofthe engi-
neered protein, indicating that the ... demonstrate
that the conformation of CD2 is unchanged. After the
insertion ofthe helix–loop–helix EF-hand domain
from STIM1, the helical content ofthe engineered
protein CD2.STIM1.EF increased, indicating ... grafting approach to address this
question. As shown in Fig. 1B, the distance between
the two termini ofthe inserted Ca
2+
-binding sites in
the model structure ofthe EF-hand of STIM1 is within
15...
... represents an intermediate in processing.
These findings indicate that the processing of pro-CPA
occurs in (at least) two steps, and that the processing
of the intermediate form of CPA to mature ... Both the kinetics of
accumulation andthe level of maximal storage were
virtually identical in SG
+ ⁄ +
and SG
– ⁄ –
cells, indica-
ting that the storage of b-hexosaminidase is independ-
ent of ... on serglycin. Together,
these findings indicate that the reduced amounts of neutral proteases in the
absence of serglycin is not caused by missorting into the constitutive path-
way of secretion,...