intra cortical inhibition in the regulation of receptive field properties and neural plasticity in the primary visual cortex
Neuronal correlates of perceptual salience in local field potentials in the primary visual cortex
... add to the evidence supporting binding-by-synchrony hypothesis as the mechanism underlying visual grouping in the primary visual cortex Also, these findings indicate that primary visual cortex ... segmentation and visual binding in the next section 2.2 Visual binding and binding-by-synchrony Although the binding-by-synchrony hypothesis was proposed initially as the mechanism underlying visual ... performed In the next section, we discuss why the primary visual cortex could be a good candidate 2.3 Role of the primary visual cortex In addition to the question of how neurons bind together, the other...
- 138
- 398
- 0
Neuronal correlates of perceptual salience in spike trains from the primary visual cortex
... Summary In this thesis, we examined the representation of visual saliency in the responses of neurons in the primary visual cortex We investigated this by recording from the primary visual cortex of ... spike train during trial T xviii Chapter Introduction The primary visual cortex (V1) is the best studied visual area in the brain However, our understanding of how cortical neurons encode and process ... non-overlapping receptive fields As the distance between the two cells increased, the overlap of the receptive fields of the cells participating in the interactions gradually diminished Several groups in...
- 143
- 233
- 0
Population coding in the primary visual cortex
... to integrate the activity of on the order of 100 inputs In another study examining the activity of cortical neurons of behaving monkeys, McAdams and Maunsell (1999) explicitly tested the hypothesis ... reliability of neurons in the primary visual cortex of cats, presented with both natural scenes and drifting sine gratings We examined the variability of both spike counts and spike times in windows ... identify the direction of a subset of coherently moving dots embedded in a field of randomly moving dot kinematograms while maintaining fixation on a small spot on the stimulus screen Comparing the...
- 0
- 140
- 0
Báo cáo y học: "Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts" docx
... transcription of the MMP-1 gene depends on enhanced binding of c-Jun to the most proximal AP-1 binding site of the MMP-1 promoter On the other hand, we have shown that inhibition of SP1 binding to the ... results in a specific increase in binding of cJun to the most proximal AP-1 site of the MMP-1 promoter We next investigated whether binding of c-Jun to the MMP-1 promoter in the presence of bortezomib ... (ORFs) of the MMP-1 or COL1A2 genes (Figure 6a, b) In conclusion, the effect of PI dominates the influence of TGF-β in controlling the binding of both SP1 to COL1A2 and c-Jun to MMP-1 Discussion The...
- 14
- 286
- 0
The role of TRIP br proteins in the regulation of mammalian gene transcription and cell cycle progression
... Features PHD zinc finger protein PHD zinc finger protein Composite PHD zinc fingerbromodomain proteins PHD zinc finger protein Bromodomain protein PHD zinc finger proteins PHD zinc finger protein Composite ... Prominent examples of PHD zinc finger and/ or bromodomaincontaining proteins The (*) label designates disease-associated PHD zinc finger and/ or bromodomain-containing proteins Conservation of the ... growth (in the cases of Rsc1 and Rsc2) 15 (1.2.2) The role of PHD zinc fingers and bromodomains in the regulation of eukaryotic gene transcription To date, the molecular function(s) of the PHD zinc...
- 170
- 222
- 0
Báo cáo Y học: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells pdf
... accordance with the postulated obligatory role of the protein in steroidogenesis, we detected the protein and its mRNA in all steroidogenic tissues including placenta and brain [32] Inhibition of ACTH ... Expectedly, incubation of [1-14C]AA-CoA in the presence of the purified enzyme resulted in the release of AA Km and Vmax values obtained for the reactions were 4.1 and lM and 948 and 193 nmolÆmin)1Æmg)1 ... Fig Combined effect of triacsin C and NDGA on steroid hormone synthesis Y1 cells were preincubated in the presence or the absence of increasing concentrations of triacsin C (4 h, 37 °C) and of NDGA...
- 9
- 470
- 0
Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx
... determinations of the sum of the kinetic elasticity coef®cients (i.e 5.6 and 5.5) are in good agreement with each other Thus, 72% (5.6 of 7.8) of the homeostasis of DNA supercoiling in the wild-type ... Extrapolation of our ®ts in Fig to an aLk of (corresponding to coumermycin inhibition) indicates a 2.8-fold induction Fusion of the topA promoters to the galactokinase gene showed a twofold to fourfold inhibition ... Supercoiling assay DNA supercoiling was assessed in terms of the linking number of intracellular plasmid pBR322 [18] DNA supercoiling was expressed as the active linking number, aLk, which is the...
- 8
- 476
- 0
báo cáo khoa học: "Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by lipoic acid: role in cancer prevention and therapy" ppt
... cell killing and eradication The mechanism by which LA acts in dual cell cycle checkpoint control may be complex and appears to involve at least the down regulation of cyclin E/cdk2 and cyclin B1/cdk1 ... permeability and contributing to its relocalization to the nucleus, and thereby promoting the induction of caspase-independent apoptosis A companion and equally important change in this regard may be the ... caspase-dependent apoptosis [34] Indeed, there is increasing awareness and acceptance regarding the coexistence of caspase-dependent and caspase-independent apoptotic and other modes of cell death for a given...
- 8
- 525
- 0
Guide to U.S. Regulation of Genetically Modified Food and Agricultural Biotechnology Products
... produced and used in a living plant, or in the produce thereof, and the genetic material necessary for the production of such a pesticidal substance It also contains any inert ingredient contained in ... on the environment” U.S.C 136a(c)(5) FIFRA defines the environment as “water, air, land, and all plants and man and other animals living therein, and the interrelationships which exist among these.” ... in a fast moving field We believe this interagency coordinating committee should monitor the changing scene of biotechnology and serve as a means of identifying potential gaps in regulation in...
- 36
- 591
- 0
SEC Finalizes Rules to Implement Dodd-Frank Act Regulation of Private Investment Funds and Their Managers ppt
... by fund investors, (xi) whether clients of the adviser are solicited to invest in the fund and what percentage of the other clients has invested in the fund, and (xii) information concerning five ... (iv) information about the organization of the fund, including whether it is a master or a feeder fund, and information about the regulatory status of the fund and its adviser, including the exclusion ... (viii) the type of investment strategy employed by the adviser8 within seven broad categories, (ix) the number and the types of investors in the fund, (x) the minimum amounts required to be invested...
- 15
- 367
- 0
Báo cáo khoa học: Regulation of maize lysine metabolism and endosperm protein synthesis by opaque and floury mutations potx
... with the wild-type maize [9,30,31] Estimating the percentage of lysine in true proteins by assuming the lysine content of nonzeins is independent of genotype and equal to g per 100 g of proteins, ... particularly in fl1 and fl2 The presence of AK activity more insensitive to lysine and threonine inhibition was confirmed when both amino acids were tested together, resulting in less than 50% inhibition of ... to 55.6% in the Oh43o1 mutant The inhibitory effect of threonine on AK activity was much lower when compared with the effect of lysine, resulting in 11.1% inhibition of AK activity in the wild...
- 11
- 354
- 0
the chemistry of nanomaterials. synthesis, properties and applications, 2004, p.761
... designing the synthesis of such materials, and it seems colloid chemistry is gaining a new lease of life from a better understanding of the assembly of nanoparticulates Much of the understanding of ... ratio The distribution of particle sizes The nature of the core The nature of the shell The nature of the final coat The above describe the physical composition of the particle; other properties ... using a molecule, ligand, which binds to the surface of the nanoparticle, the growth of particles is further inhibited by e.g limiting the supply of the constituents forming the material, either...
- 761
- 541
- 0
báo cáo hóa học:" Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a" pot
... V617F and the development of MPD [1,9] Further characterization of the molecular changes in MPD neutrophils could lead to a better understanding of the development of these diseases and their clinical ... is indicated by the bar and is expressed as -1 times the log of the p value The line represents the ratio of the number of genes in a given pathway that meet the cutoff criteria divided by the ... sights into the molecular changes in ET and PV PV and ET neutrophils were characterized by the down -regulation of miR-1 and miR-133a and changes in the expression of many genes involved in inflammation...
- 17
- 524
- 0
Báo cáo hóa học: " Research Article Sparse Approximation of Images Inspired from the Functional Architecture of the Primary Visual Areas" doc
... orientations and scales (a) Schematic contours of the filters in the Fourier domain The Fourier domain origin (DC component) is located at the center of the inset and the highest frequencies lie on the ... ∈ RM , W ∈ RM ×N , and W T ∈ RN ×M , N being the number of pixels in the image and M the size of the dictionary (with M > N) The previous steps of thresholding, inhibition, and facilitation allowed ... The second objective of this study is to approach visual cortex understanding and image processing From the image processing point of view, one important novelty consists in achieving denoising...
- 16
- 262
- 0
Báo cáo hóa học: " Use of Time-Frequency Analysis and Neural Networks for Mode Identification in a Wireless Software-Defined Radio Approach" pptx
... at the Department of Biophysical and Electronic Engineering (DIBE) of the University of Genoa He obtained the Laurea degree and the Ph.D in telecommunications and signal processing in 1987 and ... from the sampled version of a signal By this procedure, the device classifies the standards available in the environment before decoding and extracting the modulated information contained in the ... 3a) According to the distribution profile for any signal of fixed length and moving on the time axis, the WV transform of a signal s(t) increases up to the middle of the time window, then it decreases...
- 13
- 455
- 0
Báo cáo y học: "Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation" potx
... promoting MSC adipogenesis while repressing osteogenesis [52] The binding of PPARγ to various ligands, including longchain fatty acids and thiazolidinedione compounds, induces the transactivation and ... between extracellular and intracellular signaling networks Finally, alterations in the MSC niche will help to determine the intrinsic and extrinsic specificity of MSC regulators In an elegant model ... harnessing the healing powers of adult stem cells in the future Competing interests The authors declare that they have no competing interests Acknowledgment This work was supported by the Intramural...
- 10
- 526
- 0
Redox regulation of estrogen receptor alpha and sodium hydrogen exchanger 1 gene expression by hydrogen peroxide
... ligand-binding pocket The AF-2 in the LBD of ER is composed of amino acids in helix 3, 4, and 12 The position of helix 12 changes when ER binds to ligands and therefore is the key in discriminating ... cysteine residues at their DNA binding domains (Haddad, 2002) The oxidation of these critical cysteine residues often leads to the inactivation of their DNA binding activity, thereby inhibiting ... exclusively in the brain NHE6 to NHE9 are found in the membrane of intracellular organelles where they are involved in the maintenance pH in these compartments NHE6 is expressed in the early recycling...
- 253
- 317
- 0
Regulation of global banking principles and policies taylor
... blank Introduction: The Global Financial System and the Problems of Regulation This book examines the principles, policy, and law relating to the regulation of international banking Other regulation ... States, the cost of resolving the savings and loan crisis of the late 1980s was roughly 5.1% of GDP According to the IMF, the costs of restructuring banking systems as the result of banking crises ... losses of funds and subsequent insolvency We will come across examples of these problems in future chapters: they include Continental Illinois in the U.S and Northern Rock in the U.K The Changing...
- 353
- 631
- 0
Báo cáo khoa học: Purification and characterization of NTPDase1 (ecto-apyrase) and NTPDase2 (ecto-ATPase) from porcine brain cortex synaptosomes doc
... NTPDase2 in the synapse has not been explained Homogeneity of the obtained preparations allowed a precise analysis and comparison of the kinetic properties of both enzymes The results of these experiments ... Cu2+ and Ba2+ were strong inhibitors of the analysed enzymes, whereas the presence of monovalent ions in the incubation mixture did not affect the rate of ATP and ADP hydrolysis (Table 4) ATP and ... presence of these ions increased only 0.5 Fig PAGE of NTPDase1 and NTPDase2 during different steps of purification The proteins were separated on a 5% acrylamide gel containing 0.4% Triton X-100 and then...
- 8
- 321
- 0
Concise Dictionary of Pharmacological Agents Properties and Synonyms pdf
... ^ interferon y Actinac™ ^ chloramphenicol Actinex™ ^ masoprocol actinomycin AIV •» dactinomycin actinomycin B1 ^ dactinomycin actinomycin BIV •» dactinomycin actinomycin C [BAN] (cactinomycin ... BLOCKER aminacrine hydrochloride •» aminacrine aminoacetic acid ^glycine aminoacridine •» aminacrine 9-aminoacridine * aminacrine L-N G -aminoarginine ~ L-NNA aminobenzoate •*• lisadimate aminobenzoic ... from the guanidino group of aginine; a number of NITRIC OXIDE SYNTHASE INHIBITORS are derivatives of L-arginine 8-arginineoxytocin ~ argiprestocin arginine vasopressin * argipressin; vasopressin...
- 359
- 502
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy