... Molecular modelingofthe dimeric structureof LPL Two dimeric model structures of LPL were constructed using INSIGHT II version 2000 on a Silicon Graphics workstation The model structureofthe closed ... established Of two possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies ofthe chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL ... structureof monomeric LPL was duplicated and superimposed on the crystal structureofthe horse PL dimer After the energy minimization by setting at iteration of 300 cycles or energy level of...
... presented structure and showed, in particular, the configuration of ManNAc to be D From the combined the data on the structures ofthe isolated oligosaccharides, the overall structureofthe P frisingensis ... positions of all the other monosaccharides were confirmed by GC-MS data ofthe methylated products to be as presented in Scheme Deamination ofthe products of complete deacylation ofthe LPS led to the ... H3 of Kdo C and H6 of Kdo D is possible only in the case of an a-configuration of residue D, linked to O4 of Kdo C, as follows from molecular modelingThe unusual position ofthe H3 signals of...
... 5255 of internal cavities capable of containing water molecules in the homologous Rossman fold ofthe soluble members ofthe HAD superfamily (Fig 5) We used the high-resolution structures ofthe ... rather on the regions initiating or impairing insertion of a segment in the membrane Therefore, in the case of M8 where the length ofthe M8 recombinant peptide is probably shorter than that of ... group, located in the membrane domain, almost connects the region homologous to the ion-binding site to the extracytoplasmic moiety ofthe molecule The positions ofthe internal polar cavities...
... in their homing position Each process blocked in the course of task execution relies on the other processes for removal ofthe barrier Essentially, the proof in question is a demonstration ofthe ... they are called the P-operation and the V-operation A process, "Q" say, that performs the operation " P (sem)" decreases the value ofthe semaphore called "sem" by If the resulting value ofthe ... the value ofthe semaphore called "sem" by If the resulting value ofthe semaphore concerned is positive, the V-operation in question has no further effect; if, however, the resulting value of...
... the deciduous effect ofthe respective parts of Z japonica The δ13C in the roots and rhizomes seems to be larger than the δ13C in the leaves and stems For the same species of seagrass, when the ... we think that the characteristics ofthe fatty acid structure in the leaves and stems differ from those ofthe roots and rhizomes because the content ofthe fatty acid 18:3n3 in the leaves and ... designates the sum of all the fatty acids with < 5% content The three fatty acids 16:0, 18:2n6c, 18:3n3 were found > 15% in the leaves and stems of all the samples of Z - 104 - Journal of Water...
... 1.6 Design ofthe Study The paper is designed in four chapters Chapter one: The introduction presents the rationale ofthe study, the aims ofthe study, scope ofthe study, methods ofthe study, ... most ofthe themes in the text belong to topical theme Of 33 clauses and clause complexes 27 have unmarked theme and have marked theme Using a proper noun at the beginning ofthe text, then the ... called Theme and Rheme The Theme served as the point of departure ofthe message (Halliday 1994:37), which in English coincides with the initial element(s) ofthe clause; and the Rheme is the remainder...
... n The n-period interest rate equals the average ofthe one-period interest rates expected to occur over the n-period life ofthe bond Expectations Theory • Explains why the term structureof ... over the life ofthe long-term bond • Buyers of bonds not prefer bonds of one maturity over another; they will not hold any quantity of a bond if its expected return is less than that of another ... Structureof Interest Rates • The risk structureof interest rates looks at bonds with the same term to maturity and different interest rates • The term structureof interest rates looks at the...
... regulatory oversight ofthe national payments system, operated by the CPA • acts as the holder of deposit accounts ofthe federal government, the directly clearing members ofthe CPA, international organizations ... for the operation ofthe Bank rests with a Board of Directors, which consists of fifteen members: • the governor (currently Mark Carney, who is the chief executive officer and chairman ofthe ... the Board of Directors) • the senior deputy governor, • the deputy minister of finance, and • twelve outside directors Copyright 2011 15 - Formal Structureofthe Bank of Canada II • The Board...
... system the precession ofthe orbit of Mercury and the bending of light by the Sun Over the ensuing decades theoretical analyses deepened the understanding ofthe theory and exhibited the richness ... as the circular structure in the lower half ofthe dewar The rest ofthe internal components are structures for cooling the bar to 4.2 K, for bringing out the signal from the transducer on the ... radiation they emit in the last stages of their formation • The use of gravitational waves to probe the universe of complex astronomical phenomena by the decoding ofthe details ofthe gravitational...
... describing the state of being ofthe things under the observation ofthe astronauts in the new planet Most ofthe processes are in the simple past tense (25/36) They are used in the narrative portion The ... Subject The spaceship The planet They There The spaceship The two astronauts The woman It She We It Both of them They All plants and Animals They They Everything The man Nothing Something He I The ... ability/neg complexes analysed for theme, 17 have Our analysis shows that most ofthe unmarked theme and have marked themes in the text belong to the plane of theme At the beginning ofthe text,...
... (Leu104–Pro111) Indicative ofthe tightness ofthe fit, there are a large number (30) of atom-to-atom van der Waals’ contacts between the Tyr205 side chain and importin-a (Table 2) The numbers of contacts are ... aliphatic portion ofthe side chain fits into the hydrophobic alcove and allows the charged head group access to the solvent on the other side The extended side chain of Arg206 allows for the same favourable ... supporting the assignment of o o CLIC4 NLS residues in these binding positions This analysis is therefore a recommended method of structural examination in other importin-a:NLS complexes to ensure the...
... because the tertiary structureof ApeSOD has not been elucidated In the present study, for the first time, we describe the crystal structureof ApeSOD In particular, we focus on the coordination ofthe ... NE2 of His31, bound to the metal, in the company of a water oxygen, from the apical positions The manga˚ nese was only 0.06 A out ofthe equatorial plane (Table 3) The angles around the metal cofactor ... [26] These findings lead to the hypothesis that Fe-bound ApeSOD mimics the product-inhibited form and the shift of Tyr39 suppresses the release ofthe peroxide product This may be one ofthe reasons...
... take the use ofthe special structureofthe Einstein equations one step further by deriving unexpected regularity properties of optical functions which are essential in the proof ofthe Main Theorem ... properties ofthe components ofthe Riemann curvature tensor Rαβγδ The remaining sections are occupied with the proof ofthe Asymptotics Theorem We give a detailed description of their content and the ... derivatives ofthe traceless part of χ A similar observation holds for another null component ofthe Hessian ofthe optical function, η The role ofthe Raychaudhuri equation is taken by the transport...
... and mutant structure are in the same range as the differences between the two molecules ofthe asymmetric unit ofthe wild-type structure Neither the mutation nor the different crystallization ... out ofthe catalytic pocket upon phytate binding Here, PhyK mimics the phytate-bound structureof AppA, even in the absence of sulfate ions The side chain ofthe corresponding Glu212 bends out of ... is the only direct contact between the protein backbone and the substrate The side chain of Thr292 is found to recognize the 2-phosphate in both the binding model of PhyK and the crystal structure...
... be important to limit the extent of exposure ofthe deposit bank to the trading entities within the same banking group Strengthening the governance and control of banks Governance and control is ... serving the needs of citizens, the EU economy and the single market During the course of its work, the Group has organised hearings with a large number of stakeholders, be they providers of banking ... to the intensification ofthe sovereign debt crisis in the euro area The pricing of risk in the repo market has become more dependent on the geographic origin of both the counterparty and the...
... as the amino acid numbers The alternative conformations ofthe Trp–Met couple can be observed; the arrows indicate the unidirectional movement ofthe two protein residues upon ligand binding The ... metalbound hydroxyl group onto the substrate, as observed in other members ofthe amidohydrolase superfamily [24,25] However, as no structureofcomplexes with either the substrate, product or inhibitors ... in the crystal, and a mixture of monomeric and dimeric forms in solution [18] Therefore, the available structural data suggest Fig Ribbon representation ofthe overall structureof hACMSD The...
... with the other charged groups In the NMR structures, this side ˚ chain of D40 is a short distance (£ A) from the side chains of H42 and R95 Finally, the aromatic ring of F126, placed close to the ... Fig 3B It is known that other side chains in the vicinity of these amino acids are also important for the activity Given the 3D structureofthe HtA active site, and the interactions between ... part of it As in other ribotoxins, the active site of HtA is buried, with the accessible surface area ofthe corresponding side chains very low Desolvation ofthe charged groups should affect their...
... ofthe NMR structures for the N-terminal domain (D) Aromatic side chains and one backbone trace ofthe NMR structureofthe C-terminal domain 1JOT), a plant lectin, as the closest structureThe ... constraints Solution structureof SAIL At3g16450.1 Assignment ofthe NOE peaks of At3g16450.1 and thestructure determination were accomplished by use ofthe cyana program [17,18] The structural statistics ... study demonstrates the power ofthe SAIL approach in determining thestructureof a larger protein by semi-automated means and with a minimal amount of material It also shows how a structure determined...