... about their sexual behaviour, including the number of partners they had inthe 12 months preceding thesurvey Women and men were also asked about condom use inthe 12 months preceding thesurveyThe ... Using Using condoms condoms Limiting and limiting Limiting and limiting sexual sexual sexual sexual intercourse intercourse intercourse intercourse to one to one to one to one Using Using uninfected ... spent the night before the interview inthe household Each of the indices is expressed in standard deviation units (SD) from the median of the WHO Child Growth Standards adopted in 2006 The indices...
... and interpreting the findings of thesurveyand also provides indicators of the representativeness of thesurveyThe information is also useful in understanding and identifying the major factors ... mortality and infant and child health, mortality, and morbidity, in addition to the conventional areas that most demographicandhealth surveys cover Before deliberating on the findings of the survey, ... appreciation to the technical experts inthe different fields of population andhealth for their valuable input during various phases of thesurvey including the finalization of questionnaires, training...
... prevalence The preliminary report containing results of selected variables was released in October 2011, and this final report presents the details of the findings of thesurvey including results ... Ministry of Health for the overall co-ordination and undertaking of the voluntary counseling and testing (VCT) activities and to all members of institutions represented inthe 2011 EDHS Steering ... from the pretest exercise Main Training Recruitment of interviewers, editors, and supervisors for the main fieldwork was conducted inthe nine regions and two city administrations, taking into...
... technical experts inthe different fields of population andhealth for their valuable input inthe various phases of thesurvey including the finalization of the questionnaires, training of field ... 1991, and 2001 andthe recent preliminary findings from the 2011 census According to the preliminary 2011 census findings, the population of the country stands at 26.6 million, with an increase ... in this survey is a measure that has been used in many DHS and other countrylevel surveys to indicate inequalities in household characteristics, inthe use of healthand other services, and in...
... measuring children, mock interviews and role plays between participants inthe classroom andinthe neighboring villages At the end of the main training 123 individuals were retained to work as the ... Uganda DemographicandHealthSurvey 2000-01 Calverton, Maryland, USA: UBOS and Macro International Inc Uganda Bureau of Statistics (UBOS) and Macro International Inc 2007 Uganda Demographicand ... spent the night before the interview inthe household Each of the indices is expressed in standard deviation units (SD) from the median of the WHO Child Growth Standards adopted in 2006 The indices...
... violence since they were 15 and one in four reported experiencing violence inthe 12 months preceding thesurveyThe main perpetrators are husbands, and to a lesser extent, teachers, mothers, fathers, ... acknowledge the contributions of the various agencies and institutions that culminated inthe compilation of the 2008-09 Kenya DemographicandHealthSurvey (KDHS) Thesurvey was conducted in close ... meet the following objectives: • Restoring economic growth within the context of a sustainable macroeconomic framework • Strengthening the institutions of governance • Restoring and expanding the...
... population andhealthsurvey conducted in Nepal as part of the global DemographicandHealth Surveys (DHS) program The 2011 NDHS was implemented by New ERA under the aegis of the Ministry of Healthand ... stayed the night before the interview inthe household Each of the indices is expressed in standard deviation units (SD) from the median of the WHO Child Growth Standards adopted in 2006 The indices ... three-week training on the paper-based questionnaires and biomarkers while ICF Macro staff led the two-week training on the use of PC tablets The training included theoretical and practical sessions,...
... suggests that the mitochondrial injury is caused by opening of the mPTP There is evidence that ADP inhibits opening of the mPTP by occupying binding sites located inthe inner and outer mitochondrial ... Protein content was measured according to the Bradford method [47] using BSA as the standard In separate experiments we determined protein values with the Bradford and Lowry methods From the comparison, ... cyclosporin A (lane and lane 4, respectively) To test the possibility that mitochondrially generated ROS could be involvedinthe mechanism of membrane permeabilization, we determined H2O2 inthe incubation...
... the D2 domain and D(495–535) inthe D3 domain, are involvedinthe interaction with CD, and that this interaction enhances the catalytic activity of the enzyme Our results show that the interaction ... interaction between the N- and C-terminal domains of SSIII in vitro Mapping of the CD-binding region inthe N-terminal SBDs In order to identify the SBD region required for the SBD–CD interaction, we ... conservation of the tryptophan in binding site II and an aromatic residue (mainly tryptophan or tyrosine) in binding site I [22] We have shown that the tryptophan residue involvedin binding site II...
... Synoviolin is involvedinthe degradation of nicastrin gene p53 [19] and Parkin-associated endothelin receptor-like receptor [20] In this study, we addressed whether Synoviolin is involvedinthe ... Supporting Information) We also determined the levels of c-secretase-unrelated ER protein (calnexin) and cytoskeleton protein (tubulin) in these cells as the internal control proteins The calnexin and ... ubiquitination confer specificity to the ubiquitin system by directly interacting with the substrate proteins and helping to transfer ubiquitin to them Therefore, to determine whether NCT is the...
... are involvedinthe transmission of mechanical signals to signaling pathways Inthe M line, mechanical stimulation activates the interaction of a protein complex with the kinase domain of titin, ... control, an interaction test of calpain and N2A-titin is performed (upper left panel) The yeasts carrying calpain and CARP grow on the selective medium, indicating that CARP and calpain interact ... slower in wildtype muscles than in calpain deficient muscles (Fig 3C), suggesting that the interaction between CARP and titin is reinforced inthe presence of calpain These results suggest that the...
... relaxin-3 is considered to be different from that of other relaxin proteins involvedinthe growth and remodeling of reproductive and other tissues during pregnancy [10] Inthe mouse and rat brain, ... expression and function inthe hypothalamus sion and leads to an increase in relaxin-3 mRNA levels inthe NI [12] On the other hand, relaxin-3-positive neurons project fibers to the hypothalamus, and ... relaxin-3 transcripts inthe NI [28] This supports the idea that relaxin-3-expressing neurons inthe NI (and therefore relaxin-3) play a role inthe central stress regulating system by mutual interaction...
... Glc binding (Fig 8B,C) The changes inthe interhelical interactions point to a major contribution inthe dynamic communication between the L- and S-domains and thus inthe transition from the super- ... residues inthe L-domain and connecting region II which are potentially involvedinthe binding of D-glucose inthe super-open state (PDB identity: 1v4t) The structural images were generated using ... S-domain (residues T168 and K169) (Fig 1B) To identify the contact residues involvedinthe initial binding of Glc to the super-open state (Fig 1C) of this two domain hinge-bending enzyme, all the...
... 23b, and exon 24 In conclusion, the alternative splicing maintains the reading frame along the entire protein, therefore the protein variants are identical inthe amino-terminal end up to the ... andthe corresponding gene has been cloned from human [23] Inthe present study we have cloned the murine genes coding for the enzymes involvedinthe salvage pathway of GDP-L-fucose L-fucokinase ... human fucokinase cDNA is similar to the long splice variant of mouse fucokinase cDNA at the 3¢ splice region The first and third methionines inthe murine sequence, inthe upstream end of the CDS,...
... chlorine and methyl functional groups at the 5-position Together, these results provide insight regarding the mechanism, the substrate binding site andthe role of the metal cofactor inthe enzyme ... ± 0.3 Thein uence of the two metal ions on the kinetic parameters for HPDA hydration by BphH is shown in Table The Km values were similar with either metal cofactor On the other hand, the kcat ... roles of the cation include the activation of water for the hydration reaction and ⁄ or the stabilization of the anion transition state Inthe latter case, if the substrate coordination to the metal...
... transformed following the instructions provided by the manufacturer (Invitrogen) The strain harbouring the correct construction was incubated in selecting liquid medium according to Invitrogen recommendations, ... at 30 °C for 20 The esters formed were extracted with 250 lL pentane containing lLÆL)1 a-pinene as internal standard, vortexed for and lL of the pentanic phase was injected into the GC for analysis ... playing a role in activity However, inthe BEAT sequence, which encodes an enzyme involvedin scent production, glycine was substituted by methionine inthe conserved triad H-x-x-x-DG In yeast AATs...
... adhesion molecules (ICAM-1) inthe brain andin cultured astrocytes and brain endothelial cells [510] These inflammatory mediators play a critical role not only inthe initiation and propagation of ischemica/ ... chemokine-producing cells inthe brain [34,37], and astrocyte-produced MCP-1 directs the transmigration of monocytes and macrophages across the BBB to the sites of axonal injury inthe brain [33,37] ... of inflammatory mediators also initiates an inflammatory process Infiltration of peripheral inflammatory cells into the brain is a critical step inthe development and progression of the neuroinflammation...
... to a thorough clinical and laboratory investigation, including electroencephalogram (EEG) and high-resolution brain magnetic resonance imaging (MRI) scanning, so as to categorize their epilepsy ... focus of the present study was exclusively on interictal mood disorders It should be noted that the distinction between interictal (i.e occurring inthe periods inbetween epileptic seizures) and ictal ... it is calculated by multiplying the regression coefficient by the ratio of the standard deviation (SDx) of the independent variable to the standard deviation (SDy) of the dependent variable (β...
... Arsenic exerts its effect by inhibiting the activities of several enzymes, especially those involvedin cellular signaling pathways and DNA synthesis and repair During the past centuries, a number ... contributions YZ and AY are researchers working in cancer biology and carried the study QL and YB undertook the Statistical analysis QZ along with MZ designed the work and interpreted the results QZ and MZ ... contributed to the writing of the manuscript All the authors read and approved the final manuscript 17 Acknowledgements This study was sponsored by Zhejiang Provincial Top Key Discipline in Surgery and...
... significant inthe inhibitory effect of Bee venom on the LPS-induced, andinthe inhibitory effect of melittin on the SNP-induced NF-κB in THP-1 cells by 10 μM of SP600125 JNK inhibitor suppressed the inhibitory ... together, our data indicate that inhibition of JNK signal is the most involvedinthe inhibitory effect of melittin and bee venom on the LPS and SNP-induced activation of NF-κB as well as inthe ... melittin and bee venom on iNOS and COX-2 expression, and on NO and PGE2 generation To investigate whether the suppressed effect of SP600125 on the inhibitory effect of bee venom and melittin on the...