... Shanahan F. Insulin-dependent diabetes melli-tus and coeliac disease. Lancet 1997; 349: 1096-7.19. Pocecco M, Ventura A. Coeliac diseaseand insulin-depen-dent diabetes mellitus: a causal association? ... ofceliac disease in a sample of Turkish children and adoles-cents with type 1 diabetes mellitus. J Clin Gastroenterol2006; 40: 655-7.4. Tanure MG, Silva IN, Bahia M, et al. Prevalence of celiac disease ... coeliac disease and risk of autoimmune disorders in subjects withType I diabetes mellitus. Diabetologia 2001; 44: 151-5.9. Saukkonen T, Ilonen J, Akerblom HK, et al. Prevalence ofcoeliac disease...
... emergence and transmission of infectious disease agents.Simple logic suggests that climate can affect infectious disease patterns be-cause disease agents (viruses, bacteria, and other parasites) and ... of data to understand geographic patterns of disease (Jordanova, 1979; Riley, 1987).THE EARLY MERGER OF METEOROLOGY AND MEDICINEThe quests to understand weather, climate, anddisease all posed ... meteo-122Climate and Infectious Diseases:The Past as PrologueThe following review addresses the origins of environmental medicine and its legacy for our current understanding of climate and infectious disease...
... physical and mental well-being and general quality of life. It promotes healthy growth and development, prevents diseaseand unhealthy weight gain, and also improves social connectedness and societal ... and type 2 diabetes in Mexico [Villalpando, et al., 2010].4.4.3 Mexico City and non-heart-healthy behaviours4.4.3.1 Diet, nutrition and physical activityWithin Mexico City both under- and ... Paulo andcardiovascular disease Over time, Brazil has witnessed a decline in the mortality rate from both heart disease and stroke; from 68.2 to 40.9 per 100,000 habitants for stroke, and...
... and it has been named as metabolic syndrome [4]. There are mainly three types of diabetes which include Type 1 diabetes, Type 2 diabetes including a related condition called pre -diabetes and ... filtered by the glomerulus. Pathophysiology and Complications of DiabetesMellitus 36 7. Diagnosis of diabetes, its complications and management Diabetes screening is recommended for: Overweight ... mainly long standing. These include: Chronic complicationsBlindness(Mainly cataract and retinopathy) Renal Disease Hypertension Cardiac Diseaseand Stroke Amputations Nervous System Disease...
... 30Introduction Diabetes mellitusandcardiovascular diseases are challenging medical and social problems. Patients with diabetesmellitus are at a higher risk of devel-oping vascular dysfunction and ... metabolic abnormalities and diseases such as type 2 diabetes mellitus, obesity and the metabolic syndrome (30). In these conditions there is an elevation of both glucose and free fatty acid ... oxygen and nitrogen species, lowered antioxidant defense and alterations of enzymatic pathways in humans with poorly con-trolled diabetesmellitus can contribute to endothelial, vascular and...
... health and disease. Through careful synthesis of disease conditions revealed inthousands of piecemeal studies and data systems, it construct-ed a comprehensive portrait of diseases, injuries, and ... accounts mapping health expenditures byage, sex, anddiseaseand injury causes (1998) and carried outan influential national burden of diseaseand risk factors study(1999). At the World Health ... Methods and Data 51Global and Regional Mortality in 2001 68Estimating Incidence, Prevalence, and YLD: Methods and Data 73Burden of Disability and Poor Health in 2001 85Global Burden of Disease...
... Gaucher disease. BloodCells, Molecules and Diseases, 24, 296–302.Cox, T.M. (2001) Gaucher disease: Understanding the molecularpathogenesis of sphingolipidoses. Journal of Inherited Metabolic Disease, ... feeling in the medical and research community thatthere is little need to understand the basic mechanisms of disease development and progression. However, a renewedinterest in GD, and in the biology ... IL-6 and Il-10may contribute to osteopenia, IL-1b, TNFa and IL-6 maycontribute to activation of coagulation and hypermetabolism,IL-6 and IL-10 to gammopathies (Brautbar et al, 2004) and MM...
... based on recommendationsfrom German and international expert societies (e1, 8, e4, e5, 13) and on longstandingexperience in the treatment, sports advice, and care provided in sports activities ... of perception and movement determine not only its physical and motor development but also crucially influenceits emotional, psychosocial, and cognitive development (16, e7). Heart disease often ... peers means improved quality of life and has a strong social and socializing aspect for children and adolescents. Being forbidden to participate in sports and/ or limitations to the extent to which...
... and S b0thalassaemia were consis-tently smaller and less sexually mature thanthose with SC diseaseand S bzthalassae-mia. Sexual maturation followed the patternof height and weight, and ... are linked toincreased risk of cardiovasculardisease and stroke.114Plasma homocysteine is reportedto be elevated in adults115 and chil-dren116,117with SCD and significantly sowhen complicated ... mortality in all children, and contributes to poor clinical outcome and severity of disease in children with SCD.Despite major advances in understandingthe molecular and genetic basis for SCD,there...
... levels.TEC kinases anddisease A. Hussain et al.2002 FEBS Journal 278 (2011) 2001–2010 ª 2011 The Authors Journal compilation ª 2011 FEBSMINIREVIEWTEC family kinases in health anddisease – loss-of-functionof ... loss-of-functionof BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYKAlamdar Hussain1,2,*, Liang Yu1,3,*, Rani Faryal1,2, Dara K. Mohammad1, Abdalla J. Mohamed1,4 and C. I. Edvard ... ITK–SYK fusion oncogene inducesa T-cell lymphoproliferative disease in mice mimickinghuman disease. Cancer Res 70, 6193–6204.TEC kinases anddisease A. Hussain et al.2010 FEBS Journal 278 (2011)...
... mammalian lens and guard against ischemic and reper-fusion injury due to heart attack and stroke. On the other hand, mutatedsHSPs are implicated in diseases such as desmin-related myopathy and theyhave ... antiapoptotic potential and decrease cell protection by Hsp25. In another example,Hsp27 and aB-crystallin appear in Parkinson’s disease Y. Sun and T. H. MacRae Small heat shock proteins and disease FEBS ... aB-crystallin and HspB2, develop as expectedunder nonstress conditions and show normal contrac-tility [85]. However, when exposed to ischemia and Small heat shock proteins anddisease Y. Sun and T....