promoter precore and core regions of hepatitis b virus and their clinical signifi cance
Báo cáo khoa học: " The role of mutations in core protein of hepatitis B virus in liver fibrosis" pdf
... C-terminal of < /b> the core < /b> protein as well as in B cell, T helper and < /b> CTL epitopes of < /b> HBV core < /b> gene sequence and < /b> the effects of < /b> these mutations on the clinical, biochemical and < /b> virological parameters of < /b> ... maturation stage of < /b> the HBV has To explain the effect of < /b> mutations of < /b> core < /b> protein in the biological process of < /b> the cell, we predicted the major functions of < /b> the core < /b> protein of < /b> hepatitis < /b> B virus Protein ... C-terminal domain and < /b> CTL epitopes of < /b> core < /b> protein were associated with more severe liver fibrosis Abbreviations used in this paper (HBV): Hepatitis < /b> B virus; (CHB): Chronic hepatitis < /b> B; (CTL): Cytotoxic...
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Báo cáo y học: "Epidemiology and Prevention of Hepatitis B Virus Infection"
... Quantitative analysis of < /b> HBV DNA level and < /b> HBeAg titer in hepatitis < /b> B surface antigen positive mothers and < /b> their babies: HBeAg passage through the placenta and < /b> the rate of < /b> decay in babies J Med Virol ... B e antigen-negative chronic hepatitis < /b> B in Hong Kong Hepatology 2000;31:763-768 49 Yoo BC, Park JW, Kim HJ, Lee DH, Cha YJ, Park SM Precore < /b> and < /b> core < /b> promoter < /b> mutations of < /b> hepatitis < /b> B virus and < /b> ... consecutive HBeAg-negative patients, 17.7% of < /b> HBeAg-negative patients had e-CHB [49] Most patients with e-CHB harbor HBV variants in the precore < /b> or core < /b> promoter < /b> region The most common precore < /b> mutation,...
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Báo cáo y học: "Natural History and Clinical Consequences of Hepatitis B Virus Infection"
... establishes, the serology markers like HBeAg, HBeAb and < /b> HBsAb can be positive or negative except HBsAg and < /b> HBcAb (IgG form) remain positive HBeAg positive chronic hepatitis < /b> B Age at the time of < /b> ... majority of < /b> patients remain HBeAg negative with positive HBeAb and < /b> their clinical presentation can be HBeAg negative chornic hepatitis < /b> B, but some patients may have seroreversion of < /b> HBeAg and < /b> present ... Genotypes and < /b> clinical phenotypes of < /b> hepatitis < /b> B virus in patients with chronic hepatitis < /b> B virus infection J Clin Microbiol 2002;40:1207-1209 McMahon BJ, Holck P, Bulkow L, et al Serologic and < /b> clinical...
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Báo cáo sinh học: " Cellular apoptosis induced by replication of hepatitis B virus: possible link between viral genotype and clinical outcome" pptx
... analysis of < /b> apoptotic effect by HBV genome A, B, and < /b> C Flow cytometry analysis of < /b> apoptotic effect by HBV genome A, B, and < /b> C HepG2 cells were transiently transfected with HBV genome A, B, and < /b> C and < /b> ... as BHRF1 of < /b> EBV and < /b> E 1B1 9k of < /b> Adenovirus [19,20] On the other hand, viruses also developed proapoptotic mechanisms in the late stage of < /b> infection to break host cell and < /b> promote the spread of < /b> ... characterization of < /b> hepatitis < /b> B virus surface antigen mutants in Singapore patients with hepatocellular carcinoma and < /b> hepatitis < /b> B virus carriers negative for HBsAg but positive for anti-HBs and < /b> anti-HBc J...
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Báo cáo hóa học: " Cellular apoptosis induced by replication of hepatitis B virus: possible link between viral genotype and clinical outcome" docx
... analysis of < /b> apoptotic effect by HBV genome A, B, and < /b> C Flow cytometry analysis of < /b> apoptotic effect by HBV genome A, B, and < /b> C HepG2 cells were transiently transfected with HBV genome A, B, and < /b> C and < /b> ... as BHRF1 of < /b> EBV and < /b> E 1B1 9k of < /b> Adenovirus [19,20] On the other hand, viruses also developed proapoptotic mechanisms in the late stage of < /b> infection to break host cell and < /b> promote the spread of < /b> ... characterization of < /b> hepatitis < /b> B virus surface antigen mutants in Singapore patients with hepatocellular carcinoma and < /b> hepatitis < /b> B virus carriers negative for HBsAg but positive for anti-HBs and < /b> anti-HBc J...
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Báo cáo khoa học: " Seroprevalence of Hepatitis B virus and Hepatitis C virus among blood donors in Nyala, South Dar Fur, Sudan" ppsx
... Gao ZL: High level of < /b> hepatitis < /b> B virus DNA after HBeAg-to-anti-HBe seroconversion is related to coexistence of < /b> mutations in its precore < /b> and < /b> basal core < /b> promoter < /b> World Journal of < /b> Gastroenterology ... Hospital blood bank as a preliminary screening test and < /b> thereby the risk of < /b> transfusing infected blood and < /b> establishment of < /b> new foci of < /b> infection exist In this study liver damage assessment of < /b> the ... anti-HCV antibodies, negative samples reasonably well, but, because of < /b> their short incubation times the assays not always identify low affinity/low concentration of < /b> antibodies Page of < /b> (page number not...
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Báo cáo y học: " Seropositivity of Hepatitis B virus and Hepatitis C virus dual Infection among blood donors in Nyala Teaching Hospital" pot
... the clinical and < /b> virological characteristics among patients with single occult hepatitis < /b> B virus (HBV), single occult hepatitis < /b> C virus (HCV) and < /b> occult HBV and < /b> HCV dual infection Journal of < /b> Medical ... Alberti A, Ruol A: Hepatitis < /b> C virus infection in chronic hepatitis < /b> B virus carriers Journal of < /b> Infectious Diseases 1991, 163:400-402 Abou MA, Eltahir YM, Ali AS: Seroprevalence of < /b> Hepatitis < /b> B ... of < /b> both viruses in South Dar Fur State, Sudan, in which the seroprevalence of < /b> HBV is of < /b> an intermediate level (6.25%) and < /b> HCV seroprevalence of < /b> low level (0.65%)[14] Dual infection of < /b> HBV and...
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COMPUTATIONAL CHARACTERIZATION FOR GENOME INTEGRATION SITES OF HEPATITIS b VIRUS (HBV) AND GENE TARGETS OF HBV x PROTEIN
... INTEGRATION SITES OF < /b> HEPATITIS < /b> B VIRUS (HBV) AND < /b> GENE TARGETS OF < /b> HBV X PROTEIN LIU LIZHEN (B. Sc (Hons.), NUS) A THESIS SUBMITTED FOR THE DEGREE OF < /b> MASTER OF < /b> SCIENCE DEPARTMENT OF < /b> BIOCHEMISTRY YONG ... patients, and < /b> the clinical data of < /b> the 100 HCC patients A total of < /b> 2860 potential HBx binding sites were identified and < /b> were found to be significantly enriched in exons and < /b> promoter < /b> regions < /b> of < /b> genes ... binding sites of < /b> HBx and < /b> putative clinically associated direct target genes of < /b> HBx 68 Figure 3.2: Flowchart of < /b> experimental design for generation of < /b> ChIP-Seq data and < /b> gene expression profiles...
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Báo cáo khoa học: Fidelity of hepatitis B virus polymerase pptx
... course of < /b> HBV infection remains to be elucidated, but the genetic variations of < /b> HBV are possibly related to the infidelity of < /b> the HBV polymerase and < /b> reverse transcription strategy of < /b> HBV Fidelity of < /b> ... mechanism of < /b> hepatitis < /b> B virus polymerase resistance to lamivudine (3TC) and < /b> emtricitabine (FTC) J Virol 75, 4771–4779 Zoulim, F (1999) Therapy of < /b> chronic hepatitis < /b> B virus infection: inhibition of < /b> ... (1974) DNA of < /b> a human hepatitis < /b> B virus candidate J Virol 14, 384–391 Summers, J., O’Connell, A & Millman, I (1975) Genome of < /b> hepatitis < /b> B virus: restriction enzyme cleavage and < /b> structure of < /b> DNA extracted...
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Báo cáo sinh học: " Common Genotypes of Hepatitis B virus prevalent in Injecting drug abusers (addicts) of North West Frontier Province of Pakistan" doc
... agarose hepatitis < /b> B virus 2.5% agarose gel showing genotype specific bands in patients infected with hepatitis < /b> B virus M: 50 bp marker; Lane 2–3: HBV genotype A specific 68 bp band; Lane 4–5: HBV ... the transmission of < /b> major communicable diseases like Hepatitis < /b> B virus, Hepatitis < /b> C virus and < /b> Human Immunodeficiency Virus The seropositivity rate of < /b> Hepatitis < /b> B surface antigen (HBsAg) varies in ... Quantification of < /b> Hepatitis < /b> B virus genomic DNA by Real-Time detection Journal of < /b> Clinical Microbiology 2000, 37(9):2899-2903 Mahoney FJ: Update on diagnosis, management, and < /b> prevention of < /b> hepatitis < /b> B virus...
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Báo cáo hóa học: " Common Genotypes of Hepatitis B virus prevalent in Injecting drug abusers (addicts) of North West Frontier Province of Pakistan" potx
... agarose hepatitis < /b> B virus 2.5% agarose gel showing genotype specific bands in patients infected with hepatitis < /b> B virus M: 50 bp marker; Lane 2–3: HBV genotype A specific 68 bp band; Lane 4–5: HBV ... the transmission of < /b> major communicable diseases like Hepatitis < /b> B virus, Hepatitis < /b> C virus and < /b> Human Immunodeficiency Virus The seropositivity rate of < /b> Hepatitis < /b> B surface antigen (HBsAg) varies in ... Quantification of < /b> Hepatitis < /b> B virus genomic DNA by Real-Time detection Journal of < /b> Clinical Microbiology 2000, 37(9):2899-2903 Mahoney FJ: Update on diagnosis, management, and < /b> prevention of < /b> hepatitis < /b> B virus...
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Báo cáo hóa học: " Elective caesarean section versus vaginal delivery for preventing mother to child transmission of hepatitis B virus – a systematic review" pot
... transmission(MTCT) of < /b> HBV is one of < /b> the most important causes of < /b> chronic HBV infection [7-9] and < /b> remains one serious problem despite passive immunization (hepatitis < /b> B immune globulin at birth) and < /b> active ... collection of < /b> blood According to principles of < /b> medical ethics, we suggest neonate's umbilical blood should be chosen for detection of < /b> HBV DNA, which can largely relieve pains of < /b> newborns But it must be ... with HBV DNA-positive (HBV DNA > 103copies/ml) in sera of < /b> blood and < /b> their babies CAESAREAN SECTION DELIVERY AND < /b> PREGNANCY "MODE OF < /b> DELIVERY" AND < /b> PREGNANCY 10 #6 OR #7 OR #8 OR #9 Types of < /b> intervention...
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báo cáo hóa học:" High Prevalence of Hepatitis B Virus Markers in Romanian Adolescents With Human Immunodeficiency Virus Infection" ppt
... Most of < /b> these children became infected with HIV between 1988 and < /b> 1992 through the use of < /b> blood and < /b> blood products unscreened for HIV antibodies, and < /b> the use and < /b> reuse of < /b> disposable needles and < /b> ... hepatitis < /b> B core < /b> antigen (HBcAg), for antibody to hepatitis < /b> B surface antigen (HBsAg), and < /b> for antibody against HCV Sera positive for anti-HBc antibody were tested for HBsAg; sera positive for anti-HBs ... adolescents have decreased rates of < /b> clearance of < /b> HBsAg and < /b> HBeAg All subjects without HBe antigen had undetectable levels of < /b> HBV DNA, while the HBeAg presence was accompanied by high viral load values...
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Báo cáo y học: "i: Randomized controlled trial of Hepatitis B virus vaccine in HIV-1-infected patients comparing two different doses" ppt
... Research and < /b> Therapy 2006, 3:9 Background Hepatitis < /b> B virus (HBV) is one of < /b> the major causes of < /b> acute and < /b> chronic hepatitis < /b> worldwide that can be prevented by immunization [1,2] Co-infection with HVB ... development of < /b> the hepatitis < /b> B virus carrier state J Infect Dis 1991, 163:1138-1140 Koblin B, Taylor P, Rubinstein P, Stevens C: Effect of < /b> duration of < /b> hepatitis < /b> B virus infection on the association between ... Friedman L: Hepatitis < /b> B and < /b> human immunodeficiency virus: double trouble Gastroenterology 1991, 101:862-863 Bodsworth N, Cooper D, Donovan B: The influence of < /b> human immunodeficiency virus type...
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Báo cáo y học: " Characterization of Hepatitis B virus (HBV) genotypes in patients from Rondônia, Brazil" doc
... Page of < /b> Figure The maximum clade credibility (MCC) tree was estimated by Bayesian analysis of < /b> 383 S/POL sequences with 1306 bp of < /b> Hepatitis < /b> B virus strains The posterior probabilities ( > 0.95) of < /b> ... AJ, Omilabu SA, le Faou A, Muller CP: Phylogenetic analysis of < /b> the precore/< /b> core < /b> gene of < /b> hepatitis < /b> B virus genotypes E and < /b> A in West Africa: new subtypes, mixed infections and < /b> recombinations ... subgenotype of < /b> hepatitis < /b> B virus in Russia and < /b> the Baltic region J Gen Virol 2008, 89:1829-1839 64 Bertolini DA, Ribeiro PC, Lemos MF, Saraceni CP, Pinho JR: Characterization of < /b> a Hepatitis < /b> B virus...
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Báo cáo y học: "A novel nucleotide insertion in S gene of hepatitis B virus in a chronic carrier" pps
... of < /b> hepatitis < /b> B virus in Spain: identification of < /b> viral genotypes and < /b> prediction of < /b> antigenic subtypes by limited sequencing J Med Virol 2005, 76:176-184 Carman WF: The clinical significance of < /b> ... determinant variants of < /b> hepatitis < /b> B virus J Genl Virol 1997, 78:2639-2645 Alexopoulou A, Dourakis SP: Genetic heterogeneity of < /b> hepatitis < /b> viruses and < /b> its clinical significance Current Drug Targets ... contribute to HBsAg detection Clone sequencing confirmed the mixture of < /b> variant HBsAg and < /b> wildtype HBsAg High level of < /b> serum DNA viral load(>1 × 105 copies/mL) and < /b> 20% of < /b> wildtype HBsAg ensured HBsAg detection...
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Báo cáo khoa học: " An overview of molecular epidemiology of hepatitis B virus (HBV) in India" pot
... molecular epidemiology and < /b> clinical significance of < /b> hepatitis < /b> B virus genotypes, core < /b> promoter < /b> and < /b> precore < /b> mutations in eastern India, (ii) identify possible routes of < /b> introduction of < /b> HBV genotype C in ... epidemiology and < /b> clinical significance of < /b> hepatitis < /b> B virus genotypes, core < /b> promoter < /b> and < /b> precore < /b> mutations in Eastern India Intervirology 2008, 51:275-284 Datta S, Banerjee A, Chandra PK, Biswas A, ... sequence analysis of < /b> BCP /precore/< /b> core < /b> region of < /b> hepatitis < /b> B virus isolated from chronic carriers of < /b> the virus from Kolkata, Eastern India: low frequency of < /b> mutation in the precore < /b> region Intervirology...
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A comprehensive proteome analysis of hepatitis b virus associated hepatocellular carcinoma
... Hepatitis < /b> B virus Hepatitis < /b> B virus (HBV) is a 3.2kb partially double stranded DNA virus which can cause an acute and < /b> chronic inflammatory response from the liver The estimated number of < /b> HBV chronic ... Gene Ontology GRAVY Grand average of < /b> hydropathicity HBV Hepatitis < /b> B virus HBsAg Hepatitis < /b> B surface antigen HCV Hepatitis < /b> C virus HCC Hepatocellular Carcinoma HIF Hypoxia inducible factor hr Hour(s) ... factors of < /b> HCC have been well established These include persistent hepatitis < /b> B or C virus (HBV or HCV) infection, cirrhosis and < /b> aflatoxin B1 which accounts for almost 80% of < /b> all HCC cases (Bosch...
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Báo cáo y học: " Hepatitis B virus genotypes and precore and core mutants in UAE patients" ppt
... and < /b> precore < /b> mutant hepatitis < /b> B virus in carriers Hepatol Res 2002, 23:48-54 Yoo B, Park J, Kim HJ, Lee DH, Chan YJ, Park SM: Precore < /b> and < /b> core < /b> Promotor Mutations of < /b> Hepatitis < /b> B Virus and < /b> Hepatitis < /b> ... Aoyama K, Ohno N, Iwata K, Akahane Y, Baba K, Yoshizawa H, Mishiro S: The precore/< /b> core < /b> promoter < /b> mutant (T1762A1764) of < /b> hepatitis < /b> B virus: clinical significance and < /b> an easy method for detection J ... Sarrami-Forooshani R, Sabahi F, Sabouri E, Tavangar HR, Azizi M, Mahboudi F: Hepatitis < /b> B virus genotyping, core < /b> promoter,< /b> and < /b> precore/< /b> core < /b> mutations among Afghan patients infected with hepatitis < /b> B: a preliminary...
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Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C ppt
... underscore that chronic hepatitis < /b> B and < /b> hepatitis < /b> C are among the leading causes of < /b> preventable death worldwide Hepatitis < /b> B and < /b> hepatitis < /b> C are contagious liver diseases caused by the hepatitis < /b> B virus ... chronic hepatitis < /b> B and < /b> chronic hepatitis < /b> C prevents the majority of < /b> HCC cases because HBV and < /b> HCV are the leading causes of < /b> this type of < /b> cancer Key characteristics of < /b> hepatitis < /b> B and < /b> hepatitis < /b> C are ... for Prevention and < /b> Control of < /b> Hepatitis < /b> B and < /b> C http://www.nap.edu/catalog/12793.html INTRODUCTION 16 TABLE 1-1 Key Characteristics of < /b> Hepatitis < /b> B and < /b> Hepatitis < /b> C Hepatitis < /b> B Hepatitis < /b> C Causative...
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