... view ofthesmallcellcarcinoma showing hyperchromatic nuclei, nuclear moulding and clumping ofthe nuclear chromatin keeping with a neuroendocrine carcinomaofsmallcell type In the absence of ... therefore it is unclear whether her family history oflung cancer had a causative role either Figure hyperchromatic view ing ofthe showing4 nuclear chromatin ofthesmallcellcarcinoma High-power ... nature ofthe disease Therapeutic modalities are determined by the location and extent of disease Chemotherapy remains the treatment of choice The role of radiotherapy and sur- Page of (page number...
... contrast, most ofthe other studies based their analyses on patients with BC or large cellcarcinoma Conclusions Although there is a low incidence of basaloid squamous cellcarcinomaofthe lung, it ... that were in line with the diagnostic criteria of basaloid squamous cellcarcinomaofthe lung, and were reclassified as basaloid squamous cellcarcinoma Consequently, a total of 120 pathological ... http://www.cardiothoracicsurgery.org/content/6/1/10 Page of Figure The actual survival time of basaloid squamous cellcarcinoma and PDSC patients in stage I and stage II, p = 0.145 Discussion Basaloid squamous cellcarcinomaofthelung as...
... Abbreviations NSCLC: non -small celllung carcinoma; LCNEC: large cell neuroendocrine carcinoma; LCC: large cell carcinoma; SCLC: smallcelllung carcinoma; CSC: cancer stem cell; LC: liquid chromatography; ... expression of AL1A1 in lung cancer cell lines, especially in AC cell lines Page 11 of 13 compared to LCC and SCLC cell lines [22-24] To our knowledge, however, this is the first report ofthe statistically ... common characteristics of LCNEC and SCLC The preferential expression ofthe cancer stem cell markers in LCNEC over SCLC suggests that the mechanism of increasing the extent of malignancy in LCNEC...
... were performed The histogenesis of MCC is controversial Possible cells of origin include the epidermal Merkel cell, a dermal Merkel cell equivalent, a neural-crest-derived cellofthe amine precursor ... very helpful MCC from other forms of cancer, such as sebaceous cyst, smallcelllung cancer (SCLC) and lymphoma, smallcell melanoma Each of these cancers has a unique profile as defined by special ... Management of Merkel cellcarcinoma Expert Rev Anticancer Ther 2001, 1:441-445 14 Meeuwissen JA, Bourne RG, Kearsley JH: The importance of postoperative radiation therapy in the treatment of Merkel cell...
... Considering these findings in addition to the characteristics of CDC similar to those of urothelial cancer, chemotherapy is the currently favored approach for patients with metastatic CDC In the case ... as one ofthe most powerful agents against metastatic RCC [8], and showed a partial response to this drug Recently, the favorable clinical activity of sunitinib against non-clear cell carcinomas, ... treated with sunitinib rather than systemic chemotherapy, considering her poor performance status After courses of sunitinib therapy with 37,5 mg daily schedule, metastases to the lungs and left rib...
... Extrapelvic spread of squamous cellcarcinoma (SCC) ofthe cervix to thesmall bowel is rare with only reported cases in the English literature since 1981(PubMed, Medline) We report the case of a 49-year-old ... comprehensive review ofthe published cases ofsmall bowel metastases from squamous cellcarcinoma (SCC) ofthe cervix in the English literature since 1981 including details of : i) reference #, ... sites of such occurrences are the liver, lungs, and bone marrow The gastrointestinal tract is involved in approximately 8% of patients with carcinomaofthe cervix; these being commonly found in the...
... from the pluripotential surface epithelium ofthe ovary and from cells with urothelial potential, rather than from a benign or proliferative Brenner tumor precursor Themetastatic pathways ofthe ... urothelial carcinomaofthe bladder and ovarian transitional cellcarcinoma Arch Pathol Lab Med 2005, 129:194-9 Shen K, Lang J, Guo L: Overexpression of p53 in transitional cellcarcinomaofthe ... Molecular profile of advanced stage transitional cellcarcinomaofthe ovary Am J Obstet Gynecol 1997, 177:120-5 Shen K, Lang J, Guo L: Overexpression of C-erbB3 in transitional cellcarcinomaof the...
... consent ofthe patient or her next of kin for publication could not be obtained A copy ofthe waiver of consent from the Research Ethics Office, University of Saskatchewan, has been submitted to the ... and an open wedge left lung biopsy Pathological examination ofthe left lung biopsy confirmed the presence of neoplastic sheets of cells classically distributed along the septal vessels, perivascular, ... distant, extrapelvic sites such as the lungs, para-aortic lymph nodes, and bones occur in the advanced stages ofthe cancer [2,7] Metastases to thelung comprise up to 3% of cervical cancer treatment...
... the size ofthe tumor The slightly hyperintense area in the head ofthe pancreas had diameters of barely 2.4 × 1.1 cm, with a small (1.0 cm) residual precaval lymph node (Figure 4) There had ... curative resection of an ACC Comparison ofthe histology ofthe biopsy and the surgical specimen showed large differences, because after chemotherapy there were necrotic areas, and the vital tumor ... chemotherapy was given to the patient Altogether, the patient was treated with cycles of 5-FU monotherapy (220 mg/m2/d); treatment occurred over eight weeks with a break of two weeks per cycle There...
... and the negativity for TTF-1 are important in the differential diagnosis from smallcell neuroendocrine lungcarcinoma [25-27] The monotonous nature ofthe dermal round cell infiltrate and the ... [6-8] Therapeutic options depend on the stage ofthe disease at the time of presentation whereas the most important prognostic factor is the absence of nodal involvement [34] Surgery remains the ... Trascription Factor – and cytokeratin 20 aids the distinction ofsmallcellcarcinoma from Merkel cell carcinoma, but not pulmonary from extrapulmonary smallcell carcinomas Arch Pathol Lab Med 2001,...
... kidney Clear -cell carcinomaofthe breast, resembling clear -cell carClear -cell carcinomaofthe breast, resembling clear -cell carcinomaofthe kidney The lobular arrangement and the fine vascular ... Mackenzie DH: Clear -cell carcinomaofthelung J Pathol Bact 1964, 87:25-27 Seo I, Tomich CE, Hull MT, Warfel KA: Clear cellcarcinomaofthe larynx: a variant of mucoepidermoid carcinoma Ann Otol ... Conclusion Clear cell neoplasms arise throughout the body The vacuolated cytoplasm in many of these tumors can be attributed to large quantities of glycogen, as in clear cell carcinomas ofthe vagina,...
... Squamous CellCarcinomaofthe skin ofthe trunk and limbs: The incidence of metastases and their outcome Aust N Z J Surg 1992, 62:697-701 Ames FC, Hickey RC: Squamous cellcarcinomaofthe skin ofthe ... number of lymph node metastasis was the presence of previous lesions on the skin of 22 patients with lymph node metastasis over the time pre- The 24 cases of amputations (42.1%) also reflected the ... factor for development of lymph node metastasis, the presence of scar or ulcers previously in the area ofthe tumor This was observed also in other studies [10,18] The association of UV damage and...
... glassy cell display large the cervix: the undifferentiated, Glassycells carcinomaof nuclei with prominent nucleoli and Glassy cellcarcinomaofthe cervix: the undifferentiated, glassy cells ... with the patient, who nevertheless decided to undergo only strict follow-up procedures The patient was then followed with gyneco- Here, we report the case of a stage IB1 cervical glassy cellcarcinoma ... study and collected the clinical data MP participated in the design ofthe study and collected the clinical data AC carried out the histopathological evaluation GS conceived ofthe study, and participated...
... patches of squamous cells can be found in adenocarcinoma ofthe breast and from metastasis of squamous cellcarcinomaof an origin somewhere else The etiology and pathogenesis of squamous cellcarcinoma ... squamous cellcarcinoma when the malignant cells are all ofthe squamous cell type, there is no relation with the skin and if there is no indication for a primary location somewhere else in the body ... aspiration (FNA) ofthe swelling was taken The pathology report confirmed the presence of a malignancy The pathologist described atypical epithelial cells with polymorphism ofthe nucleoli, and the conclusion...
... Reviewed charts, gathered data, and drafted the manuscript M.G.H.: Aided in the design ofthe study, helped draft the manuscript D.W.L.: Aided in the design ofthe study, helped draft the manuscript ... the growing body of data supporting the use of IMRT with SIB for anal cancer Regional control was excellent, despite the common use of low doses per fraction Limitations of our data include the ... after the diagnosis of anal cancer; the patient was disease free at the time of death The second patient died of sepsis associated with metastatic anal cancer 10 months after diagnosis The third...
... radiative therapy ofcarcinomaofthe prostate A report on 15 years of experience Radiology 1973, 106:407-418 Kastendieck H, Altenahr E: The squamous cellcarcinomaofthe prostate as an example of ... cellcarcinomaofthe prostate: presentation of a case and review ofthe literature Actas Urol Esp 1997, 21:931-935 Ulloa SA, Iturregui JR, Amezquita M, Ortiz VN: Squamous cellcarcinomaofthe ... variants of adenocarcinoma and other carcinomas of prostate: pathologic criteria and clinical significance Mod Pathol 1997, 10:612-619 Mott LJ: Squamous cellcarcinomaofthe prostate Report of cases...
... KS, SH, KI did the assistant ofthe operation NM diagnosed h the pathology of this case TS was the professor ofthe surgical science and had a guide All authors read and approved the final manuscript ... included among carcinomas of salivary-gland types along with adenoid cystic carcinoma according to the WHO histological classification oflung cancer MEC is characterized by a mixture of mucusproducing, ... ofthe tumor Figure Chest radiography revealed a mass shadow in the left lower lung field tumor had a keratin profile of CK7 (+), CK20 (-), and CK5/6 (+), and was determined to be a primary lung...
... M: Myoepithelioma ofthe lung: report of two cases and review ofthe literature Lung Cancer 1998, 20:47-56 18 Masuya D, Haba R, Huang CL, Yokomise H: Myoepithelial carcinomaofthelung Eur J ... Epithelialmyoepithelial carcinomaofthelung A case report and review ofthe literature Arch Pathol Lab Med 2003, 127:e177-180 Cagirici U, Sayiner A, Inci I, Veral A: Myoepithelioma ofthelung ... Epithelial-myoepithelial carcinomas ofthe bronchus Am J Surg Pathol 2001, 25:1508-1514 Cho KJ, el-Naggar AK, Ordonez NG, Luna MA, Austin J, Batsakis JG: Epithelial-myoepithelial carcinoma of...
... on the dorsum ofthe nose: the lesion bled spontaneously at the examination and biopsy confirmed the diagnosis of basal cellcarcinomaofthe skin Our patient refused the surgical excision ofthe ... metastases to the nose dorsum [5] In the case that we present, the histological type ofthe skin lesion as a basal cellcarcinoma and the long survival after the local control of both tumors ... two principal points of discussion; the first one concerns the relationship between the skin and cervical tumors, and the second one concerns the origin ofthe neuroendocrine metastatic disease...
... drinkers Sequence analysis of exon 10 ofthe CHK2 gene was performed for all patients However, none ofthe patients showed the presence ofthe 1100delC variant Discussion None ofthe investigated 91 ... patients, they did not detect any truncating mutation Therefore, we were able to confirm these results Nevertheless, they found the missense I157T mutation in 4.1% ofthe cases In this study, the incidence ... compliance with the Helsinki Declaration This study was reviewed and approved by the ethics committee ofthe University of Düsseldorf Sequencing ofthe CHK2 exon 10 including the 1100delC variant...