... expression of genes involvedin sugar and acid biosynthesis should be designed In the second case, candidate genes should be identified and transferred into breeding lines The emerging information on ... greater impact on generating differences in texture profiles than environmental growth conditions The genetic variation of such traits has been attributed to the joint action of many QTLs [29] ... factor determined the location of Sarno ecotypes in the lower left-hand part and those of Sorrento in lower right-hand part of the graphic Instead, the PCA plots obtained by combining PC1 with...
... patterns in the subtropical regions of Mexico and Florida (Ingraham et al, 1974; Thatcher et al, 1984) andin the very hot and arid environmental conditions of Arizona (Monty, 1984) and Israel ... records on SG in adjacent calvings i (Patterson and Thompson, 1971) = RESULTS The distribution of data for number of services per conception for different calvings is shown in table II Only 43.86% of ... vector of observations; (3 is a vector of fixed effects including age and herd-year-season of calving (natural trimester); s is as vector of random sire effects and e is a vector of random residuals,...
... obstruction, pulmonary hyperinflation and gas trapping in addition to ventilation inhomogeneities andin conjunction with CFTR genotyping provides a means for monitoring functional progression in CF ... infection found by Kerem et al [91] More noteworthy, is the finding that in addition to age of onset of chronic P aeruginosa infection, colonization status at the time oflung function evaluation ... The relationships between pulmonary hyperinflation and gas trapping and deterioration oflung function in CF are presented here using longitudinal data Previous investigations have demonstrated...
... patient inclusion criteria, duration of intubation, dosage, timing of treatment and risk levels of developing stridor Only the last two criteria (risk levels of develop- ing stridor and timing of ... (logarithm RR of Figure Risk of reintubation according to the studied population Risk ratio of reintubation rate for the individual randomised controlled trials comparing sterpopulation oids with control ... inverse of the difference of the proportion of patients who had any event in the steroid groups and the control groups CIs of the NNT were constructed by inverting and exchanging the limits of...
... of Mid1p in the assembly of actomyosin ring Conventional methods fail to dissect the potential function of Mid1p in ring assembly from its role in ring positioning, because loss of function of ... overlapping role in proper ring positioning Interestingly, Mid1p, Gef2p and Blt1p, together with the protein kinase Cdr1p and the kinesin-like protein Klp8p are all components of the interphase ... failure in SIN activation leads to defects in ring constriction and septum deposition, hyperactivation of SIN activity, such as Plo1p overexpression, Spg1p overexpression or loss of function of Cdc16p...
... 1: Introduction 1.1 Cells involvedin neuroinflammation 1.1.1 Microglia 1.1.2 Astrocytes 1.2 Neuroinflammation and cognition 1.2.1 Effect of cytokine on cognition 1.2.2 Effect of inflammation on ... 3.14 Effect of increasing dose of LPS in NOR T1 56 3.15 Effect of increasing dose of LPS in NOR T2 57 3.16 Effect of increasing dose of LPS in FC 58 3.17 Effect of increasing dose of LPS in LABORAS™ ... dosing on Arc expression in cortex and hippocampus 81 Effect of increasing LPS dosing on synapthophysin in cortex and hippocampus 82 3.36 Effect of increasing LPS dosing on APP in cortex and...
... simulations, and contributed in revision of the manuscript TS and AHR helped in discussion of the data and revision of the manuscript DRO participated in study design, data discussion and revision of ... needing knowledge on the combination of underlying biological information The presented results were obtained in a preclinical study in prostate cancer xenografts, and suggest that the combination ... applications, which also inspired us to implement and test this approach The BPNN architecture consists of many identical nodes, or neurons, mainly consisting of nonlinear activation functions The...
... Tan, Y.W., Hong, W and Liu, D.X (2012) Binding of the 5'-untranslated region of coronavirus RNA to zinc finger CCHC-type and RNA-binding motif enhances viral replication and transcription Nucleic ... of about 400 amino acid residues, contains two structural domains, the N-terminal RNA-binding domain and the C-terminal dimerization domain joined by a linker region (19) The coronavirus N has ... and a long endodomain at its C-terminus and functions in dimers The main function of M is in the adaptation of regions in the intracellular membranes, at the endoplasmic reticulum-golgi intermediate...
... Expression analysis of non-sulphated chondroitin in 111 prostate adenocarcinoma 4.1.2.1 Localization of non-sulphated chondroitin in 111 prostatic tissues 4.1.2.2 Comparison of non-sulphated chondroitin ... Comparisons of chondroitin sulphate staining amongst each 149 subtype in the peritumoural stroma Table 4.16 Association studiesof different chondroitin sulphate staining 152 intensities with clinicopathological ... core protein Addition of first galactose in linkage region Addition of second galactose in linkage region Transfer GlcA to linkage region Initiates biosynthesis of CS/DS biosynthesis by adding the...
... points 23 FIGURE 2.1 DNA replication licensing control by Geminin and CDKs 42 during the cell cycle FIGURE 2.2 Geminin Binding Domain of Human Cdt1 and Cdt1 44 Binding Domain of Human Geminin ... structural information will prove useful in elucidating how Cdt1 and Geminin interact at the protein level We identified, cloned and expressed (in bacterial cells) the geminin-binding domain of human ... (Activation) CDKs Geminin (Licensing) Figure2.1 DNA replication licensing control by Geminin and CDKs during the cell cycle In metazoa, Geminin, present from the onset of S phase to the end of M...
... [17], redox sensing [18] and the coordination of metal cofactors [19] The functional importance of the conserved cysteine residues in iron–sulfur cluster coordination and protein disulfide reductase ... [4Fe–4S] in WhiB proteins remains very high Protein ligands for the canonical clusters are typically sulfide ions of cysteines The involvement of four conserved cysteines in the coordination of the ... denaturing or in- column refolding conditions Fig S4 Effect of air oxidation on the stability of [2Fe–2S] cluster of various WhiB proteins Fig S5 Insulin disulfide reduction assay of apoWhiB5, WhiB6 and...
... along the length of the QR, which reduces the confinement of the exciton, and thus, the coulomb interaction of the electron and hole for a given bound exciton is reduced and exciton−exciton interactions ... exclusion principle) Thus, the TA rise time corresponds to electrons being excited high into the conduction band (CB) followed by intraband relaxation to the band edge Presented in Figure 5A and ... NCs and the reduction in surface ligands from the hydrazine treatment samples on intraband relaxation is less significant For both QDs and QRs, the thin-film samples exhibit intraband relaxation...
... along the length of the QR, which reduces the confinement of the exciton, and thus, the coulomb interaction of the electron and hole for a given bound exciton is reduced and exciton−exciton interactions ... exclusion principle) Thus, the TA rise time corresponds to electrons being excited high into the conduction band (CB) followed by intraband relaxation to the band edge Presented in Figure 5A and ... NCs and the reduction in surface ligands from the hydrazine treatment samples on intraband relaxation is less significant For both QDs and QRs, the thin-film samples exhibit intraband relaxation...
... thermonuclease (nuc) [5], fibronectin binding protein A (fnbA) and fibronectin binding protein B (fnbB) [4], alpha-hemolysin (hla) and beta-hemolysin (hlb) [4], collagen binding protein A domain ... fibronectin-binding proteins of S aureus are important virulence factorsand contribute to bacterial adhesion and to invasion of the bovine mammary gland [19] However, mutants defective in either ... et al [30] and Akineden et al [1], and could be explained by a combined location of these genes on pathogenicity islands [3,18] andon a plasmid [36] The importance of toxin formation of S aureus...
... impact of variance heterogeneity ongenetic evaluation, predictions of breeding values and selection outcomes were obtained from BM and from analyses assuming constant additive geneticandenvironmental ... offspring selections based on net PBVs and within-family breeding values Predictions of within-family breeding values for cloned offspring are expected to be more accurate than for uncloned offspring, ... combining ability of the parents and the variance due to differences among clones within full-sib families both contain portions of the additive genetic variance In addition, by using cloned...
... shared environmentalfactors (C) and nonshared environmentalfactors (E) was used for VC and FEV The comparisons of variance models indicated that the importance ofgeneticandenvironmental ... function in an Australian population: contributions of polygenic factorsand the Pi locus to individual differences inlung function in a sample of twins Ann Hum Biol 1983, 10(6):547-56 Redline ... or unmeasured, factors: additive geneticfactors (a2), shared environmentalfactors (c2) or dominant geneticfactors (d2), and non-shared environmentalfactors (e2), which also include measurement...
... were involvedin a dairy selection scheme and belonged to two categories: young rams under progeny testing and proven adult rams Only records of ejaculates corresponding to the intensive period of ... rams only), rank of collection within season, breeding value for milk production in quartiles and all two-way interactions with biological meaning For each model, variance and covariance components ... all traits in both breeds The year of collection was one of the two principal causes of variation in both breeds and for all traits A decrease of concentration with years was observed in both age...
... MJ/kg and 13% crude protein) and housed in single-hen cages A more detailed description of the lines and the environmental conditions can be found in Liljedahl and Weyde (1980) The traits considered ... additive genetic component of variance and the environmental component increased with advancing age for the trait egg number, as shown in figures and The slope of the linear regression for the environmental ... early and late reproductive fitness as a result of genotype-environment interaction arising from the change inenvironmental conditions when bringing them to a laboratory When using populations of...
... Subsequently, material inventory is analyzed taking into consideration the effects of integration in levels and Any possible improvement using the remaining CDOFs are considered in level 12 Chapter ... simplifications and approximations are often required, and so inaccuracy is an inherited disadvantage Chapter Introduction To tackle the complex problem of combined design and control, and avoid ... recycle and energy integration, to satisfy environmentaland safety regulations, and to have a certain degree of flexibility to handle fluctuations such as production rate changes (in response to...