... magnification of original spectra. (D) Absorption spectra of the acid-denatured K13N mutant (spectrum a), of the K13N mutant after 3 ms of mixing with 40 mM sulfate (spectrum b), and after 5 s of mixingwith ... reagents used were of analytical grade.Construction of horse cytochrome c expressionsystemA version of the horse cytochrome c synthetic gene wasdesigned on the basis of the sequence of a previously ... of electrostaticrepulsions in the acidic molten globule of cytochrome c.J Mol Biol 222, 679–686.13 Jordan T, Eads JC & Spiro TG (1995) Secondary andtertiary structure of the A state of...
... years and the other members of the Executive Board for terms of office of between five andeight years. No term of office shall be renewable. The number of members of the Executive Board may be ... conditions of Accession of the Czech Republic, the Republic of Estonia, theRepublic of Cyprus, the Republic of Latvia, the Republic of Lithuania, the Republic of Hungary, the Republic of Malta, ... of office shall be eight years and shall not be renewable.Only nationals of Member States may be members of the Executive Board.11.3. The terms and conditions of employment of the members of...
... microfinance sector, which in the aggregate exceed 10% of its total assets. 6 Areas of ConcernThe advent of MFIs in the Microfinance sector appears to have resulted in a significant increase ... demand for microfinance credit and on the other, there was a limitation on the capacity of not-for-profit entities to meet this demand. When for-profit entities emerged, microfinance was seen ... consumption smoothing, acquisition of household assets, housing, emergencies, etc. A recent study by Centre for Microfinance of borrowers in Hyderabad indicates that Microfinance is useful in smoothening...
... rice left. (không phải là: There is not much of rice left.) A lot of - lots of Không có sự khác nhau nhiều giữa a lot of và lots of. A lot of và lots of đều mang tính chất thân mật, suồng sã, ... credit cards. A large amount of, a great deal of , a large number of Cách diễn đạt này mang tính tương đối trang trọng. Sau A large amount of và a great deal of là danh từ không đếm được. ... Không có sự khác nhau nhiều giữa a lot of và lots of. A lot of và lots of đều mang tính chất thân mật, suồng sã, đứng trước danh từ không đếm được, danh...
... practice nurses, who can fulfill some of the roles of doctors in certain situations. Japan doesnot offer such licenses, and the political influence of existing professional organizations is so strong ... supply of doctors stratified by sex and age Figure 4 Addition of estimated number of new doctors.Table 1 Yearly pass rates of national examination formedical doctorsYear Pass rate Number of ... currentlevel, the percentage of all high school students thatqualify for medical school will increase as the populationdecreases; if the quota is increased, the percentage of qualified students will...
... organization consisted of 5'untranslated region (5'UTR) of 25 nt (1–25), ORF-1 of 5127 nt (26–5152), ORF-2 of 1983 nt (5190–7172),ORF-3 of 372 nt (5249–5520) and 3'UTR of 93 nt (7173–7265), ... http://www.virologyj.com/content/4/1/98Page 6 of 7(page number not for citation purposes)Phylogenetic trees constructed using MEGA software depicting genotypic status of SH-SW-zs1 on the basis of full-length genome sequence of 39 ... units) of AMV Reverse Transcriptase (TakaRa, Japan) and 1 ul(25 mM) of external antisense primer. The first round PCRwas carried using 10 ul of the synthesized cDNA and anexternal set of forward...
... Correlation of HFS-36 subscale and severity of HFS before BTX treatment and difference of HFS-36 before and after treatmentCorrelation of HFS-36 subscale and severity of HFS Difference of HFS-36before ... part of the response of treatment, whereas we only used the changes of spasmseverity as treatment response. Since the self-perception of treatment response strongly influenced the self-rating of HRQoL, ... thesubscales of motility, ADL, emotional well being, andbodily discomfort (Table 3). Most of subscale scores of HFS-36 improved significantly after treatment, exceptsubscales of social support...
... literature [4,11,21,25].Thepsychosocialsupportofthefamilyshouldbethepart of health care of chronically ill children. In light of the apparent limitations of parents’ assessments inapproximating ... health-related quality of life in childrenwith ESRD: performance of the generic and ESRD-specific instrument of the Pediatric Quality of Life Inventory (PedsQL). American Journal of Kidney Diseases ... determination of chronic stress. Annals of the New York Academy of Sciences 2007, 1113:325-38.30. Felder-Puig R, Frey E, Proksch K, Varni JW, Gadner H, Topf R: Validation of the German version of the...
... 1Department of Epidemiology and Health Policy Research, College of Medicine, University of Florida, Gainesville, FL, USA, 2Department of Health Policy and Management, Bloomberg School of Public ... theimpact of fluctuations and acute increaseof glycemia(hyperglycemic spikes) on health [13,14]. Additionally,hyperglycemic symptoms and diabetic complications aremajor determinants of HRQOL ... generate a small range of values forMID [20-23]. The strength of using multiple approachesto establish a range of MID is to demonstrate variabilityamong estimates.The main purpose of this study was...
... hospitals of the city. A total of 190 families of Bra-zilian children between the ages of 2 and 18 years, of bothgenders, with malignant neoplasm in various phases of treatment or control of the ... on the quality of life of patients. Moreover,decisions for the implementation of improvements inpublic healthcare may be adopted based on the impact of interventions on quality of life [1]. However, ... indicators of BioMed CentralPage 1 of 11(page number not for citation purposes)Health and Quality of Life OutcomesOpen AccessResearchMeasurement properties of the Brazilian version of the...
... factor of second-order factor. BioMed CentralPage 1 of 15(page number not for citation purposes)Health and Quality of Life OutcomesOpen AccessResearchValidation of the Korean version of the ... RMSEA is one of absolute fit indi-ces and a measure of discrepancy between the observedand model implied covariance matrices adjusted fordegrees of freedom. The values of RMSEA of .05 or lessindicate ... is an estimate of thespread or separation of persons on this measured variable.Item reliability index is the estimate of the replicability of item placement within a hierarchy of items along...
... organization consisted of 5'untranslated region (5'UTR) of 25 nt (1–25), ORF-1 of 5127 nt (26–5152), ORF-2 of 1983 nt (5190–7172),ORF-3 of 372 nt (5249–5520) and 3'UTR of 93 nt (7173–7265), ... http://www.virologyj.com/content/4/1/98Page 6 of 7(page number not for citation purposes)Phylogenetic trees constructed using MEGA software depicting genotypic status of SH-SW-zs1 on the basis of full-length genome sequence of 39 ... shown in Figure 1, 3'RACE band of the expected sizewas obtained. The 3' terminus of this study had 93 nucle-otides upstream of the polyA. The sequence of 3'UTR was:TTT ATT CTT CTT...
... article as: Matsumoto et al.: Role of the VEGF-Flt-1-FAKpathway in the pathogenesis of osteoclastic bone destruction of giantcell tumors of bone. Journal of Orthopaedic Surgery and Research ... confocal laser scanningmicroscopy.Tissue culture of giant cell tumors of bonePrimary cultures of GCTs were obtained from surgicalsamples of lytic bone lesions. As previously described[6], ... directlystimulates the formation of MNCs within the tumor.These results suggest that the effects of GCT-CM,including the stimulat ion of chemotaxis and prolifera-tion of rOPCs but not osteoc lastogenesis,...
... article as: Matsumoto et al.: Role of the VEGF-Flt-1-FAKpathway in the pathogenesis of osteoclastic bone destruction of giantcell tumors of bone. Journal of Orthopaedic Surgery and Research ... pathway.Methods: The motility of OPCs cells was assessed by a chemotaxis assay and the growth of OPCs was examinedusing a cell proliferation assay. The expression of VEGF and activatio n of Flt-1 and FAK ... pathogenesis of bonedestruction of GCTs.BackgroundGiant cell tumors (GCTs) of bone are rare primary ske-letal neoplasms that occur in young adults [1]. The his-tological phenotype of GCTs is...